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- W2012127237 abstract "We report on the first case of use of fondaparinux in early pregnancy. Treatment of venous thromboembolism during pregnancy is performed with aPTT-adjusted subcutaneous unfractionated heparin UFH). During the second and third trimester of pregnancy, anticoagulation may be switched to vitamin K antagonists [ [1] Büller H.R. Agnelli G. Hull R.D. Hyers T.M. Prins M.H. Raskob G.E. Antithrombotic therapy for venous thromboembolic disease: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest. 2004; 126 ([Suppl]): 401-428 Crossref Scopus (1316) Google Scholar ]. The limitations of treatment with UFH and vitamin K antagonists have prompted the use of low-molecular-weight (LMWH) heparins, especially of dalteparin, throughout pregnancy [ [2] Sanson B.J. Lensing A.W. Prins M.H. Ginsberg J.S. Barkagan Z.S. Lavenne-Pardonge E. et al. Safety of low-molecular-weight heparin in pregnancy: a systemic review. Thromb Haemost. 1999; 81: 668-672 PubMed Google Scholar ]. Local intolerance to UFH, LMW-heparins and danaparoid has been reported and may complicate treatment during pregnancy [ 3 Warkentin T.E. Heparin-induced skin lesions. Br J Haematol. 1996; 92: 494-497 Crossref PubMed Scopus (166) Google Scholar , 4 Harenberg J. Huhle G. Wang L.C. Hoffmann U. Bayerl Ch. Kerowgan M. Association of heparin-induced skin lesions, intracutaneous tests, and heparin-induced IgG. Allergy. 1999; 54: 473-477 Crossref PubMed Scopus (50) Google Scholar ]." @default.
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- W2012127237 title "Treatment of a woman with lupus and thromboembolism and cutaneous intolerance to heparins using fondaparinux during pregnancy" @default.
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- W2012127237 doi "https://doi.org/10.1016/j.thromres.2006.03.008" @default.
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