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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012207925> ?p ?o ?g. }

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• W2012207925 abstract "A non-specific cation channel in cultured human umbilical vein endothelial cells was obtained by cell-attached patch-clamp study. This channel showed a conductance of 28 pS when both pipette and bath contained 140 mM potassium chloride. when pipette solution was changed into 140 sodium chloride with 5 mM calcium chloride, the conductance was 26 pS. when 120 mM calcium chloride was used as the only cation in the pipette, a conductance of 6 pS was obtained. Bath application of cyclopiazonic acid, an inhibitor of the sarcoplasmic reticulum Ca2+ pump in smooth muscle and other tissues, dose dependently activates this non-specific cation channel. It is assumed that cyclopiazonic acid by blockade of the refilling of Ca2+ stores depletes the rapidly exchanging intracellular Ca2+ stores and this action stimulates Ca2+ influx through the non-specific cation channels in human umbilical vein endothelial cells." @default.
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• W2012207925 date "1994-01-01" @default.
• W2012207925 modified "2023-10-17" @default.
• W2012207925 title "Cyclopiazonic acid stimulates Ca2+ influx through non-specific cation channels in endothelial cells" @default.
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• W2012207925 doi "https://doi.org/10.1016/0014-2999(94)90391-3" @default.
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