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- W2012162297 abstract "In this study we investigated the effect of Listeria monocytogenes infection on the activation of the Raf-MEK-MAP kinase pathway in eukaryotic host cells. HeLa cell infection with L. monocytogenes EGD resulted in a rapid, but transient, phosphorylation of the MAP kinases erk-1 and erk-2, a transient phosphorylation of the MAP kinase kinase MEK-1, and a transient activation of the MAP kinase kinase kinase Raf. In parallel to the transient phosphorylation of the MAP kinases, we detected induced expression of the MAP kinase phosphatase MKP-1. Additionally we present evidence that listeriolysin O is the inducing agent for activation of the Raf-MEK-MAP kinase pathway." @default.
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- W2012162297 date "2006-01-17" @default.
- W2012162297 modified "2023-09-27" @default.
- W2012162297 title "Listeria monocytogenes infection of HeLa cells results in listeriolysinO-mediated transient activation of the Raf-MEK-MAP kinase pathway" @default.
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- W2012162297 doi "https://doi.org/10.1111/j.1574-6968.1997.tb10287.x" @default.
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