FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012150557> ?p ?o ?g. }

• W2012150557 endingPage "433" @default.
• W2012150557 startingPage "421" @default.
• W2012150557 abstract "Poly(DL-lactic-co-glycolic acid) (PLGA) foams are an osteoconductive support that holds promise for the development of bone tissue in vitro and implantation into orthopedic defects. Because it is desirable that foams maintain their shape and size, we examined a variety of foams cultured in vitro with osteoblastic cells. Foams were prepared with different porosities and pore sizes by the method of solvent casting/porogen leaching using 80, 85, and 90 wt% NaCl sieved with particle sizes of 150–300 and 300–500 µm and characterized by mercury intrusion porosimetry. Foams seeded with cells were found to have volumes after 7 days in static culture that decreased with increasing porosity: the least porous exhibited no change in volume while the most porous foams decreased by 39 ± 10%. In addition, a correlation was observed between decreasing foam volume after 7 days in culture and decreasing internal surface area of the foams prior to seeding. Furthermore, foams prepared with the 300–500 µm porogen had lower porosities, greater mean wall thicknesses between adjacent pores, and larger volumes after 7 days in culture than those prepared with the smaller porogen. Two culture conditions for maintaining cells, static and agitated (in a rotary vessel), were found to have similar influences on foam size, cell density, and osteoblastic function for 7 and 14 days in culture. Finally, we examined unseeded foams in aqueous solutions of pH 3.0, 5.0, and 7.4 and found no significant decrease in foam size with degradation. This study demonstrates that adherent osteoblastic cells may collapse very porous PLGA foams prepared by solvent casting/particulate leaching: a potentially undesirable property for repair of orthopedic defects." @default.
• W2012150557 created "2016-06-24" @default.
• W2012150557 creator A5004603747 @default.
• W2012150557 creator A5013794413 @default.
• W2012150557 creator A5034385466 @default.
• W2012150557 creator A5054147158 @default.
• W2012150557 creator A5059620644 @default.
• W2012150557 date "1999-10-01" @default.
• W2012150557 modified "2023-10-14" @default.
• W2012150557 title "Effect of Osteoblastic Culture Conditions on the Structure of Poly(DL-Lactic-co-Glycolic Acid) Foam Scaffolds" @default.
• W2012150557 cites W1531204382 @default.
• W2012150557 cites W181406011 @default.
• W2012150557 cites W1981034160 @default.
• W2012150557 cites W1991144105 @default.
• W2012150557 cites W2020212801 @default.
• W2012150557 cites W2026811774 @default.
• W2012150557 cites W2031449357 @default.
• W2012150557 cites W2035468113 @default.
• W2012150557 cites W2050141506 @default.
• W2012150557 cites W2057724290 @default.
• W2012150557 cites W2059532050 @default.
• W2012150557 cites W2061134228 @default.
• W2012150557 cites W2067244936 @default.
• W2012150557 cites W2068253453 @default.
• W2012150557 cites W2109441210 @default.
• W2012150557 cites W2109462668 @default.
• W2012150557 cites W2111415695 @default.
• W2012150557 cites W2124383923 @default.
• W2012150557 cites W2347098498 @default.
• W2012150557 cites W2766740219 @default.
• W2012150557 cites W4247013574 @default.
• W2012150557 cites W4251032101 @default.
• W2012150557 doi "https://doi.org/10.1089/ten.1999.5.421" @default.
• W2012150557 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10586098" @default.
• W2012150557 hasPublicationYear "1999" @default.
• W2012150557 type Work @default.
• W2012150557 sameAs 2012150557 @default.
• W2012150557 citedByCount "127" @default.
• W2012150557 countsByYear W20121505572012 @default.
• W2012150557 countsByYear W20121505572013 @default.
• W2012150557 countsByYear W20121505572014 @default.
• W2012150557 countsByYear W20121505572015 @default.
• W2012150557 countsByYear W20121505572016 @default.
• W2012150557 countsByYear W20121505572017 @default.
• W2012150557 countsByYear W20121505572018 @default.
• W2012150557 countsByYear W20121505572019 @default.
• W2012150557 countsByYear W20121505572020 @default.
• W2012150557 countsByYear W20121505572021 @default.
• W2012150557 countsByYear W20121505572022 @default.
• W2012150557 crossrefType "journal-article" @default.
• W2012150557 hasAuthorship W2012150557A5004603747 @default.
• W2012150557 hasAuthorship W2012150557A5013794413 @default.
• W2012150557 hasAuthorship W2012150557A5034385466 @default.
• W2012150557 hasAuthorship W2012150557A5054147158 @default.
• W2012150557 hasAuthorship W2012150557A5059620644 @default.
• W2012150557 hasConcept C121332964 @default.
• W2012150557 hasConcept C127413603 @default.
• W2012150557 hasConcept C136229726 @default.
• W2012150557 hasConcept C155672457 @default.
• W2012150557 hasConcept C159390177 @default.
• W2012150557 hasConcept C159750122 @default.
• W2012150557 hasConcept C159985019 @default.
• W2012150557 hasConcept C171250308 @default.
• W2012150557 hasConcept C178790620 @default.
• W2012150557 hasConcept C185592680 @default.
• W2012150557 hasConcept C187530423 @default.
• W2012150557 hasConcept C192562407 @default.
• W2012150557 hasConcept C20556612 @default.
• W2012150557 hasConcept C2775920511 @default.
• W2012150557 hasConcept C2780165375 @default.
• W2012150557 hasConcept C2780471494 @default.
• W2012150557 hasConcept C2780472526 @default.
• W2012150557 hasConcept C39432304 @default.
• W2012150557 hasConcept C42360764 @default.
• W2012150557 hasConcept C523546767 @default.
• W2012150557 hasConcept C54355233 @default.
• W2012150557 hasConcept C62520636 @default.
• W2012150557 hasConcept C6648577 @default.
• W2012150557 hasConcept C71924100 @default.
• W2012150557 hasConcept C86803240 @default.
• W2012150557 hasConcept C90982505 @default.
• W2012150557 hasConceptScore W2012150557C121332964 @default.
• W2012150557 hasConceptScore W2012150557C127413603 @default.
• W2012150557 hasConceptScore W2012150557C136229726 @default.
• W2012150557 hasConceptScore W2012150557C155672457 @default.
• W2012150557 hasConceptScore W2012150557C159390177 @default.
• W2012150557 hasConceptScore W2012150557C159750122 @default.
• W2012150557 hasConceptScore W2012150557C159985019 @default.
• W2012150557 hasConceptScore W2012150557C171250308 @default.
• W2012150557 hasConceptScore W2012150557C178790620 @default.
• W2012150557 hasConceptScore W2012150557C185592680 @default.
• W2012150557 hasConceptScore W2012150557C187530423 @default.
• W2012150557 hasConceptScore W2012150557C192562407 @default.
• W2012150557 hasConceptScore W2012150557C20556612 @default.
• W2012150557 hasConceptScore W2012150557C2775920511 @default.
• W2012150557 hasConceptScore W2012150557C2780165375 @default.
• W2012150557 hasConceptScore W2012150557C2780471494 @default.
• W2012150557 hasConceptScore W2012150557C2780472526 @default.

• next