Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012251390> ?p ?o ?g. }
- W2012251390 endingPage "14530" @default.
- W2012251390 startingPage "14505" @default.
- W2012251390 abstract "Invasive aspergillosis is a life-threatening lung or systemic infection caused by the opportunistic mold Aspergillus fumigatus. The disease affects mainly immunocompromised hosts, and patients with hematological malignances or who have been submitted to stem cell transplantation are at high risk. Despite the current use of Platelia™ Aspergillus as a diagnostic test, the early diagnosis of invasive aspergillosis remains a major challenge in improving the prognosis of the disease. In this study, we used an immunoproteomic approach to identify proteins that could be putative candidates for the early diagnosis of invasive aspergillosis. Antigenic proteins expressed in the first steps of A. fumigatus germination occurring in a human host were revealed using 2-D Western immunoblots with the serum of patients who had previously been classified as probable and proven for invasive aspergillosis. Forty antigenic proteins were identified using mass spectrometry (MS/MS). A BLAST analysis revealed that two of these proteins showed low homology with proteins of either the human host or etiological agents of other invasive fungal infections. To our knowledge, this is the first report describing specific antigenic proteins of A. fumigatus germlings that are recognized by sera of patients with confirmed invasive aspergillosis who were from two separate hospital units." @default.
- W2012251390 created "2016-06-24" @default.
- W2012251390 creator A5016144976 @default.
- W2012251390 creator A5031722408 @default.
- W2012251390 creator A5040371103 @default.
- W2012251390 creator A5053657226 @default.
- W2012251390 creator A5062740243 @default.
- W2012251390 creator A5082676408 @default.
- W2012251390 creator A5088012565 @default.
- W2012251390 date "2014-08-20" @default.
- W2012251390 modified "2023-09-27" @default.
- W2012251390 title "Immunoproteome of Aspergillus fumigatus Using Sera of Patients with Invasive Aspergillosis" @default.
- W2012251390 cites W1532616066 @default.
- W2012251390 cites W1546472944 @default.
- W2012251390 cites W1760120130 @default.
- W2012251390 cites W1952604877 @default.
- W2012251390 cites W1963804365 @default.
- W2012251390 cites W1974806769 @default.
- W2012251390 cites W1977944550 @default.
- W2012251390 cites W1985301666 @default.
- W2012251390 cites W1997330385 @default.
- W2012251390 cites W1998551407 @default.
- W2012251390 cites W2005520698 @default.
- W2012251390 cites W2006061378 @default.
- W2012251390 cites W2009668088 @default.
- W2012251390 cites W2016936846 @default.
- W2012251390 cites W2022224941 @default.
- W2012251390 cites W2025725036 @default.
- W2012251390 cites W2030852198 @default.
- W2012251390 cites W2033687641 @default.
- W2012251390 cites W2036068456 @default.
- W2012251390 cites W2040132160 @default.
- W2012251390 cites W2047552654 @default.
- W2012251390 cites W2048312779 @default.
- W2012251390 cites W2057229295 @default.
- W2012251390 cites W2063651550 @default.
- W2012251390 cites W2066793150 @default.
- W2012251390 cites W2068169646 @default.
- W2012251390 cites W2068768342 @default.
- W2012251390 cites W2084700329 @default.
- W2012251390 cites W2090677789 @default.
- W2012251390 cites W2095079034 @default.
- W2012251390 cites W2102160298 @default.
- W2012251390 cites W2104213638 @default.
- W2012251390 cites W2107580083 @default.
- W2012251390 cites W2114164442 @default.
- W2012251390 cites W2124088686 @default.
- W2012251390 cites W2131147322 @default.
- W2012251390 cites W2133328722 @default.
- W2012251390 cites W2135315031 @default.
- W2012251390 cites W2136735616 @default.
- W2012251390 cites W2137371843 @default.
- W2012251390 cites W2148896980 @default.
- W2012251390 cites W2153911335 @default.
- W2012251390 cites W2154375528 @default.
- W2012251390 cites W2156492770 @default.
- W2012251390 cites W2156924221 @default.
- W2012251390 cites W2158059832 @default.
- W2012251390 cites W2159606583 @default.
- W2012251390 cites W2160224853 @default.
- W2012251390 cites W2166107031 @default.
- W2012251390 cites W2166734004 @default.
- W2012251390 cites W2167177000 @default.
- W2012251390 cites W2171992477 @default.
- W2012251390 cites W2324262342 @default.
- W2012251390 cites W2338771957 @default.
- W2012251390 cites W4230924492 @default.
- W2012251390 doi "https://doi.org/10.3390/ijms150814505" @default.
- W2012251390 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4159865" @default.
- W2012251390 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25141105" @default.
- W2012251390 hasPublicationYear "2014" @default.
- W2012251390 type Work @default.
- W2012251390 sameAs 2012251390 @default.
- W2012251390 citedByCount "21" @default.
- W2012251390 countsByYear W20122513902015 @default.
- W2012251390 countsByYear W20122513902016 @default.
- W2012251390 countsByYear W20122513902017 @default.
- W2012251390 countsByYear W20122513902018 @default.
- W2012251390 countsByYear W20122513902019 @default.
- W2012251390 countsByYear W20122513902020 @default.
- W2012251390 countsByYear W20122513902021 @default.
- W2012251390 countsByYear W20122513902022 @default.
- W2012251390 countsByYear W20122513902023 @default.
- W2012251390 crossrefType "journal-article" @default.
- W2012251390 hasAuthorship W2012251390A5016144976 @default.
- W2012251390 hasAuthorship W2012251390A5031722408 @default.
- W2012251390 hasAuthorship W2012251390A5040371103 @default.
- W2012251390 hasAuthorship W2012251390A5053657226 @default.
- W2012251390 hasAuthorship W2012251390A5062740243 @default.
- W2012251390 hasAuthorship W2012251390A5082676408 @default.
- W2012251390 hasAuthorship W2012251390A5088012565 @default.
- W2012251390 hasBestOaLocation W20122513901 @default.
- W2012251390 hasConcept C126322002 @default.
- W2012251390 hasConcept C141105273 @default.
- W2012251390 hasConcept C147483822 @default.
- W2012251390 hasConcept C159654299 @default.
- W2012251390 hasConcept C203014093 @default.
- W2012251390 hasConcept C2776391196 @default.