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• W2012165192 abstract "Enzyme immunoassays were developed to measure immunoglobulin G (IgG) and IgG1-4 subclass antibodies to pneumococcal capsular polysaccharides (PCP) types 4 and 7F. In healthy subjects, anti-PCP antibodies were predominately of the IgG1 and IgG2 subclasses. There was a significant increase in IgG, IgG1, and IgG2 anti-PCP antibody concentrations following immunization with pneumococcal vaccine. IgG and IgG2, but not IgG1, anti-PCP antibody concentrations correlated with total anti-PCP antibody concentrations measured by the standard radioimmunoassay and with serum opsonic activity for serotype 7F Streptococcus pneumoniae. Such IgG and IgG subclass antigen-specific antibody assays may be useful to investigate the immune response to pneumococcal polysaccharides." @default.
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• W2012165192 date "1987-07-01" @default.
• W2012165192 modified "2023-09-23" @default.
• W2012165192 title "Immunoglobulin G class and subclass antibodies to pneumococcal capsular polysaccharides" @default.
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• W2012165192 doi "https://doi.org/10.1016/0090-1229(87)90057-2" @default.
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