Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012196340> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2012196340 abstract "Neuronal networks produced in cell culture are a unique tool to provide information about synapses formation, development and functionality. Several geometrical, physical and chemical cues play a role in neuron adhesion and neurite outgrowth. We have used a nano-drop method to pattern agarose coated surfaces with an adhesion protein (PDL) and we have subsequently monitored the growth of neural networks. Depending on its thickness, the intermixed agarose/PDL layer was proved to be a successful substrate to confine the neural network and to guide its growth. In particular, for thickness of the polymer cushion below 100 nm, neurons formed connections and remained in morphologically healthy conditions up to 21 DIV. The correlation between surface properties (morphology, stiffness, roughness, charge) and neuron adhesion and survival was investigated by AFM. Force-Volume mapping of the surface showed a dominating effect of surface stiffness vs topography. In order to allow connectivity, a critical distance of 80 μm between spots of adhesion protein was found. Finally, the functionality at 21 DIV of 2D networks grown on agarose/PDL substrates patterned by micro contact printing was proved by patch clamp and by the measurements of the basal activity on micro electrode arrays." @default.
- W2012196340 created "2016-06-24" @default.
- W2012196340 creator A5053398823 @default.
- W2012196340 creator A5075245204 @default.
- W2012196340 creator A5087177497 @default.
- W2012196340 creator A5088983421 @default.
- W2012196340 date "2011-02-01" @default.
- W2012196340 modified "2023-09-27" @default.
- W2012196340 title "Characterization of the Neuron/Substrate Interface of Long Term 2d Neural Networks Obtained by Nano Drop Printing" @default.
- W2012196340 doi "https://doi.org/10.1016/j.bpj.2010.12.724" @default.
- W2012196340 hasPublicationYear "2011" @default.
- W2012196340 type Work @default.
- W2012196340 sameAs 2012196340 @default.
- W2012196340 citedByCount "0" @default.
- W2012196340 crossrefType "journal-article" @default.
- W2012196340 hasAuthorship W2012196340A5053398823 @default.
- W2012196340 hasAuthorship W2012196340A5075245204 @default.
- W2012196340 hasAuthorship W2012196340A5087177497 @default.
- W2012196340 hasAuthorship W2012196340A5088983421 @default.
- W2012196340 hasBestOaLocation W20121963401 @default.
- W2012196340 hasConcept C113246987 @default.
- W2012196340 hasConcept C12554922 @default.
- W2012196340 hasConcept C159985019 @default.
- W2012196340 hasConcept C169760540 @default.
- W2012196340 hasConcept C171250308 @default.
- W2012196340 hasConcept C185592680 @default.
- W2012196340 hasConcept C186060115 @default.
- W2012196340 hasConcept C18903297 @default.
- W2012196340 hasConcept C192562407 @default.
- W2012196340 hasConcept C202751555 @default.
- W2012196340 hasConcept C2777289219 @default.
- W2012196340 hasConcept C2778476535 @default.
- W2012196340 hasConcept C2778794669 @default.
- W2012196340 hasConcept C2781345722 @default.
- W2012196340 hasConcept C33373654 @default.
- W2012196340 hasConcept C41008148 @default.
- W2012196340 hasConcept C43617362 @default.
- W2012196340 hasConcept C55493867 @default.
- W2012196340 hasConcept C71039073 @default.
- W2012196340 hasConcept C76155785 @default.
- W2012196340 hasConcept C84416704 @default.
- W2012196340 hasConcept C86803240 @default.
- W2012196340 hasConceptScore W2012196340C113246987 @default.
- W2012196340 hasConceptScore W2012196340C12554922 @default.
- W2012196340 hasConceptScore W2012196340C159985019 @default.
- W2012196340 hasConceptScore W2012196340C169760540 @default.
- W2012196340 hasConceptScore W2012196340C171250308 @default.
- W2012196340 hasConceptScore W2012196340C185592680 @default.
- W2012196340 hasConceptScore W2012196340C186060115 @default.
- W2012196340 hasConceptScore W2012196340C18903297 @default.
- W2012196340 hasConceptScore W2012196340C192562407 @default.
- W2012196340 hasConceptScore W2012196340C202751555 @default.
- W2012196340 hasConceptScore W2012196340C2777289219 @default.
- W2012196340 hasConceptScore W2012196340C2778476535 @default.
- W2012196340 hasConceptScore W2012196340C2778794669 @default.
- W2012196340 hasConceptScore W2012196340C2781345722 @default.
- W2012196340 hasConceptScore W2012196340C33373654 @default.
- W2012196340 hasConceptScore W2012196340C41008148 @default.
- W2012196340 hasConceptScore W2012196340C43617362 @default.
- W2012196340 hasConceptScore W2012196340C55493867 @default.
- W2012196340 hasConceptScore W2012196340C71039073 @default.
- W2012196340 hasConceptScore W2012196340C76155785 @default.
- W2012196340 hasConceptScore W2012196340C84416704 @default.
- W2012196340 hasConceptScore W2012196340C86803240 @default.
- W2012196340 hasLocation W20121963401 @default.
- W2012196340 hasOpenAccess W2012196340 @default.
- W2012196340 hasPrimaryLocation W20121963401 @default.
- W2012196340 hasRelatedWork W1992976697 @default.
- W2012196340 hasRelatedWork W2006119914 @default.
- W2012196340 hasRelatedWork W2014443148 @default.
- W2012196340 hasRelatedWork W2030231709 @default.
- W2012196340 hasRelatedWork W2049878449 @default.
- W2012196340 hasRelatedWork W2052073698 @default.
- W2012196340 hasRelatedWork W2055506636 @default.
- W2012196340 hasRelatedWork W2056330129 @default.
- W2012196340 hasRelatedWork W2057183055 @default.
- W2012196340 hasRelatedWork W2081471470 @default.
- W2012196340 hasRelatedWork W2086037466 @default.
- W2012196340 hasRelatedWork W2104118028 @default.
- W2012196340 hasRelatedWork W2140746710 @default.
- W2012196340 hasRelatedWork W2150353081 @default.
- W2012196340 hasRelatedWork W2321544337 @default.
- W2012196340 hasRelatedWork W2767558445 @default.
- W2012196340 hasRelatedWork W2896328651 @default.
- W2012196340 hasRelatedWork W3183176349 @default.
- W2012196340 hasRelatedWork W855159590 @default.
- W2012196340 hasRelatedWork W2377616613 @default.
- W2012196340 isParatext "false" @default.
- W2012196340 isRetracted "false" @default.
- W2012196340 magId "2012196340" @default.
- W2012196340 workType "article" @default.