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- W2012140911 abstract "The capacity of blood group antibodies to agglutinate red cells suspended in saline is largely dependent on the antibody isotype. The immunological cross-linking of IgG antibodies has previously been described as a means to increase the reactivity of IgG in many situations. We have prepared anti-D-containing complexes by blending a human IgG anti-D monoclonal antibody (mAb) and a murine anti-human IgG mAb. In standard red cell serology assays, the anti-D complexes exhibited a very high avidity and could agglutinate weak D-positive red cells in direct saline testing. These results indicate that potent saline hemagglutinating reagents of RhD and eventually of other blood group specificities can be prepared from IgG mAbs." @default.
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- W2012140911 date "1993-07-01" @default.
- W2012140911 modified "2023-10-16" @default.
- W2012140911 title "Direct Agglutination of Weak D Red Cells by Tetramolecular Complexes Containing Monoclonal IgG Anti-D" @default.
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- W2012140911 doi "https://doi.org/10.1111/j.1423-0410.1993.tb02131.x" @default.
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