Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012167946> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2012167946 endingPage "203" @default.
- W2012167946 startingPage "198" @default.
- W2012167946 abstract "The effects of electrolytic lesions of the locus coeruleus (LC) on endogenous octopamine and noradrenaline levels were observed at various temporal intervals. Noradrenaline was assayed from halved tissue samples by high-performance liquid chromatography (HPLC) while octopamine was determined from the other halfs of the brain samples by radioenzymatic assay methods accompanied by chromatographic separation. Brains were dissected into 8 regions: cerebellum, anterior and posterior cortex, hippocampus, hypothalamus, medulla/pons, midbrain and striatum. Assays were performed at postlesion intervals of 4, 8, 13 and 18 days. The rates of depletion of noradrenaline at the tested intervals roughly matched those of octopamine in the anterior cortex, posterior cortex and striatum. In the cerebellum, hypothalamus, hippocampus and pons/medulla, levels of octopamine diminished later than those of noradrenaline, at times showing an initial increase within the first week after LC lesion. In the midbrain however, this pattern was reversed, octopamine levels initially decreasing in parallel with noradrenaline but subsequently recovering to significantly higher values. The results do not unequivocally support the hypothesis that octopamine is present in the brain solely as a ‘false transmitter’ in noradrenergic neurones. Neither, however, do they provide clear support for earlier contentions that octopamine is likely to play a role in central neurones as a synaptic transmitter, independent of the noradrenergic system." @default.
- W2012167946 created "2016-06-24" @default.
- W2012167946 creator A5053217139 @default.
- W2012167946 creator A5053831232 @default.
- W2012167946 creator A5066663472 @default.
- W2012167946 creator A5072422708 @default.
- W2012167946 date "1976-04-01" @default.
- W2012167946 modified "2023-09-27" @default.
- W2012167946 title "Serial changes in norepinephrine and dopamine in rat brain after locus coeruleus lesions" @default.
- W2012167946 cites W1238819995 @default.
- W2012167946 cites W2000708767 @default.
- W2012167946 cites W2003034802 @default.
- W2012167946 cites W2007803760 @default.
- W2012167946 cites W2011002177 @default.
- W2012167946 cites W2020839664 @default.
- W2012167946 cites W2033505977 @default.
- W2012167946 cites W2049780980 @default.
- W2012167946 cites W2063258576 @default.
- W2012167946 cites W2081725037 @default.
- W2012167946 cites W2083029215 @default.
- W2012167946 cites W2085547682 @default.
- W2012167946 cites W2113449040 @default.
- W2012167946 cites W2493885984 @default.
- W2012167946 doi "https://doi.org/10.1016/0006-8993(76)90087-1" @default.
- W2012167946 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1268709" @default.
- W2012167946 hasPublicationYear "1976" @default.
- W2012167946 type Work @default.
- W2012167946 sameAs 2012167946 @default.
- W2012167946 citedByCount "25" @default.
- W2012167946 crossrefType "journal-article" @default.
- W2012167946 hasAuthorship W2012167946A5053217139 @default.
- W2012167946 hasAuthorship W2012167946A5053831232 @default.
- W2012167946 hasAuthorship W2012167946A5066663472 @default.
- W2012167946 hasAuthorship W2012167946A5072422708 @default.
- W2012167946 hasConcept C126322002 @default.
- W2012167946 hasConcept C134018914 @default.
- W2012167946 hasConcept C169760540 @default.
- W2012167946 hasConcept C170493617 @default.
- W2012167946 hasConcept C185592680 @default.
- W2012167946 hasConcept C2775864247 @default.
- W2012167946 hasConcept C2775894120 @default.
- W2012167946 hasConcept C2777003273 @default.
- W2012167946 hasConcept C2778468602 @default.
- W2012167946 hasConcept C2778514916 @default.
- W2012167946 hasConcept C2778897929 @default.
- W2012167946 hasConcept C2779652256 @default.
- W2012167946 hasConcept C2780062018 @default.
- W2012167946 hasConcept C2780696224 @default.
- W2012167946 hasConcept C2781161787 @default.
- W2012167946 hasConcept C513476851 @default.
- W2012167946 hasConcept C529278444 @default.
- W2012167946 hasConcept C552161191 @default.
- W2012167946 hasConcept C71924100 @default.
- W2012167946 hasConcept C86803240 @default.
- W2012167946 hasConceptScore W2012167946C126322002 @default.
- W2012167946 hasConceptScore W2012167946C134018914 @default.
- W2012167946 hasConceptScore W2012167946C169760540 @default.
- W2012167946 hasConceptScore W2012167946C170493617 @default.
- W2012167946 hasConceptScore W2012167946C185592680 @default.
- W2012167946 hasConceptScore W2012167946C2775864247 @default.
- W2012167946 hasConceptScore W2012167946C2775894120 @default.
- W2012167946 hasConceptScore W2012167946C2777003273 @default.
- W2012167946 hasConceptScore W2012167946C2778468602 @default.
- W2012167946 hasConceptScore W2012167946C2778514916 @default.
- W2012167946 hasConceptScore W2012167946C2778897929 @default.
- W2012167946 hasConceptScore W2012167946C2779652256 @default.
- W2012167946 hasConceptScore W2012167946C2780062018 @default.
- W2012167946 hasConceptScore W2012167946C2780696224 @default.
- W2012167946 hasConceptScore W2012167946C2781161787 @default.
- W2012167946 hasConceptScore W2012167946C513476851 @default.
- W2012167946 hasConceptScore W2012167946C529278444 @default.
- W2012167946 hasConceptScore W2012167946C552161191 @default.
- W2012167946 hasConceptScore W2012167946C71924100 @default.
- W2012167946 hasConceptScore W2012167946C86803240 @default.
- W2012167946 hasIssue "1" @default.
- W2012167946 hasLocation W20121679461 @default.
- W2012167946 hasLocation W20121679462 @default.
- W2012167946 hasOpenAccess W2012167946 @default.
- W2012167946 hasPrimaryLocation W20121679461 @default.
- W2012167946 hasRelatedWork W133648661 @default.
- W2012167946 hasRelatedWork W1978175539 @default.
- W2012167946 hasRelatedWork W1993002249 @default.
- W2012167946 hasRelatedWork W2041107699 @default.
- W2012167946 hasRelatedWork W2053203668 @default.
- W2012167946 hasRelatedWork W2086343781 @default.
- W2012167946 hasRelatedWork W2087931899 @default.
- W2012167946 hasRelatedWork W2089103608 @default.
- W2012167946 hasRelatedWork W2246813284 @default.
- W2012167946 hasRelatedWork W2340603067 @default.
- W2012167946 hasVolume "106" @default.
- W2012167946 isParatext "false" @default.
- W2012167946 isRetracted "false" @default.
- W2012167946 magId "2012167946" @default.
- W2012167946 workType "article" @default.