FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012171640> ?p ?o ?g. }

• W2012171640 endingPage "156" @default.
• W2012171640 startingPage "151" @default.
• W2012171640 abstract "Background: Polycystic ovary syndrome (PCOS) is characterized by hyperandrogenism and menstrual disturbance. Independent of the presence of obesity, these women are frequently insulin resistant and, therefore, hyperinsulinemia, which appears to play a pathogenic role in the disease. Administration of insulin-sensitizing drugs, such as metformin and rosiglitazone, increase ovulation rates and decrease circulating androgens. Objective: The aim of this study was to evaluate the effects of rosiglitazone with or without clomiphene citrate (CC) on ovulation in patients with PCOS. Methods: A randomized, prospective study was carried out on 30 women with PCOS. Subjects in group 1 (n = 15) received rosiglitazone 4 mg BID and subjects in group 2 (n = 15) received rosiglitazone 4 mg BID with CC 50 mg on cycle days 5–9. The duration of treatment was 3 months. Main Outcome Measures: The primary outcome was ovulation as defined by serum progesterone >5 ng/mL on day 24 of the cycle. Secondary outcomes were pregnancy and changes in serum luteinizing hormone (LH), LH follicle-stimulating hormone (FSH) ratio, fasting serum glucose, testosterone, and lipid profile levels. Results: In this study, rosiglitazone was effective in inducing ovulation of 6 of 15 patients (40%) in group 1 and 10 of 15 (66.67%) in group 2. Three (3) patients in group 1 (20%) and 6 patients in group 2 (40%) became pregnant. There was also a decrease in LH hormone and the LH:FSH ratio in both the groups (p < 0.01). Conclusions: Rosiglitazone with or without clomiphene changes endocrine markers in PCOS and improves ovulation and pregnancy rate. (J GYNECOL SURG 22:151)" @default.
• W2012171640 created "2016-06-24" @default.
• W2012171640 creator A5040460446 @default.
• W2012171640 creator A5044215274 @default.
• W2012171640 creator A5061422706 @default.
• W2012171640 creator A5071444659 @default.
• W2012171640 date "2006-12-01" @default.
• W2012171640 modified "2023-10-16" @default.
• W2012171640 title "Effect of Rosiglitazone in Spontaneous and Clomiphene Citrate–Induced Ovulation in Women with Polycystic Ovary Syndrome" @default.
• W2012171640 cites W1554188337 @default.
• W2012171640 cites W1801767415 @default.
• W2012171640 cites W1946263363 @default.
• W2012171640 cites W1980513306 @default.
• W2012171640 cites W1989901309 @default.
• W2012171640 cites W2011801069 @default.
• W2012171640 cites W2019937567 @default.
• W2012171640 cites W2022541947 @default.
• W2012171640 cites W2036174062 @default.
• W2012171640 cites W2055047352 @default.
• W2012171640 cites W2056664245 @default.
• W2012171640 cites W2080945946 @default.
• W2012171640 cites W2081568627 @default.
• W2012171640 cites W2096257807 @default.
• W2012171640 cites W2109580294 @default.
• W2012171640 cites W2118313918 @default.
• W2012171640 cites W2123925343 @default.
• W2012171640 cites W2127258766 @default.
• W2012171640 cites W2137615975 @default.
• W2012171640 cites W2164028234 @default.
• W2012171640 cites W2438030946 @default.
• W2012171640 cites W4253259014 @default.
• W2012171640 doi "https://doi.org/10.1089/gyn.2006.22.151" @default.
• W2012171640 hasPublicationYear "2006" @default.
• W2012171640 type Work @default.
• W2012171640 sameAs 2012171640 @default.
• W2012171640 citedByCount "0" @default.
• W2012171640 crossrefType "journal-article" @default.
• W2012171640 hasAuthorship W2012171640A5040460446 @default.
• W2012171640 hasAuthorship W2012171640A5044215274 @default.
• W2012171640 hasAuthorship W2012171640A5061422706 @default.
• W2012171640 hasAuthorship W2012171640A5071444659 @default.
• W2012171640 hasConcept C126322002 @default.
• W2012171640 hasConcept C134018914 @default.
• W2012171640 hasConcept C2777391703 @default.
• W2012171640 hasConcept C2777688143 @default.
• W2012171640 hasConcept C2777702977 @default.
• W2012171640 hasConcept C2778575703 @default.
• W2012171640 hasConcept C2778641792 @default.
• W2012171640 hasConcept C2779234561 @default.
• W2012171640 hasConcept C2779279991 @default.
• W2012171640 hasConcept C2779306644 @default.
• W2012171640 hasConcept C2780152017 @default.
• W2012171640 hasConcept C2780186808 @default.
• W2012171640 hasConcept C2780323712 @default.
• W2012171640 hasConcept C2780853582 @default.
• W2012171640 hasConcept C2781230225 @default.
• W2012171640 hasConcept C3018442814 @default.
• W2012171640 hasConcept C54355233 @default.
• W2012171640 hasConcept C71315377 @default.
• W2012171640 hasConcept C71924100 @default.
• W2012171640 hasConcept C86803240 @default.
• W2012171640 hasConceptScore W2012171640C126322002 @default.
• W2012171640 hasConceptScore W2012171640C134018914 @default.
• W2012171640 hasConceptScore W2012171640C2777391703 @default.
• W2012171640 hasConceptScore W2012171640C2777688143 @default.
• W2012171640 hasConceptScore W2012171640C2777702977 @default.
• W2012171640 hasConceptScore W2012171640C2778575703 @default.
• W2012171640 hasConceptScore W2012171640C2778641792 @default.
• W2012171640 hasConceptScore W2012171640C2779234561 @default.
• W2012171640 hasConceptScore W2012171640C2779279991 @default.
• W2012171640 hasConceptScore W2012171640C2779306644 @default.
• W2012171640 hasConceptScore W2012171640C2780152017 @default.
• W2012171640 hasConceptScore W2012171640C2780186808 @default.
• W2012171640 hasConceptScore W2012171640C2780323712 @default.
• W2012171640 hasConceptScore W2012171640C2780853582 @default.
• W2012171640 hasConceptScore W2012171640C2781230225 @default.
• W2012171640 hasConceptScore W2012171640C3018442814 @default.
• W2012171640 hasConceptScore W2012171640C54355233 @default.
• W2012171640 hasConceptScore W2012171640C71315377 @default.
• W2012171640 hasConceptScore W2012171640C71924100 @default.
• W2012171640 hasConceptScore W2012171640C86803240 @default.
• W2012171640 hasIssue "4" @default.
• W2012171640 hasLocation W20121716401 @default.
• W2012171640 hasOpenAccess W2012171640 @default.
• W2012171640 hasPrimaryLocation W20121716401 @default.
• W2012171640 hasRelatedWork W2010241090 @default.
• W2012171640 hasRelatedWork W2057951236 @default.
• W2012171640 hasRelatedWork W2067460231 @default.
• W2012171640 hasRelatedWork W2117962489 @default.
• W2012171640 hasRelatedWork W2123925343 @default.
• W2012171640 hasRelatedWork W2268306004 @default.
• W2012171640 hasRelatedWork W2619026818 @default.
• W2012171640 hasRelatedWork W2972707368 @default.
• W2012171640 hasRelatedWork W3028872866 @default.
• W2012171640 hasRelatedWork W44640728 @default.
• W2012171640 hasVolume "22" @default.
• W2012171640 isParatext "false" @default.
• W2012171640 isRetracted "false" @default.

• next