FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012124624> ?p ?o ?g. }

• W2012124624 endingPage "106" @default.
• W2012124624 startingPage "100" @default.
• W2012124624 abstract "The aim of this study was to determine the localization of the rate-limiting enzyme indoleamine 2, 3-dioxygenase (IDO) and its metabolite in mice kidneys after adriamycin (ADR)-induced renal failure. We also examined the effect of l-tryptophan (Trp) administration on this model. BALB/c mice were treated with 15 mg/kg ADR to induce renal failure. The change of IDO and l-kynurenine (Kyn) following ADR-induced renal failure was examined by immunostaining combined with hematoxylin and eosin (HE) and Periodic acid-Schiff (PAS) staining for morphological analysis, and the concentration of l-Kyn was measured by HPLC. The effect of l-Trp administration on ADR-induced renal failure was also investigated. Time-dependent increase of IDO immunostaining was observed in tubular cells from Day 4 after ADR injection. It was found that mice fed with l-Trp had less chance of renal failure at four days after ADR injection than mice untreated with l-Trp, but not at seven days. Further, l-Trp treatment significantly suppressed an increased level of TNF-alpha mRNA, but not of TGF-beta and IL1-beta after renal injury. Local IDO expression in tubules was induced markedly after ADR- induced renal failure. l-Trp administration can be effective in suppressing ADR-induced renal failure at an early stage." @default.
• W2012124624 created "2016-06-24" @default.
• W2012124624 creator A5009725511 @default.
• W2012124624 creator A5015424874 @default.
• W2012124624 creator A5015580452 @default.
• W2012124624 creator A5041000766 @default.
• W2012124624 creator A5047372955 @default.
• W2012124624 creator A5068174476 @default.
• W2012124624 creator A5082969604 @default.
• W2012124624 creator A5089423258 @default.
• W2012124624 date "2012-08-01" @default.
• W2012124624 modified "2023-10-16" @default.
• W2012124624 title "Pre-administration of L-tryptophan improved ADR-induced early renal failure in mice" @default.
• W2012124624 cites W132271162 @default.
• W2012124624 cites W1538908810 @default.
• W2012124624 cites W1549139000 @default.
• W2012124624 cites W1560572144 @default.
• W2012124624 cites W1648872901 @default.
• W2012124624 cites W1971420166 @default.
• W2012124624 cites W1971900958 @default.
• W2012124624 cites W1975929837 @default.
• W2012124624 cites W1977753547 @default.
• W2012124624 cites W1999755139 @default.
• W2012124624 cites W2034377200 @default.
• W2012124624 cites W2034698282 @default.
• W2012124624 cites W2038466233 @default.
• W2012124624 cites W2044115789 @default.
• W2012124624 cites W2046859937 @default.
• W2012124624 cites W2055126213 @default.
• W2012124624 cites W2066517663 @default.
• W2012124624 cites W2079399560 @default.
• W2012124624 cites W2087204421 @default.
• W2012124624 cites W2109207751 @default.
• W2012124624 cites W2120937496 @default.
• W2012124624 cites W2138302361 @default.
• W2012124624 cites W2158840819 @default.
• W2012124624 cites W2164155587 @default.
• W2012124624 cites W4247406457 @default.
• W2012124624 doi "https://doi.org/10.1016/j.lfs.2012.06.018" @default.
• W2012124624 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22749866" @default.
• W2012124624 hasPublicationYear "2012" @default.
• W2012124624 type Work @default.
• W2012124624 sameAs 2012124624 @default.
• W2012124624 citedByCount "6" @default.
• W2012124624 countsByYear W20121246242015 @default.
• W2012124624 countsByYear W20121246242017 @default.
• W2012124624 countsByYear W20121246242018 @default.
• W2012124624 countsByYear W20121246242019 @default.
• W2012124624 countsByYear W20121246242023 @default.
• W2012124624 crossrefType "journal-article" @default.
• W2012124624 hasAuthorship W2012124624A5009725511 @default.
• W2012124624 hasAuthorship W2012124624A5015424874 @default.
• W2012124624 hasAuthorship W2012124624A5015580452 @default.
• W2012124624 hasAuthorship W2012124624A5041000766 @default.
• W2012124624 hasAuthorship W2012124624A5047372955 @default.
• W2012124624 hasAuthorship W2012124624A5068174476 @default.
• W2012124624 hasAuthorship W2012124624A5082969604 @default.
• W2012124624 hasAuthorship W2012124624A5089423258 @default.
• W2012124624 hasConcept C126322002 @default.
• W2012124624 hasConcept C134018914 @default.
• W2012124624 hasConcept C185592680 @default.
• W2012124624 hasConcept C204232928 @default.
• W2012124624 hasConcept C2776706248 @default.
• W2012124624 hasConcept C2777477808 @default.
• W2012124624 hasConcept C2777503454 @default.
• W2012124624 hasConcept C2780091579 @default.
• W2012124624 hasConcept C4224716 @default.
• W2012124624 hasConcept C515207424 @default.
• W2012124624 hasConcept C55493867 @default.
• W2012124624 hasConcept C71924100 @default.
• W2012124624 hasConcept C98274493 @default.
• W2012124624 hasConceptScore W2012124624C126322002 @default.
• W2012124624 hasConceptScore W2012124624C134018914 @default.
• W2012124624 hasConceptScore W2012124624C185592680 @default.
• W2012124624 hasConceptScore W2012124624C204232928 @default.
• W2012124624 hasConceptScore W2012124624C2776706248 @default.
• W2012124624 hasConceptScore W2012124624C2777477808 @default.
• W2012124624 hasConceptScore W2012124624C2777503454 @default.
• W2012124624 hasConceptScore W2012124624C2780091579 @default.
• W2012124624 hasConceptScore W2012124624C4224716 @default.
• W2012124624 hasConceptScore W2012124624C515207424 @default.
• W2012124624 hasConceptScore W2012124624C55493867 @default.
• W2012124624 hasConceptScore W2012124624C71924100 @default.
• W2012124624 hasConceptScore W2012124624C98274493 @default.
• W2012124624 hasFunder F4320320912 @default.
• W2012124624 hasFunder F4320322555 @default.
• W2012124624 hasIssue "3-4" @default.
• W2012124624 hasLocation W20121246241 @default.
• W2012124624 hasLocation W20121246242 @default.
• W2012124624 hasOpenAccess W2012124624 @default.
• W2012124624 hasPrimaryLocation W20121246241 @default.
• W2012124624 hasRelatedWork W1979910707 @default.
• W2012124624 hasRelatedWork W2020959757 @default.
• W2012124624 hasRelatedWork W2042033030 @default.
• W2012124624 hasRelatedWork W2044943066 @default.
• W2012124624 hasRelatedWork W2056872482 @default.
• W2012124624 hasRelatedWork W2127085070 @default.
• W2012124624 hasRelatedWork W2128286595 @default.

• next