Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012143921> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2012143921 endingPage "300" @default.
- W2012143921 startingPage "293" @default.
- W2012143921 abstract "Direct cell-cell communication through connexin (Cx) complexes is a way to achieve functional accordance of cells within a tissue or an organ. The initial segment (IS), a part of the epididymis, plays important roles in sperm maturation. Steroid hormones influence on expression of a number of genes in the IS of adult animals. However, developmental effect of sex hormones on the gene expression in the IS has not been examined. In this study, estradiol benzoate (EB, an estrogen agonist) or flutamide (Flu, an andevrepogen antagonist) was exogenously administrated at 1 week of postnatal age, and expressional changes of Cx genes in the IS were determined at 4 months of age by a quantitative real-time PCR analysis. Treatment of EB at 0.015 μg/kg body weight (BW) increased expression of Cx30.3, 31.1, and 43 genes. However, treatment of 1.5 μg EB/kg BW resulted in expressional decreases of Cx31, 32, and 45 genes and caused increases of Cx30.3 and 43 gene expression. Significant decreases of Cx31, 31.1, 32, 37, and 45 gene expression were detected with a treatment of 500 μg Flu/kg BW, while expression of Cx43 gene was significantly increased with a treatment of 500 μg Flu/kg BW. A treatment of 50 mg Flu/kg BW led to significant increases of Cx30.3, 32, 37, 40, and 43 gene expression. These findings imply that exogenous exposure of steroidal hormones during the early developmental period would result in aberrant expression of Cx genes in the adult IS." @default.
- W2012143921 created "2016-06-24" @default.
- W2012143921 creator A5046922025 @default.
- W2012143921 date "2014-12-01" @default.
- W2012143921 modified "2023-09-23" @default.
- W2012143921 title "Expressional Modulation of Connexin Isoforms in the Initial Segment of Male Rat treated with Estradiol Benzoate or Flutamide." @default.
- W2012143921 cites W1970643989 @default.
- W2012143921 cites W1975389063 @default.
- W2012143921 cites W1981264454 @default.
- W2012143921 cites W1987926476 @default.
- W2012143921 cites W2002997453 @default.
- W2012143921 cites W2026428103 @default.
- W2012143921 cites W2063936271 @default.
- W2012143921 cites W2090558534 @default.
- W2012143921 cites W2094679825 @default.
- W2012143921 cites W2105047968 @default.
- W2012143921 cites W2166809896 @default.
- W2012143921 cites W2330141368 @default.
- W2012143921 cites W52037872 @default.
- W2012143921 doi "https://doi.org/10.12717/devrep.2014.18.4.293" @default.
- W2012143921 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4415647" @default.
- W2012143921 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25949200" @default.
- W2012143921 hasPublicationYear "2014" @default.
- W2012143921 type Work @default.
- W2012143921 sameAs 2012143921 @default.
- W2012143921 citedByCount "5" @default.
- W2012143921 countsByYear W20121439212015 @default.
- W2012143921 countsByYear W20121439212016 @default.
- W2012143921 crossrefType "journal-article" @default.
- W2012143921 hasAuthorship W2012143921A5046922025 @default.
- W2012143921 hasConcept C104317684 @default.
- W2012143921 hasConcept C121608353 @default.
- W2012143921 hasConcept C126322002 @default.
- W2012143921 hasConcept C134018914 @default.
- W2012143921 hasConcept C150194340 @default.
- W2012143921 hasConcept C158157758 @default.
- W2012143921 hasConcept C16685009 @default.
- W2012143921 hasConcept C2777164284 @default.
- W2012143921 hasConcept C2778313021 @default.
- W2012143921 hasConcept C2778506572 @default.
- W2012143921 hasConcept C2780192828 @default.
- W2012143921 hasConcept C2780228694 @default.
- W2012143921 hasConcept C2781087480 @default.
- W2012143921 hasConcept C2781254305 @default.
- W2012143921 hasConcept C53345823 @default.
- W2012143921 hasConcept C54355233 @default.
- W2012143921 hasConcept C61367390 @default.
- W2012143921 hasConcept C71315377 @default.
- W2012143921 hasConcept C71924100 @default.
- W2012143921 hasConcept C79879829 @default.
- W2012143921 hasConcept C8264082 @default.
- W2012143921 hasConcept C86803240 @default.
- W2012143921 hasConcept C95444343 @default.
- W2012143921 hasConceptScore W2012143921C104317684 @default.
- W2012143921 hasConceptScore W2012143921C121608353 @default.
- W2012143921 hasConceptScore W2012143921C126322002 @default.
- W2012143921 hasConceptScore W2012143921C134018914 @default.
- W2012143921 hasConceptScore W2012143921C150194340 @default.
- W2012143921 hasConceptScore W2012143921C158157758 @default.
- W2012143921 hasConceptScore W2012143921C16685009 @default.
- W2012143921 hasConceptScore W2012143921C2777164284 @default.
- W2012143921 hasConceptScore W2012143921C2778313021 @default.
- W2012143921 hasConceptScore W2012143921C2778506572 @default.
- W2012143921 hasConceptScore W2012143921C2780192828 @default.
- W2012143921 hasConceptScore W2012143921C2780228694 @default.
- W2012143921 hasConceptScore W2012143921C2781087480 @default.
- W2012143921 hasConceptScore W2012143921C2781254305 @default.
- W2012143921 hasConceptScore W2012143921C53345823 @default.
- W2012143921 hasConceptScore W2012143921C54355233 @default.
- W2012143921 hasConceptScore W2012143921C61367390 @default.
- W2012143921 hasConceptScore W2012143921C71315377 @default.
- W2012143921 hasConceptScore W2012143921C71924100 @default.
- W2012143921 hasConceptScore W2012143921C79879829 @default.
- W2012143921 hasConceptScore W2012143921C8264082 @default.
- W2012143921 hasConceptScore W2012143921C86803240 @default.
- W2012143921 hasConceptScore W2012143921C95444343 @default.
- W2012143921 hasIssue "4" @default.
- W2012143921 hasLocation W20121439211 @default.
- W2012143921 hasOpenAccess W2012143921 @default.
- W2012143921 hasPrimaryLocation W20121439211 @default.
- W2012143921 hasRelatedWork W1992132507 @default.
- W2012143921 hasRelatedWork W2012143921 @default.
- W2012143921 hasRelatedWork W2034402330 @default.
- W2012143921 hasRelatedWork W2040045886 @default.
- W2012143921 hasRelatedWork W2064155721 @default.
- W2012143921 hasRelatedWork W2071688816 @default.
- W2012143921 hasRelatedWork W2107474202 @default.
- W2012143921 hasRelatedWork W2137815118 @default.
- W2012143921 hasRelatedWork W2156499301 @default.
- W2012143921 hasRelatedWork W2547826785 @default.
- W2012143921 hasVolume "18" @default.
- W2012143921 isParatext "false" @default.
- W2012143921 isRetracted "false" @default.
- W2012143921 magId "2012143921" @default.
- W2012143921 workType "article" @default.