Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012248483> ?p ?o ?g. }
- W2012248483 endingPage "2255" @default.
- W2012248483 startingPage "2248" @default.
- W2012248483 abstract "Ghrelin is a stomach hormone, secreted into the bloodstream, that initiates food intake by activating NPY/AgRP neurons in the hypothalamic acruate nucleus. This review focuses on recent evidence that details the mechanisms through which ghrelin activate receptors on NPY neurons and downstream signaling within NPY neurons. The downstream signaling involves a novel CaMKK-AMPK-CPT1-UCP2 pathway that enhances mitochondrial efficiency and buffers reactive oxygen species in order to maintain an appropriate firing response in NPY. Recent evidence that shows metabolic status affects ghrelin signaling in NPY is also described. In particular, ghrelin does not activate NPY neurons in diet-induced obese mice and ghrelin does not increase food intake. The potential mechanisms and implications of ghrelin resistance are discussed." @default.
- W2012248483 created "2016-06-24" @default.
- W2012248483 creator A5007604702 @default.
- W2012248483 date "2011-11-01" @default.
- W2012248483 modified "2023-09-27" @default.
- W2012248483 title "Central mechanisms involved in the orexigenic actions of ghrelin" @default.
- W2012248483 cites W1562357843 @default.
- W2012248483 cites W1596010380 @default.
- W2012248483 cites W1616806865 @default.
- W2012248483 cites W1965200419 @default.
- W2012248483 cites W1970637709 @default.
- W2012248483 cites W1971692114 @default.
- W2012248483 cites W1974558371 @default.
- W2012248483 cites W1975010632 @default.
- W2012248483 cites W1981415589 @default.
- W2012248483 cites W1987555746 @default.
- W2012248483 cites W1988803699 @default.
- W2012248483 cites W1990095603 @default.
- W2012248483 cites W1991742828 @default.
- W2012248483 cites W1994554353 @default.
- W2012248483 cites W1995163572 @default.
- W2012248483 cites W2008646871 @default.
- W2012248483 cites W2015037392 @default.
- W2012248483 cites W2016850962 @default.
- W2012248483 cites W2018127398 @default.
- W2012248483 cites W2020843850 @default.
- W2012248483 cites W2027397115 @default.
- W2012248483 cites W2032668395 @default.
- W2012248483 cites W2038944901 @default.
- W2012248483 cites W2039033342 @default.
- W2012248483 cites W2040509326 @default.
- W2012248483 cites W2046406271 @default.
- W2012248483 cites W2061725130 @default.
- W2012248483 cites W2064842282 @default.
- W2012248483 cites W2070382843 @default.
- W2012248483 cites W2074303577 @default.
- W2012248483 cites W2082629592 @default.
- W2012248483 cites W2083560906 @default.
- W2012248483 cites W2085372550 @default.
- W2012248483 cites W2086139024 @default.
- W2012248483 cites W2086593059 @default.
- W2012248483 cites W2086950122 @default.
- W2012248483 cites W2087867196 @default.
- W2012248483 cites W2088777766 @default.
- W2012248483 cites W2090905402 @default.
- W2012248483 cites W2095454212 @default.
- W2012248483 cites W2095461204 @default.
- W2012248483 cites W2096591765 @default.
- W2012248483 cites W2099542131 @default.
- W2012248483 cites W2101870887 @default.
- W2012248483 cites W2106488251 @default.
- W2012248483 cites W2107620313 @default.
- W2012248483 cites W2113877948 @default.
- W2012248483 cites W2114922768 @default.
- W2012248483 cites W2115254413 @default.
- W2012248483 cites W2115651249 @default.
- W2012248483 cites W2120228339 @default.
- W2012248483 cites W2125312207 @default.
- W2012248483 cites W2129528230 @default.
- W2012248483 cites W2131380293 @default.
- W2012248483 cites W2140550416 @default.
- W2012248483 cites W2141762813 @default.
- W2012248483 cites W2142924698 @default.
- W2012248483 cites W2143711558 @default.
- W2012248483 cites W2144489715 @default.
- W2012248483 cites W2144925128 @default.
- W2012248483 cites W2148187505 @default.
- W2012248483 cites W2149686779 @default.
- W2012248483 cites W2150551377 @default.
- W2012248483 cites W2152682803 @default.
- W2012248483 cites W2158711945 @default.
- W2012248483 cites W2159536456 @default.
- W2012248483 cites W2162198402 @default.
- W2012248483 cites W2163066715 @default.
- W2012248483 cites W2168988227 @default.
- W2012248483 cites W4232589109 @default.
- W2012248483 cites W4242272012 @default.
- W2012248483 doi "https://doi.org/10.1016/j.peptides.2011.05.014" @default.
- W2012248483 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21619904" @default.
- W2012248483 hasPublicationYear "2011" @default.
- W2012248483 type Work @default.
- W2012248483 sameAs 2012248483 @default.
- W2012248483 citedByCount "125" @default.
- W2012248483 countsByYear W20122484832012 @default.
- W2012248483 countsByYear W20122484832013 @default.
- W2012248483 countsByYear W20122484832014 @default.
- W2012248483 countsByYear W20122484832015 @default.
- W2012248483 countsByYear W20122484832016 @default.
- W2012248483 countsByYear W20122484832017 @default.
- W2012248483 countsByYear W20122484832018 @default.
- W2012248483 countsByYear W20122484832019 @default.
- W2012248483 countsByYear W20122484832020 @default.
- W2012248483 countsByYear W20122484832021 @default.
- W2012248483 countsByYear W20122484832022 @default.
- W2012248483 countsByYear W20122484832023 @default.
- W2012248483 crossrefType "journal-article" @default.
- W2012248483 hasAuthorship W2012248483A5007604702 @default.
- W2012248483 hasConcept C118303440 @default.