Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012169295> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2012169295 endingPage "600" @default.
- W2012169295 startingPage "595" @default.
- W2012169295 abstract "Three oligonucleotide primer combinations selected from the 5' noncoding, the nucleocapsid and the putative nonstructural regions of the hepatitis C virus genome were compared in a nested polymerase chain reaction assay with respect to sensitivity and specificity for the detection of viral RNA in chimpanzee-infected and human-infected sera. Sera from both the acute and the chronic phase of the infection were obtained from 13 animals inoculated with five different non-A, non-B hepatitis strains and from seven cardiac surgery patients who had non-A, non-B hepatitis develop after transfusion and who had been tested in parallel for the presence of hepatitis C virus RNA and anti-C 100-3. A total of 90% of the acute-phase and 100% of the chronic-phase sera tested positive for hepatitis C virus RNA when the 5' noncoding-derived or the nucleocapsid-derived combinations were used; only 58% and 56%, respectively, gave positive results with the putative nonstructural primers, whereas 33% and 71%, respectively, scored positive for C100-3. Thus polymerase chain reaction primers selected from either the highly conserved 5' noncoding or nucleocapsid-regions appear to provide the sensitivity and the specificity necessary to detect low levels of hepatitis C virus RNA in both chimpanzee-infected and human-infected sera." @default.
- W2012169295 created "2016-06-24" @default.
- W2012169295 creator A5006068229 @default.
- W2012169295 creator A5026293971 @default.
- W2012169295 creator A5032827289 @default.
- W2012169295 creator A5034090271 @default.
- W2012169295 creator A5052583987 @default.
- W2012169295 date "1991-10-01" @default.
- W2012169295 modified "2023-10-16" @default.
- W2012169295 title "Use of conserved sequences from hepatitis C virus for the detection of viral RNA in infected sera by polymerase chain reaction" @default.
- W2012169295 cites W1517480469 @default.
- W2012169295 cites W1667513272 @default.
- W2012169295 cites W1932939055 @default.
- W2012169295 cites W1974879228 @default.
- W2012169295 cites W1998621721 @default.
- W2012169295 cites W2004419588 @default.
- W2012169295 cites W2006309458 @default.
- W2012169295 cites W2022878150 @default.
- W2012169295 cites W2027655764 @default.
- W2012169295 cites W2027673360 @default.
- W2012169295 cites W2043019442 @default.
- W2012169295 cites W2066124462 @default.
- W2012169295 cites W2088783470 @default.
- W2012169295 cites W2090915231 @default.
- W2012169295 cites W2092868217 @default.
- W2012169295 cites W2093155194 @default.
- W2012169295 cites W2094028456 @default.
- W2012169295 cites W2095447086 @default.
- W2012169295 cites W2123135658 @default.
- W2012169295 cites W2155808129 @default.
- W2012169295 cites W2163131045 @default.
- W2012169295 cites W2165837877 @default.
- W2012169295 cites W2179658561 @default.
- W2012169295 cites W2320111967 @default.
- W2012169295 cites W2333434124 @default.
- W2012169295 doi "https://doi.org/10.1002/hep.1840140404" @default.
- W2012169295 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1655606" @default.
- W2012169295 hasPublicationYear "1991" @default.
- W2012169295 type Work @default.
- W2012169295 sameAs 2012169295 @default.
- W2012169295 citedByCount "77" @default.
- W2012169295 crossrefType "journal-article" @default.
- W2012169295 hasAuthorship W2012169295A5006068229 @default.
- W2012169295 hasAuthorship W2012169295A5026293971 @default.
- W2012169295 hasAuthorship W2012169295A5032827289 @default.
- W2012169295 hasAuthorship W2012169295A5034090271 @default.
- W2012169295 hasAuthorship W2012169295A5052583987 @default.
- W2012169295 hasBestOaLocation W20121692951 @default.
- W2012169295 hasConcept C104317684 @default.
- W2012169295 hasConcept C153911025 @default.
- W2012169295 hasConcept C157431215 @default.
- W2012169295 hasConcept C159047783 @default.
- W2012169295 hasConcept C178790620 @default.
- W2012169295 hasConcept C185592680 @default.
- W2012169295 hasConcept C194575299 @default.
- W2012169295 hasConcept C2522874641 @default.
- W2012169295 hasConcept C2776408679 @default.
- W2012169295 hasConcept C2777563447 @default.
- W2012169295 hasConcept C49105822 @default.
- W2012169295 hasConcept C54355233 @default.
- W2012169295 hasConcept C67705224 @default.
- W2012169295 hasConcept C82381507 @default.
- W2012169295 hasConcept C86803240 @default.
- W2012169295 hasConceptScore W2012169295C104317684 @default.
- W2012169295 hasConceptScore W2012169295C153911025 @default.
- W2012169295 hasConceptScore W2012169295C157431215 @default.
- W2012169295 hasConceptScore W2012169295C159047783 @default.
- W2012169295 hasConceptScore W2012169295C178790620 @default.
- W2012169295 hasConceptScore W2012169295C185592680 @default.
- W2012169295 hasConceptScore W2012169295C194575299 @default.
- W2012169295 hasConceptScore W2012169295C2522874641 @default.
- W2012169295 hasConceptScore W2012169295C2776408679 @default.
- W2012169295 hasConceptScore W2012169295C2777563447 @default.
- W2012169295 hasConceptScore W2012169295C49105822 @default.
- W2012169295 hasConceptScore W2012169295C54355233 @default.
- W2012169295 hasConceptScore W2012169295C67705224 @default.
- W2012169295 hasConceptScore W2012169295C82381507 @default.
- W2012169295 hasConceptScore W2012169295C86803240 @default.
- W2012169295 hasIssue "4" @default.
- W2012169295 hasLocation W20121692951 @default.
- W2012169295 hasLocation W20121692952 @default.
- W2012169295 hasOpenAccess W2012169295 @default.
- W2012169295 hasPrimaryLocation W20121692951 @default.
- W2012169295 hasRelatedWork W1160187515 @default.
- W2012169295 hasRelatedWork W2019810109 @default.
- W2012169295 hasRelatedWork W2053464542 @default.
- W2012169295 hasRelatedWork W2054848430 @default.
- W2012169295 hasRelatedWork W2056420846 @default.
- W2012169295 hasRelatedWork W2065613110 @default.
- W2012169295 hasRelatedWork W2080326260 @default.
- W2012169295 hasRelatedWork W2142935324 @default.
- W2012169295 hasRelatedWork W2416773140 @default.
- W2012169295 hasRelatedWork W2461718593 @default.
- W2012169295 hasVolume "14" @default.
- W2012169295 isParatext "false" @default.
- W2012169295 isRetracted "false" @default.
- W2012169295 magId "2012169295" @default.
- W2012169295 workType "article" @default.