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- W2012190971 endingPage "111" @default.
- W2012190971 startingPage "103" @default.
- W2012190971 abstract "Over the past two decades, there has been intense interest in designing and implementing selective (bioorthogonal) reactions for biomolecule tracking. Here we review the most widely used bioorthogonal chemistries in live cells and animals, drawing particular attention to the unique functional groups underlying these transformations. We also describe recent efforts to tune functional group reactivities and stabilities to access even more rapid and selective chemistries. Last, we highlight ongoing challenges in identifying new bioorthogonal reagents and combinations of reactions that can be used concurrently to tag multiple biomolecules." @default.
- W2012190971 created "2016-06-24" @default.
- W2012190971 creator A5003663459 @default.
- W2012190971 creator A5022073676 @default.
- W2012190971 creator A5038454561 @default.
- W2012190971 date "2014-08-01" @default.
- W2012190971 modified "2023-09-27" @default.
- W2012190971 title "Building better bioorthogonal reactions" @default.
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- W2012190971 doi "https://doi.org/10.1016/j.cbpa.2014.07.002" @default.
- W2012190971 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25086220" @default.
- W2012190971 hasPublicationYear "2014" @default.
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