FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012176405> ?p ?o ?g. }

• W2012176405 endingPage "810" @default.
• W2012176405 startingPage "803" @default.
• W2012176405 abstract "Background/Aim. Insulin resistance is related to accelerated atherosclerosis, whereas weight loss is associated with the increasing insulin sensitivity, the improvement of functional and the morphological parameters of arterial circulation, and the reduction of cardiovascular morbidity and mortality. The aim of our study was to evaluate the influence of orlistat treatment on serum insulin level and functional and morphologic parameters of peripheral arterial circulation. Methods. We conducted a prospective, randomized, double ? blind, placebo ? controlled study. Thirty patients with body mass index over 30 kg/m2 normotensive, nonsmokers, without clinically manifested cardiovascular disease or diabetes were randomly assigned either orlistat (120 mg, 3 times daily; n = 20) or placebo (n = 10) in a double ? blind manner. All of the patients were on individually calculated hypocaloric diet. The follow-up period was 24 weeks. Arterial pressure, fasting serum glucose and insulin level, triglycerides, total cholesterol and low density lipoprotein-cholesterol were determined at the beginning, following 3 and 6 months. Also, the intima ? media thickness of right superficial femoral artery and the mean blood flow velocity were determined with ultrasonography. Results. Inside the period of 3 and 6 months, there were the greater reductions of body mass index, arterial pressure, fasting glucose and insulin level, total cholesterol, low density lipoproteins, as well as the greater reductions of mean velocity blood flow and peripheral pulse pressure in the orlistat group vs the placebo group (p < 0.01). Greater reductions in the waist circumference and intima ? media thickness were registered following 6 months in the orlistat vs the placebo group (p < 0.01). Conclusion. In the group of obese patients orlistat therapy reduced risk factors, serum insulin level and improved early arterial functional changes as assessed with the reductions of the mean velocity blood flow and peripheral pulse pressure following 3 months. The regression of morphological changes, as assessed with the reduction in intima ? media thickness, was feasible over the six ? month period." @default.
• W2012176405 created "2016-06-24" @default.
• W2012176405 creator A5041422883 @default.
• W2012176405 creator A5044854052 @default.
• W2012176405 creator A5062083658 @default.
• W2012176405 creator A5074614794 @default.
• W2012176405 date "2005-01-01" @default.
• W2012176405 modified "2023-10-14" @default.
• W2012176405 title "Influence of orlistat therapy on serum insulin level and morphological and functional parameters of peripheral arterial circulation in obese patients" @default.
• W2012176405 cites W1965697065 @default.
• W2012176405 cites W1970652218 @default.
• W2012176405 cites W1971066944 @default.
• W2012176405 cites W1978021168 @default.
• W2012176405 cites W1981444005 @default.
• W2012176405 cites W1987746625 @default.
• W2012176405 cites W1992965014 @default.
• W2012176405 cites W1993800499 @default.
• W2012176405 cites W2002048323 @default.
• W2012176405 cites W2008791277 @default.
• W2012176405 cites W2009788323 @default.
• W2012176405 cites W2016006793 @default.
• W2012176405 cites W2021976026 @default.
• W2012176405 cites W2023731005 @default.
• W2012176405 cites W2044481780 @default.
• W2012176405 cites W2048083913 @default.
• W2012176405 cites W2051862140 @default.
• W2012176405 cites W2052035619 @default.
• W2012176405 cites W2072690400 @default.
• W2012176405 cites W2077997765 @default.
• W2012176405 cites W2085097428 @default.
• W2012176405 cites W2091455808 @default.
• W2012176405 cites W2092705725 @default.
• W2012176405 cites W2095623476 @default.
• W2012176405 cites W2097843221 @default.
• W2012176405 cites W2102170193 @default.
• W2012176405 cites W2115657895 @default.
• W2012176405 cites W2125288612 @default.
• W2012176405 cites W2130897958 @default.
• W2012176405 cites W2132275455 @default.
• W2012176405 cites W2132930967 @default.
• W2012176405 cites W2134459221 @default.
• W2012176405 cites W2134860420 @default.
• W2012176405 cites W2136851633 @default.
• W2012176405 cites W2142687288 @default.
• W2012176405 cites W2152037109 @default.
• W2012176405 cites W2157135485 @default.
• W2012176405 cites W2159793865 @default.
• W2012176405 cites W2170696534 @default.
• W2012176405 cites W2468814072 @default.
• W2012176405 cites W4252910375 @default.
• W2012176405 doi "https://doi.org/10.2298/vsp0511803h" @default.
• W2012176405 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16375203" @default.
• W2012176405 hasPublicationYear "2005" @default.
• W2012176405 type Work @default.
• W2012176405 sameAs 2012176405 @default.
• W2012176405 citedByCount "1" @default.
• W2012176405 countsByYear W20121764052020 @default.
• W2012176405 crossrefType "journal-article" @default.
• W2012176405 hasAuthorship W2012176405A5041422883 @default.
• W2012176405 hasAuthorship W2012176405A5044854052 @default.
• W2012176405 hasAuthorship W2012176405A5062083658 @default.
• W2012176405 hasAuthorship W2012176405A5074614794 @default.
• W2012176405 hasBestOaLocation W20121764051 @default.
• W2012176405 hasConcept C126322002 @default.
• W2012176405 hasConcept C134018914 @default.
• W2012176405 hasConcept C142724271 @default.
• W2012176405 hasConcept C164705383 @default.
• W2012176405 hasConcept C204787440 @default.
• W2012176405 hasConcept C27081682 @default.
• W2012176405 hasConcept C2776452961 @default.
• W2012176405 hasConcept C2777391703 @default.
• W2012176405 hasConcept C2777953023 @default.
• W2012176405 hasConcept C2778163477 @default.
• W2012176405 hasConcept C2778270857 @default.
• W2012176405 hasConcept C2779306644 @default.
• W2012176405 hasConcept C2780221984 @default.
• W2012176405 hasConcept C2780780548 @default.
• W2012176405 hasConcept C511355011 @default.
• W2012176405 hasConcept C544821477 @default.
• W2012176405 hasConcept C71924100 @default.
• W2012176405 hasConcept C84393581 @default.
• W2012176405 hasConceptScore W2012176405C126322002 @default.
• W2012176405 hasConceptScore W2012176405C134018914 @default.
• W2012176405 hasConceptScore W2012176405C142724271 @default.
• W2012176405 hasConceptScore W2012176405C164705383 @default.
• W2012176405 hasConceptScore W2012176405C204787440 @default.
• W2012176405 hasConceptScore W2012176405C27081682 @default.
• W2012176405 hasConceptScore W2012176405C2776452961 @default.
• W2012176405 hasConceptScore W2012176405C2777391703 @default.
• W2012176405 hasConceptScore W2012176405C2777953023 @default.
• W2012176405 hasConceptScore W2012176405C2778163477 @default.
• W2012176405 hasConceptScore W2012176405C2778270857 @default.
• W2012176405 hasConceptScore W2012176405C2779306644 @default.
• W2012176405 hasConceptScore W2012176405C2780221984 @default.
• W2012176405 hasConceptScore W2012176405C2780780548 @default.
• W2012176405 hasConceptScore W2012176405C511355011 @default.
• W2012176405 hasConceptScore W2012176405C544821477 @default.
• W2012176405 hasConceptScore W2012176405C71924100 @default.

• next