FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012198271> ?p ?o ?g. }

• W2012198271 endingPage "8" @default.
• W2012198271 startingPage "5" @default.
• W2012198271 abstract "The purpose of the present study was to observe the response and changes of cranial suture to the distraction forces in growing goats and to examine the expression patterns of TGF-β and BMP during suture distraction.Twenty growing goats were divided into three groups: control (n=4), experimental (n=12), and sham (n=4). A pure titanium distractor was placed in the coronal suture in both the sham and experimental groups. After healing, the distractor was activated for distraction of the coronal suture at a rate of 0.5 mm/day for 8 days in the experimental group. Three animals were killed respectively, at 0，2，4 and 8 weeks after completion of suture distraction. No force was applied in the sham group. X- Ray examination was taken and the coronal suture samples were harvested and processed for histological analysis and scanning electron microscopic analysis and immunohistochemistry of TGF-β and BMP. The coronal sutures of experimental group were separated successfully. Signs of intramembranous bone formation and remodeling were found in the distracted suture，and the sutural structure almost return to its normal state at 8 weeks after end of distraction. At 0 and 2 weeks after completion of suture distraction, the collagen fiber bundles were strengthened and aligned in the direction of the distracted forces. Strong expression of BMP and TGF-β were detected in the fibroblast-like cells and the active osteoblasts. At 4 weeks after suture distraction, signs of intramembranous ossification were found in the edge areas of the distracted suture, and the positive staining of BMP and TGF-β was still noted in the osteoblasts around the newly formed bone trabeculae. This study suggests that cranial suture expansion can be achieved in growing animal by distraction osteogenesis. Mechanical strain resulted from distractor can induce the adaptive remodeling in the cranial suture of growing goats. It also suggests BMP and TGF-β may play very important roles in the process of bone formation and remodeling during suture distraction osteogenesis." @default.
• W2012198271 created "2016-06-24" @default.
• W2012198271 creator A5011340451 @default.
• W2012198271 creator A5024181386 @default.
• W2012198271 creator A5029221829 @default.
• W2012198271 creator A5065365001 @default.
• W2012198271 creator A5068170712 @default.
• W2012198271 creator A5085950142 @default.
• W2012198271 date "2007-07-01" @default.
• W2012198271 modified "2023-09-25" @default.
• W2012198271 title "The Bone Remodeling and Cellular Responses to Cranial Suture Distraction Osteogenesis in Growing Goats" @default.
• W2012198271 doi "https://doi.org/10.4028/www.scientific.net/kem.342-343.5" @default.
• W2012198271 hasPublicationYear "2007" @default.
• W2012198271 type Work @default.
• W2012198271 sameAs 2012198271 @default.
• W2012198271 citedByCount "0" @default.
• W2012198271 crossrefType "journal-article" @default.
• W2012198271 hasAuthorship W2012198271A5011340451 @default.
• W2012198271 hasAuthorship W2012198271A5024181386 @default.
• W2012198271 hasAuthorship W2012198271A5029221829 @default.
• W2012198271 hasAuthorship W2012198271A5065365001 @default.
• W2012198271 hasAuthorship W2012198271A5068170712 @default.
• W2012198271 hasAuthorship W2012198271A5085950142 @default.
• W2012198271 hasConcept C105702510 @default.
• W2012198271 hasConcept C13483470 @default.
• W2012198271 hasConcept C169760540 @default.
• W2012198271 hasConcept C188945261 @default.
• W2012198271 hasConcept C2776378700 @default.
• W2012198271 hasConcept C2776819169 @default.
• W2012198271 hasConcept C2777327002 @default.
• W2012198271 hasConcept C2778842504 @default.
• W2012198271 hasConcept C71924100 @default.
• W2012198271 hasConcept C86803240 @default.
• W2012198271 hasConceptScore W2012198271C105702510 @default.
• W2012198271 hasConceptScore W2012198271C13483470 @default.
• W2012198271 hasConceptScore W2012198271C169760540 @default.
• W2012198271 hasConceptScore W2012198271C188945261 @default.
• W2012198271 hasConceptScore W2012198271C2776378700 @default.
• W2012198271 hasConceptScore W2012198271C2776819169 @default.
• W2012198271 hasConceptScore W2012198271C2777327002 @default.
• W2012198271 hasConceptScore W2012198271C2778842504 @default.
• W2012198271 hasConceptScore W2012198271C71924100 @default.
• W2012198271 hasConceptScore W2012198271C86803240 @default.
• W2012198271 hasLocation W20121982711 @default.
• W2012198271 hasOpenAccess W2012198271 @default.
• W2012198271 hasPrimaryLocation W20121982711 @default.
• W2012198271 hasRelatedWork W1495918494 @default.
• W2012198271 hasRelatedWork W2012198271 @default.
• W2012198271 hasRelatedWork W2027268411 @default.
• W2012198271 hasRelatedWork W2092865462 @default.
• W2012198271 hasRelatedWork W2222148051 @default.
• W2012198271 hasRelatedWork W2329504428 @default.
• W2012198271 hasRelatedWork W2335404538 @default.
• W2012198271 hasRelatedWork W2351041735 @default.
• W2012198271 hasRelatedWork W2370576940 @default.
• W2012198271 hasRelatedWork W2393473531 @default.
• W2012198271 hasVolume "342-343" @default.
• W2012198271 isParatext "false" @default.
• W2012198271 isRetracted "false" @default.
• W2012198271 magId "2012198271" @default.
• W2012198271 workType "article" @default.