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• W2012124471 startingPage "529" @default.
• W2012124471 abstract "In patients with acute myocardial infarction, intravenous streptokinase therapy recanalizes 40% to 45% of occluded coronary arteries and reduces mortality by 25%. Recombinant tissue-type plasminogen activator (rt-PA) therapy is more potent for coronary arterial thrombolysis, producing both more rapid and more frequent (65% to 70%) reperfusion. Side effects (mainly reocclusion and bleeding) of streptokinase and rt-PA therapy are not markedly different. Whether the higher efficacy of rt-PA therapy will translate into a comparably larger reduction of morbidity and mortality remains to be determined in large comparative clinical trials. Both agents are available for clinical use. At present, the choice of agent for treating acute myocardial infarction must be based on consideration of the lower cost of streptokinase therapy compared with the established higher efficacy of rt-PA therapy for coronary recanalization." @default.
• W2012124471 created "2016-06-24" @default.
• W2012124471 creator A5023982501 @default.
• W2012124471 date "1990-04-01" @default.
• W2012124471 modified "2023-09-27" @default.
• W2012124471 title "Coronary Thrombolysis: Streptokinase or Recombinant Tissue-Type Plasminogen Activator?" @default.
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• W2012124471 doi "https://doi.org/10.7326/0003-4819-112-7-529" @default.
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