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- W2012157296 abstract "Eosinophilic granulomatosis with polyangiitis (EGPA) is a systemic eosinophilic vasculitis, belonging to the group of ANCA-associated vasculitides (AAV). EGPA pathogenesis is still elusive, but a potential role for IL-5 and Eotaxins mediated eosinophil activation has been reported. Imatinib mesylate, a tyrosine kinase (TK) inhibitor, is approved for the treatment of chronic myeloid leukaemia and FIP1L1/PDGFRA positive gene fusion hypereosinophilia. A potential role for imatinib in the treatment of idiopathic hypereosinophilic syndrome (HES) and AAV has been recently proposed." @default.
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- W2012157296 date "2015-01-01" @default.
- W2012157296 modified "2023-09-27" @default.
- W2012157296 title "Is there a role for imatinib mesylate in the treatment of eosinophilic granulomatosis with polyangiitis?" @default.
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- W2012157296 doi "https://doi.org/10.1016/j.jbspin.2014.06.004" @default.
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