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• W2012120903 abstract "The neurotoxin 5,7-dihydroxytryptamine (5,7-DHT) is often used in neonatal rats to induce specific, rapid, and permanent depletion of brain serotonin (5-HT). One assumed benefit of using this drug in neonates is that it is well-tolerated, with pups exhibiting few side effects normally attributed to 5-HT depletion. Here, we present evidence that 5,7-DHT administered neonatally induces seizure-like behavior, decreases weight gain, and increases plasma corticosterone without depletion of brain 5-HT." @default.
• W2012120903 created "2016-06-24" @default.
• W2012120903 creator A5028239411 @default.
• W2012120903 creator A5035809946 @default.
• W2012120903 date "2004-07-01" @default.
• W2012120903 modified "2023-09-25" @default.
• W2012120903 title "Neural and hormonal consequences of neonatal 5,7-dihydroxytryptamine may not be associated with serotonin depletion" @default.
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• W2012120903 doi "https://doi.org/10.1016/j.devbrainres.2004.05.001" @default.
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