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- W2012154535 abstract "Recent studies suggest that whole bone marrow (WBM) derived stem cells may facilitate recovery following myocardial infarction. However, the sub-population of WBM responsible for recovery remains uncertain. By adjusting the abundance of CD34+LinNeg cells in human bone marrow we examined the relative significance of hematopoietic stem cells (HSC) in the recovery of cardiac function in a murine model of induced myocardial infarction. Enrichment of HSC by ~100-fold in WBM transplanted into mice significantly increased recovery of heart function and reduced scar size compared to transplantation of WBM depleted in HSC by ~10-fold (P P P P" @default.
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- W2012154535 date "2013-01-01" @default.
- W2012154535 modified "2023-09-30" @default.
- W2012154535 title "Hematopoietic stem cells are a critical sub-population of whole bone marrow in the treatment of myocardial infarction" @default.
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- W2012154535 doi "https://doi.org/10.4236/scd.2013.32016" @default.
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