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• W2012147487 abstract "Vitamin D is of paramount importance to skeletal development, integrity and health. Vitamin D homeostatis is typically deranged in a number of chronic conditions, of which chronic kidney disease is one of the most important. The use of vitamin D based therapy to target secondary hyperparathyroidism is now several decades old, and there is a large body of clinical practice, experience, guidelines and research to underpin this. However, there are many unknowns, of significant clinical relevance. Amongst which is what species of vitamin D we should be using, in what patient, and, under what conditions. Sadly, there has been a real dearth of randomised controlled trials, and trials with outputs of clinical relevance, which means our clinical practice has not developed and refined adequately ove the last 4 decades. This article will discuss the vexed but critical questions of which vitamin D therapies might suit which kidney patients, and will high-light the many important clinical questions which urgently require answering." @default.
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• W2012147487 date "2014-11-01" @default.
• W2012147487 modified "2023-09-29" @default.
• W2012147487 title "The Uses and Abuses of Vitamin D Compounds in Chronic Kidney Disease–Mineral Bone Disease (CKD–MBD)" @default.
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• W2012147487 doi "https://doi.org/10.1016/j.semnephrol.2014.10.002" @default.
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