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- W2012147539 abstract "This paper reports on the presence of prostaglandins E2 (PGE2) and F2alpha (PGF2alpha) in the amniotic fluid, and PG-like material in the venous blood of 10 women during spontaneous abortion at 13-23 weeks gestation. 10 complete amniotic sacs were obtained in addition to 8 other sacs from abdominal treatment of pregnancy on therapeutic grounds. 20 ml of venous blood was taken from 5 of the 10 women and from all 8 women undergoing therapeutic abortion. All 10 samples of amniotic fluid contained high concentrations of PGE2 and PGF2alpha with, in the majority of cases, more PGF2alpha than PGE2. The 8 other specimens of amniotic fluid contained no detectable amounts of PGE2 or PGF2alpha. In the venous blood supply, all 5 exhibited PG-like smooth muscle stimulating activity. The 8 samples from women having therapeutic abortions did not contain any PG-like activity. The finding of PGE2 and PGF2alpha in the amniotic fluid is of interest in view of their potent uterine muscle-stimulating activity. Intravenous infusion of PGE2 and PGF2alpha stimulates the uterus to contract in the 1st and 2nd trimester of pregnancy and can be used for therapeutic abortion." @default.
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- W2012147539 date "1970-09-01" @default.
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- W2012147539 title "PROSTAGLANDINS AND SPONTANEOUS ABORTION" @default.
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- W2012147539 doi "https://doi.org/10.1111/j.1471-0528.1970.tb04410.x" @default.
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