Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012166019> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2012166019 endingPage "224" @default.
- W2012166019 startingPage "220" @default.
- W2012166019 abstract "Only male zebra finches sing and several telencephalic song control regions exhibit sex differences in neuron number that presumably reflect effects of estrogen (E2) exerted during the first few posthatch weeks. That is, implanting females with E2 during this time masculinizes neuron number and instills the capacity for vocal behavior. In certain song regions, E2 masculinizes neuron number by preventing the naturally-occurring death of neurons, long after their production, migration and process outgrowth are complete. However, in the Higher Vocal Center (HVC), the cellular mechanisms by which E2 establishes sex differences in neuron number are poorly understood. In contrast with other song regions, HVC neurogenesis overlaps with sexual differentiation and the incorporation of new neurons is greater in young males and E2-treated females, than in normal females. However, it is not known whether E2 promotes the addition of HVC neurons by stimulating their production, specification, and/or survival. To address this issue we injected males and females with [3H]thymidine on days 15 and 16 to label a small group of sexually dimorphic HVC neuronal cohorts born during sexual differentiation. Afterwards, on day 17, females were implanted with Silastic pellets filled with estradiol benzoate (EB) or left empty. We report here that EB exposure on day 17 masculinized (increased) the number of neurons in the HVC at day 35 that were labeled by [3H]thymidine injections on days 15/16. Thus, EB was able to increase cell number among at least some HVC neuronal cohorts after their final division, implying estrogenic regulation of post-mitotic events. When viewed with other studies that have examined the development of sex differences in the HVC, our results suggest that during sexual differentiation E2 promotes the specification and/or early survival of HVC neurons." @default.
- W2012166019 created "2016-06-24" @default.
- W2012166019 creator A5026097980 @default.
- W2012166019 creator A5032032475 @default.
- W2012166019 creator A5057109092 @default.
- W2012166019 date "1995-04-01" @default.
- W2012166019 modified "2023-09-25" @default.
- W2012166019 title "Estrogen promotes neuron addition to an avian song-control nucleus by regulating post-mitotic events" @default.
- W2012166019 cites W1559620581 @default.
- W2012166019 cites W1964607223 @default.
- W2012166019 cites W1995180942 @default.
- W2012166019 cites W1999301655 @default.
- W2012166019 cites W2017032811 @default.
- W2012166019 cites W2023590745 @default.
- W2012166019 cites W2035077777 @default.
- W2012166019 cites W2035871570 @default.
- W2012166019 cites W2052844486 @default.
- W2012166019 cites W2060495631 @default.
- W2012166019 cites W2061053248 @default.
- W2012166019 cites W2064377090 @default.
- W2012166019 cites W2070172938 @default.
- W2012166019 cites W2073098472 @default.
- W2012166019 cites W2089616328 @default.
- W2012166019 cites W2108307116 @default.
- W2012166019 cites W2116721703 @default.
- W2012166019 cites W2170750276 @default.
- W2012166019 doi "https://doi.org/10.1016/0165-3806(94)00215-l" @default.
- W2012166019 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7600669" @default.
- W2012166019 hasPublicationYear "1995" @default.
- W2012166019 type Work @default.
- W2012166019 sameAs 2012166019 @default.
- W2012166019 citedByCount "63" @default.
- W2012166019 countsByYear W20121660192012 @default.
- W2012166019 countsByYear W20121660192013 @default.
- W2012166019 countsByYear W20121660192014 @default.
- W2012166019 countsByYear W20121660192015 @default.
- W2012166019 countsByYear W20121660192017 @default.
- W2012166019 countsByYear W20121660192020 @default.
- W2012166019 crossrefType "journal-article" @default.
- W2012166019 hasAuthorship W2012166019A5026097980 @default.
- W2012166019 hasAuthorship W2012166019A5032032475 @default.
- W2012166019 hasAuthorship W2012166019A5057109092 @default.
- W2012166019 hasBestOaLocation W20121660191 @default.
- W2012166019 hasConcept C104317684 @default.
- W2012166019 hasConcept C126322002 @default.
- W2012166019 hasConcept C134018914 @default.
- W2012166019 hasConcept C169760540 @default.
- W2012166019 hasConcept C2777164284 @default.
- W2012166019 hasConcept C2778794669 @default.
- W2012166019 hasConcept C2780723820 @default.
- W2012166019 hasConcept C4746552 @default.
- W2012166019 hasConcept C54355233 @default.
- W2012166019 hasConcept C63405245 @default.
- W2012166019 hasConcept C71924100 @default.
- W2012166019 hasConcept C86803240 @default.
- W2012166019 hasConcept C93304396 @default.
- W2012166019 hasConcept C95444343 @default.
- W2012166019 hasConceptScore W2012166019C104317684 @default.
- W2012166019 hasConceptScore W2012166019C126322002 @default.
- W2012166019 hasConceptScore W2012166019C134018914 @default.
- W2012166019 hasConceptScore W2012166019C169760540 @default.
- W2012166019 hasConceptScore W2012166019C2777164284 @default.
- W2012166019 hasConceptScore W2012166019C2778794669 @default.
- W2012166019 hasConceptScore W2012166019C2780723820 @default.
- W2012166019 hasConceptScore W2012166019C4746552 @default.
- W2012166019 hasConceptScore W2012166019C54355233 @default.
- W2012166019 hasConceptScore W2012166019C63405245 @default.
- W2012166019 hasConceptScore W2012166019C71924100 @default.
- W2012166019 hasConceptScore W2012166019C86803240 @default.
- W2012166019 hasConceptScore W2012166019C93304396 @default.
- W2012166019 hasConceptScore W2012166019C95444343 @default.
- W2012166019 hasIssue "2" @default.
- W2012166019 hasLocation W20121660191 @default.
- W2012166019 hasLocation W20121660192 @default.
- W2012166019 hasOpenAccess W2012166019 @default.
- W2012166019 hasPrimaryLocation W20121660191 @default.
- W2012166019 hasRelatedWork W1978736710 @default.
- W2012166019 hasRelatedWork W1986969712 @default.
- W2012166019 hasRelatedWork W1995647897 @default.
- W2012166019 hasRelatedWork W2012166019 @default.
- W2012166019 hasRelatedWork W2013481652 @default.
- W2012166019 hasRelatedWork W2055397537 @default.
- W2012166019 hasRelatedWork W2090461312 @default.
- W2012166019 hasRelatedWork W2101821182 @default.
- W2012166019 hasRelatedWork W2109882125 @default.
- W2012166019 hasRelatedWork W2168803779 @default.
- W2012166019 hasVolume "85" @default.
- W2012166019 isParatext "false" @default.
- W2012166019 isRetracted "false" @default.
- W2012166019 magId "2012166019" @default.
- W2012166019 workType "article" @default.