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- W2012185417 abstract "Two cases of C cell hyperplasia and one case of C cell carcinoma of the thyroid glands were bilaterally recognized in 11 sheep with experimentally-induced lymphosarcoma. The serum calcium concentration in the C cell carcinoma case was slightly increased above the normal concentration of around 9 mg per dl. Bilateral C cell hyperplasia also developed in the thyroid lobes of the C cell carcinoma case. Immunohistochemically, hyperplastic C cells and tumour cells were positive for calcitonin, calcitonin gene-related peptide, chromogranin A and neurone-specific enolase. No amyloid deposition nor multiple endocrine neoplasia was demonstrated in any of the cases. Ultrastructurally, many secretory granules were observed in the cytoplasm of neoplastic cells constituting the C cell carcinoma and in the hyperplastic C cells." @default.
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- W2012185417 date "1991-10-01" @default.
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- W2012185417 title "C cell hyperplasia and carcinoma developing in sheep with experimentally-induced lymphosarcoma" @default.
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- W2012185417 doi "https://doi.org/10.1016/s0021-9975(08)80199-5" @default.
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