Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012113403> ?p ?o ?g. }
- W2012113403 endingPage "231" @default.
- W2012113403 startingPage "225" @default.
- W2012113403 abstract "NAD(H)-glutamate dehydrogenase (GDH; EC 1.4.1.2) is an abundant and ubiquitous enzyme that may exist in different isoenzymic forms. Variation in the composition of the GDH isoenzyme pattern is observed during plant development and specific cell, tissue and organ localization of the different isoforms have been reported. However, the mechanisms involved in the regulation of the isoenzymatic pattern are still obscure. Regulation may be exerted at several levels, i.e. at the level of transcription and translation of the relevant genes, but also when the enzyme is assembled to originate the catalytically active form of the protein. In Arabidopsis thaliana, three genes (GDH1, GDH2 and GDH3) encode three different GDH subunits (β, α and γ) that randomly associate to form a complex array of homo- and hetero-hexamers. In order to asses if the different Arabidopsis GDH isoforms may display different structural properties we have investigated their thermal stability. In particular the stability of GDH1 and GDH3 isoenzymes was studied using site-directed mutagenesis in a heterologous yeast expression system. It was established that the carboxyl terminus of the GDH subunit is involved in the stabilization of the oligomeric structure of the enzyme." @default.
- W2012113403 created "2016-06-24" @default.
- W2012113403 creator A5003751387 @default.
- W2012113403 creator A5043133758 @default.
- W2012113403 creator A5057459234 @default.
- W2012113403 creator A5070678967 @default.
- W2012113403 creator A5074725036 @default.
- W2012113403 date "2014-10-01" @default.
- W2012113403 modified "2023-09-24" @default.
- W2012113403 title "Glutamate dehydrogenase isoenzyme 3 (GDH3) of Arabidopsis thaliana is less thermostable than GDH1 and GDH2 isoenzymes" @default.
- W2012113403 cites W1488582389 @default.
- W2012113403 cites W1530697014 @default.
- W2012113403 cites W1970093114 @default.
- W2012113403 cites W1970738935 @default.
- W2012113403 cites W1971448760 @default.
- W2012113403 cites W1973987357 @default.
- W2012113403 cites W1977935162 @default.
- W2012113403 cites W1991836622 @default.
- W2012113403 cites W1992215991 @default.
- W2012113403 cites W1995254416 @default.
- W2012113403 cites W1995625308 @default.
- W2012113403 cites W2005314784 @default.
- W2012113403 cites W2015642465 @default.
- W2012113403 cites W2025513354 @default.
- W2012113403 cites W2025802688 @default.
- W2012113403 cites W2029667189 @default.
- W2012113403 cites W2039653715 @default.
- W2012113403 cites W2040802440 @default.
- W2012113403 cites W2055043387 @default.
- W2012113403 cites W2055318188 @default.
- W2012113403 cites W2060981239 @default.
- W2012113403 cites W2066477875 @default.
- W2012113403 cites W2071160125 @default.
- W2012113403 cites W2073347469 @default.
- W2012113403 cites W2079989472 @default.
- W2012113403 cites W2083553804 @default.
- W2012113403 cites W2101243221 @default.
- W2012113403 cites W2107797630 @default.
- W2012113403 cites W2107812243 @default.
- W2012113403 cites W2121712275 @default.
- W2012113403 cites W2137015675 @default.
- W2012113403 cites W2142553120 @default.
- W2012113403 cites W2142630217 @default.
- W2012113403 cites W2147170044 @default.
- W2012113403 cites W2152622208 @default.
- W2012113403 cites W2171268876 @default.
- W2012113403 doi "https://doi.org/10.1016/j.plaphy.2014.08.003" @default.
- W2012113403 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25180813" @default.
- W2012113403 hasPublicationYear "2014" @default.
- W2012113403 type Work @default.
- W2012113403 sameAs 2012113403 @default.
- W2012113403 citedByCount "11" @default.
- W2012113403 countsByYear W20121134032015 @default.
- W2012113403 countsByYear W20121134032018 @default.
- W2012113403 countsByYear W20121134032020 @default.
- W2012113403 countsByYear W20121134032021 @default.
- W2012113403 countsByYear W20121134032022 @default.
- W2012113403 countsByYear W20121134032023 @default.
- W2012113403 crossrefType "journal-article" @default.
- W2012113403 hasAuthorship W2012113403A5003751387 @default.
- W2012113403 hasAuthorship W2012113403A5043133758 @default.
- W2012113403 hasAuthorship W2012113403A5057459234 @default.
- W2012113403 hasAuthorship W2012113403A5070678967 @default.
- W2012113403 hasAuthorship W2012113403A5074725036 @default.
- W2012113403 hasConcept C104292427 @default.
- W2012113403 hasConcept C104317684 @default.
- W2012113403 hasConcept C108305142 @default.
- W2012113403 hasConcept C119795356 @default.
- W2012113403 hasConcept C143065580 @default.
- W2012113403 hasConcept C170493617 @default.
- W2012113403 hasConcept C181199279 @default.
- W2012113403 hasConcept C2775988993 @default.
- W2012113403 hasConcept C2777202666 @default.
- W2012113403 hasConcept C2779222958 @default.
- W2012113403 hasConcept C2779491563 @default.
- W2012113403 hasConcept C40767141 @default.
- W2012113403 hasConcept C53345823 @default.
- W2012113403 hasConcept C5527404 @default.
- W2012113403 hasConcept C55493867 @default.
- W2012113403 hasConcept C61174792 @default.
- W2012113403 hasConcept C86803240 @default.
- W2012113403 hasConceptScore W2012113403C104292427 @default.
- W2012113403 hasConceptScore W2012113403C104317684 @default.
- W2012113403 hasConceptScore W2012113403C108305142 @default.
- W2012113403 hasConceptScore W2012113403C119795356 @default.
- W2012113403 hasConceptScore W2012113403C143065580 @default.
- W2012113403 hasConceptScore W2012113403C170493617 @default.
- W2012113403 hasConceptScore W2012113403C181199279 @default.
- W2012113403 hasConceptScore W2012113403C2775988993 @default.
- W2012113403 hasConceptScore W2012113403C2777202666 @default.
- W2012113403 hasConceptScore W2012113403C2779222958 @default.
- W2012113403 hasConceptScore W2012113403C2779491563 @default.
- W2012113403 hasConceptScore W2012113403C40767141 @default.
- W2012113403 hasConceptScore W2012113403C53345823 @default.
- W2012113403 hasConceptScore W2012113403C5527404 @default.
- W2012113403 hasConceptScore W2012113403C55493867 @default.
- W2012113403 hasConceptScore W2012113403C61174792 @default.
- W2012113403 hasConceptScore W2012113403C86803240 @default.