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- W2012205249 abstract "Evaluation of: Chang HH, Lu MY, Liao YM et al. Improved efficacy and tolerability of oral deferasirox by twice-daily dosing for patients with transfusion-dependent β-thalassemia. Pediatr. Blood Cancer 56(3), 420–424 (2011).Chronic transfusional iron overload leads to significant morbidity and mortality in patients with β-thalassemia major. The once-daily oral iron chelator, deferasirox, opened new horizons for the management of transfusional siderosis. A large body of evidence is now available regarding its efficacy and safety. Nevertheless, some patients remain unresponsive or intolerant to the adverse events of the drug. Chang et al. evaluated the benefit of twice-daily dosing in this setting. The authors concluded that twice-daily deferasirox improves responsiveness and tolerability. Even though the study included only a small number of patients, it offers promising insights that should be interpreted with caution." @default.
- W2012205249 created "2016-06-24" @default.
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- W2012205249 date "2011-08-01" @default.
- W2012205249 modified "2023-09-26" @default.
- W2012205249 title "Managing unresponsiveness or intolerance to deferasirox therapy: a tale of two doses" @default.
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- W2012205249 doi "https://doi.org/10.1586/ehm.11.36" @default.
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