FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012156591> ?p ?o ?g. }

• W2012156591 endingPage "1548" @default.
• W2012156591 startingPage "1540" @default.
• W2012156591 abstract "Spontaneous equine recurrent uveitis (ERU) is an incurable autoimmune disease affecting the eye. Identifying biological markers or pathways associated with this disease may allow the understanding of its pathogenesis at a molecular level. The vitreous is the body fluid closest to the disease-affected tissue and possibly also an effector of pathological processes relevant for ERU. Surgical removal of vitreous leads to cessation of relapses in spontaneous uveitis of both man and horse, therefore vitreous composites are likely to contribute to disease progression. Uveitic vitreous is likely to contain potential biomarkers in relatively undiluted quantities. With the goal to identify these markers, we systematically compared vitreous from healthy and disease-affected eyes by proteomic profiling. Nine differentially expressed proteins were identified, that are functionally related to immune response, inflammation, and maintenance of the blood-retinal barrier. One of these, pigment epithelium-derived factor, a protein involved in maintaining a proper blood-retina barrier as well as protecting from neoangiogenesis was additionally found to be down-regulated within uveitic retinal lesions whereas, conversely, vascular endothelial growth factor was found to be up-regulated at these sites. Together, these changes point to as of yet undiscovered biological pathways involved in the pathogenesis of this autoimmune disease." @default.
• W2012156591 created "2016-06-24" @default.
• W2012156591 creator A5009152753 @default.
• W2012156591 creator A5016554378 @default.
• W2012156591 creator A5025441654 @default.
• W2012156591 creator A5045991073 @default.
• W2012156591 creator A5053204551 @default.
• W2012156591 creator A5086062131 @default.
• W2012156591 creator A5089003025 @default.
• W2012156591 date "2007-05-01" @default.
• W2012156591 modified "2023-09-23" @default.
• W2012156591 title "Down-regulation of pigment epithelium-derived factor in uveitic lesion associates with focal vascular endothelial growth factor expression and breakdown of the blood-retinal barrier" @default.
• W2012156591 cites W1497312799 @default.
• W2012156591 cites W1551779607 @default.
• W2012156591 cites W1567559703 @default.
• W2012156591 cites W1940887303 @default.
• W2012156591 cites W1981593008 @default.
• W2012156591 cites W1982265214 @default.
• W2012156591 cites W1983861137 @default.
• W2012156591 cites W1997874250 @default.
• W2012156591 cites W2019661792 @default.
• W2012156591 cites W2026259939 @default.
• W2012156591 cites W2033448975 @default.
• W2012156591 cites W2036977833 @default.
• W2012156591 cites W2048188877 @default.
• W2012156591 cites W2052433403 @default.
• W2012156591 cites W2064577212 @default.
• W2012156591 cites W2074333428 @default.
• W2012156591 cites W2079655276 @default.
• W2012156591 cites W2087746647 @default.
• W2012156591 cites W2094719911 @default.
• W2012156591 cites W2111754541 @default.
• W2012156591 cites W2112215733 @default.
• W2012156591 cites W2112975794 @default.
• W2012156591 cites W2138498116 @default.
• W2012156591 cites W2148232659 @default.
• W2012156591 cites W2154439612 @default.
• W2012156591 cites W2158614841 @default.
• W2012156591 cites W2161672948 @default.
• W2012156591 cites W4239971011 @default.
• W2012156591 cites W77975645 @default.
• W2012156591 doi "https://doi.org/10.1002/pmic.200600795" @default.
• W2012156591 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17407186" @default.
• W2012156591 hasPublicationYear "2007" @default.
• W2012156591 type Work @default.
• W2012156591 sameAs 2012156591 @default.
• W2012156591 citedByCount "50" @default.
• W2012156591 countsByYear W20121565912012 @default.
• W2012156591 countsByYear W20121565912013 @default.
• W2012156591 countsByYear W20121565912014 @default.
• W2012156591 countsByYear W20121565912015 @default.
• W2012156591 countsByYear W20121565912016 @default.
• W2012156591 countsByYear W20121565912018 @default.
• W2012156591 countsByYear W20121565912020 @default.
• W2012156591 countsByYear W20121565912021 @default.
• W2012156591 countsByYear W20121565912022 @default.
• W2012156591 countsByYear W20121565912023 @default.
• W2012156591 crossrefType "journal-article" @default.
• W2012156591 hasAuthorship W2012156591A5009152753 @default.
• W2012156591 hasAuthorship W2012156591A5016554378 @default.
• W2012156591 hasAuthorship W2012156591A5025441654 @default.
• W2012156591 hasAuthorship W2012156591A5045991073 @default.
• W2012156591 hasAuthorship W2012156591A5053204551 @default.
• W2012156591 hasAuthorship W2012156591A5086062131 @default.
• W2012156591 hasAuthorship W2012156591A5089003025 @default.
• W2012156591 hasConcept C134018914 @default.
• W2012156591 hasConcept C142724271 @default.
• W2012156591 hasConcept C167734588 @default.
• W2012156591 hasConcept C169760540 @default.
• W2012156591 hasConcept C203014093 @default.
• W2012156591 hasConcept C2776194053 @default.
• W2012156591 hasConcept C2776914184 @default.
• W2012156591 hasConcept C2777025900 @default.
• W2012156591 hasConcept C2777093970 @default.
• W2012156591 hasConcept C2778024200 @default.
• W2012156591 hasConcept C2778371105 @default.
• W2012156591 hasConcept C2779134260 @default.
• W2012156591 hasConcept C2779829184 @default.
• W2012156591 hasConcept C2780942790 @default.
• W2012156591 hasConcept C502942594 @default.
• W2012156591 hasConcept C555293320 @default.
• W2012156591 hasConcept C71924100 @default.
• W2012156591 hasConcept C86803240 @default.
• W2012156591 hasConceptScore W2012156591C134018914 @default.
• W2012156591 hasConceptScore W2012156591C142724271 @default.
• W2012156591 hasConceptScore W2012156591C167734588 @default.
• W2012156591 hasConceptScore W2012156591C169760540 @default.
• W2012156591 hasConceptScore W2012156591C203014093 @default.
• W2012156591 hasConceptScore W2012156591C2776194053 @default.
• W2012156591 hasConceptScore W2012156591C2776914184 @default.
• W2012156591 hasConceptScore W2012156591C2777025900 @default.
• W2012156591 hasConceptScore W2012156591C2777093970 @default.
• W2012156591 hasConceptScore W2012156591C2778024200 @default.
• W2012156591 hasConceptScore W2012156591C2778371105 @default.
• W2012156591 hasConceptScore W2012156591C2779134260 @default.
• W2012156591 hasConceptScore W2012156591C2779829184 @default.
• W2012156591 hasConceptScore W2012156591C2780942790 @default.
• W2012156591 hasConceptScore W2012156591C502942594 @default.

• next