FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012135931> ?p ?o ?g. }

• W2012135931 endingPage "214" @default.
• W2012135931 startingPage "199" @default.
• W2012135931 abstract "Antibody fragments, especially single-chain Fv fragments, have been established for the generation of immunoliposomes for targeted drug delivery in cancer therapy and other applications. Bispecific immunoliposomes should be useful for dual targeting addressing inter- and intratumoral heterogeneity of tumor antigen expression. Here, we established a protocol to generate dual-targeted immunoliposomes using genetically engineered scFv molecules recognizing two different tumor-associated antigens, EGFR and CEA (CEACAM5), applying a step-wise insertion of antibody-coupled micelles into preformed PEGylated liposomes. The dual-targeted immunoliposomes retained binding activity for both antigens and combined the selectivity of both antibodies within one liposome. Thus, these dual-targeted immunoliposomes should be suitable to deliver therapeutic payloads to tumor cells expressing EGFR or CEA, or both antigens." @default.
• W2012135931 created "2016-06-24" @default.
• W2012135931 creator A5003257191 @default.
• W2012135931 creator A5004042607 @default.
• W2012135931 creator A5004541488 @default.
• W2012135931 creator A5032676593 @default.
• W2012135931 creator A5082328991 @default.
• W2012135931 date "2012-07-25" @default.
• W2012135931 modified "2023-10-17" @default.
• W2012135931 title "Dual Targeting of Tumor Cells with Bispecific Single-Chain Fv-Immunoliposomes" @default.
• W2012135931 cites W177160242 @default.
• W2012135931 cites W1967637067 @default.
• W2012135931 cites W1968583232 @default.
• W2012135931 cites W1968592882 @default.
• W2012135931 cites W1974973904 @default.
• W2012135931 cites W1975167491 @default.
• W2012135931 cites W1982321597 @default.
• W2012135931 cites W1989353157 @default.
• W2012135931 cites W1990455420 @default.
• W2012135931 cites W1993562925 @default.
• W2012135931 cites W2003291344 @default.
• W2012135931 cites W2007073167 @default.
• W2012135931 cites W2009344870 @default.
• W2012135931 cites W2025523616 @default.
• W2012135931 cites W2031428283 @default.
• W2012135931 cites W2032760352 @default.
• W2012135931 cites W2033439473 @default.
• W2012135931 cites W2034187117 @default.
• W2012135931 cites W2038300196 @default.
• W2012135931 cites W2041976502 @default.
• W2012135931 cites W2042975268 @default.
• W2012135931 cites W2056025993 @default.
• W2012135931 cites W2057343423 @default.
• W2012135931 cites W2057794558 @default.
• W2012135931 cites W2061655961 @default.
• W2012135931 cites W2061672022 @default.
• W2012135931 cites W2068115196 @default.
• W2012135931 cites W2083982805 @default.
• W2012135931 cites W2085824066 @default.
• W2012135931 cites W2086062452 @default.
• W2012135931 cites W2095577208 @default.
• W2012135931 cites W2137347544 @default.
• W2012135931 cites W2152006092 @default.
• W2012135931 cites W2157953106 @default.
• W2012135931 cites W2167261913 @default.
• W2012135931 cites W2169623960 @default.
• W2012135931 cites W2171792381 @default.
• W2012135931 cites W4251414021 @default.
• W2012135931 doi "https://doi.org/10.3390/antib1020199" @default.
• W2012135931 hasPublicationYear "2012" @default.
• W2012135931 type Work @default.
• W2012135931 sameAs 2012135931 @default.
• W2012135931 citedByCount "26" @default.
• W2012135931 countsByYear W20121359312014 @default.
• W2012135931 countsByYear W20121359312015 @default.
• W2012135931 countsByYear W20121359312017 @default.
• W2012135931 countsByYear W20121359312018 @default.
• W2012135931 countsByYear W20121359312019 @default.
• W2012135931 countsByYear W20121359312020 @default.
• W2012135931 countsByYear W20121359312021 @default.
• W2012135931 countsByYear W20121359312022 @default.
• W2012135931 countsByYear W20121359312023 @default.
• W2012135931 crossrefType "journal-article" @default.
• W2012135931 hasAuthorship W2012135931A5003257191 @default.
• W2012135931 hasAuthorship W2012135931A5004042607 @default.
• W2012135931 hasAuthorship W2012135931A5004541488 @default.
• W2012135931 hasAuthorship W2012135931A5032676593 @default.
• W2012135931 hasAuthorship W2012135931A5082328991 @default.
• W2012135931 hasBestOaLocation W20121359311 @default.
• W2012135931 hasConcept C126511603 @default.
• W2012135931 hasConcept C147483822 @default.
• W2012135931 hasConcept C153911025 @default.
• W2012135931 hasConcept C159654299 @default.
• W2012135931 hasConcept C178790620 @default.
• W2012135931 hasConcept C185154212 @default.
• W2012135931 hasConcept C185592680 @default.
• W2012135931 hasConcept C203014093 @default.
• W2012135931 hasConcept C2779820397 @default.
• W2012135931 hasConcept C502942594 @default.
• W2012135931 hasConcept C55493867 @default.
• W2012135931 hasConcept C86803240 @default.
• W2012135931 hasConceptScore W2012135931C126511603 @default.
• W2012135931 hasConceptScore W2012135931C147483822 @default.
• W2012135931 hasConceptScore W2012135931C153911025 @default.
• W2012135931 hasConceptScore W2012135931C159654299 @default.
• W2012135931 hasConceptScore W2012135931C178790620 @default.
• W2012135931 hasConceptScore W2012135931C185154212 @default.
• W2012135931 hasConceptScore W2012135931C185592680 @default.
• W2012135931 hasConceptScore W2012135931C203014093 @default.
• W2012135931 hasConceptScore W2012135931C2779820397 @default.
• W2012135931 hasConceptScore W2012135931C502942594 @default.
• W2012135931 hasConceptScore W2012135931C55493867 @default.
• W2012135931 hasConceptScore W2012135931C86803240 @default.
• W2012135931 hasIssue "2" @default.
• W2012135931 hasLocation W20121359311 @default.
• W2012135931 hasLocation W20121359312 @default.
• W2012135931 hasOpenAccess W2012135931 @default.
• W2012135931 hasPrimaryLocation W20121359311 @default.

• next