FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012253186> ?p ?o ?g. }

• W2012253186 endingPage "26" @default.
• W2012253186 startingPage "2" @default.
• W2012253186 abstract "Estrogens exert a wide variety of actions on reproductive and non-reproductive functions. These effects are mediated by slow and long lasting genomic as well as rapid and transient non-genomic mechanisms. Besides the host of studies demonstrating the role of genomic actions at the physiological and behavioral level, mounting evidence highlights the functional significance of non-genomic effects. However, the source of the rapid changes in estrogen availability that are necessary to sustain their fast actions is rarely questioned. For example, the rise of plasma estrogens at pro-estrus that represents one of the fastest documented changes in plasma estrogen concentration appears too slow to explain these actions. Alternatively, estrogen can be synthesized in the brain by the enzyme aromatase providing a source of locally high concentrations of the steroid. Furthermore, recent studies demonstrate that brain aromatase can be rapidly modulated by afferent inputs, including glutamatergic afferents. A role for rapid changes in estrogen production in the central nervous system is supported by experiments showing that acute aromatase inhibition affects nociception as well as male sexual behavior and that preoptic aromatase activity is rapidly (within min) modulated following mating. Such mechanisms thus fulfill the gap existing between the fast actions of estrogen and their mode of production and open new avenues for the understanding of estrogenic effects on the brain." @default.
• W2012253186 created "2016-06-24" @default.
• W2012253186 creator A5021972695 @default.
• W2012253186 creator A5039368497 @default.
• W2012253186 creator A5082634759 @default.
• W2012253186 date "2006-12-01" @default.
• W2012253186 modified "2023-10-14" @default.
• W2012253186 title "Functional significance of the rapid regulation of brain estrogen action: Where do the estrogens come from?" @default.
• W2012253186 cites W1503161932 @default.
• W2012253186 cites W1504988281 @default.
• W2012253186 cites W1508873464 @default.
• W2012253186 cites W1509103176 @default.
• W2012253186 cites W1509817160 @default.
• W2012253186 cites W1516762603 @default.
• W2012253186 cites W1535354952 @default.
• W2012253186 cites W1601675094 @default.
• W2012253186 cites W1621380982 @default.
• W2012253186 cites W1661647511 @default.
• W2012253186 cites W1749538909 @default.
• W2012253186 cites W1782420323 @default.
• W2012253186 cites W1795513906 @default.
• W2012253186 cites W1879188060 @default.
• W2012253186 cites W1881159824 @default.
• W2012253186 cites W192986845 @default.
• W2012253186 cites W19388397 @default.
• W2012253186 cites W1954468845 @default.
• W2012253186 cites W1963554387 @default.
• W2012253186 cites W1963831656 @default.
• W2012253186 cites W1963954790 @default.
• W2012253186 cites W1964726163 @default.
• W2012253186 cites W1965174806 @default.
• W2012253186 cites W1965383569 @default.
• W2012253186 cites W1965752446 @default.
• W2012253186 cites W1966256836 @default.
• W2012253186 cites W1967213586 @default.
• W2012253186 cites W1967373546 @default.
• W2012253186 cites W1967501806 @default.
• W2012253186 cites W1967933091 @default.
• W2012253186 cites W1968706251 @default.
• W2012253186 cites W1968982259 @default.
• W2012253186 cites W1969291285 @default.
• W2012253186 cites W1969424793 @default.
• W2012253186 cites W1969474756 @default.
• W2012253186 cites W1970122155 @default.
• W2012253186 cites W1970211188 @default.
• W2012253186 cites W1970576862 @default.
• W2012253186 cites W1972345891 @default.
• W2012253186 cites W1972414087 @default.
• W2012253186 cites W1972520826 @default.
• W2012253186 cites W1972747545 @default.
• W2012253186 cites W1973613641 @default.
• W2012253186 cites W1974109772 @default.
• W2012253186 cites W1974114533 @default.
• W2012253186 cites W1974267268 @default.
• W2012253186 cites W1974337154 @default.
• W2012253186 cites W1975566786 @default.
• W2012253186 cites W1975759742 @default.
• W2012253186 cites W1976862945 @default.
• W2012253186 cites W1977363491 @default.
• W2012253186 cites W1979540625 @default.
• W2012253186 cites W1979600059 @default.
• W2012253186 cites W1980437934 @default.
• W2012253186 cites W1981467972 @default.
• W2012253186 cites W1981475053 @default.
• W2012253186 cites W1983078327 @default.
• W2012253186 cites W1984113288 @default.
• W2012253186 cites W1984858425 @default.
• W2012253186 cites W1985405058 @default.
• W2012253186 cites W1985471892 @default.
• W2012253186 cites W1985622185 @default.
• W2012253186 cites W1985691553 @default.
• W2012253186 cites W1986115340 @default.
• W2012253186 cites W1986945081 @default.
• W2012253186 cites W1988240151 @default.
• W2012253186 cites W1988369035 @default.
• W2012253186 cites W1988959583 @default.
• W2012253186 cites W1989315787 @default.
• W2012253186 cites W1990873444 @default.
• W2012253186 cites W1992481216 @default.
• W2012253186 cites W1994879786 @default.
• W2012253186 cites W1996197907 @default.
• W2012253186 cites W1997131054 @default.
• W2012253186 cites W1997361225 @default.
• W2012253186 cites W1997891222 @default.
• W2012253186 cites W1998775418 @default.
• W2012253186 cites W2000531250 @default.
• W2012253186 cites W2000592915 @default.
• W2012253186 cites W2000977646 @default.
• W2012253186 cites W2001160131 @default.
• W2012253186 cites W2001402122 @default.
• W2012253186 cites W2002618947 @default.
• W2012253186 cites W2002789477 @default.
• W2012253186 cites W2004794537 @default.
• W2012253186 cites W2004885757 @default.
• W2012253186 cites W2005766913 @default.
• W2012253186 cites W2006035737 @default.
• W2012253186 cites W2006180961 @default.
• W2012253186 cites W2007718539 @default.

• next