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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012137725> ?p ?o ?g. }

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• W2012137725 abstract "“Cross-priming” describes the activation of naïve CD8 + T cells by professional antigen-presenting cells that have acquired viral or tumor antigens from “donor” cells. Antigen transfer is believed to be mediated by donor cell–derived molecular chaperones bearing short peptide ligands generated by proteasome degradation of protein antigens. We show here that cross-priming is based on the transfer of proteasome substrates rather than peptides. These findings are potentially important for the rational design of vaccines that elicit CD8 + T cell responses." @default.
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• W2012137725 date "2004-05-28" @default.
• W2012137725 modified "2023-10-13" @default.
• W2012137725 title "CD8⁺T Cell Cross-Priming via Transfer of Proteasome Substrates" @default.
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• W2012137725 doi "https://doi.org/10.1126/science.1096378" @default.
• W2012137725 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15166379" @default.
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