FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012253492> ?p ?o ?g. }

• W2012253492 endingPage "348" @default.
• W2012253492 startingPage "344" @default.
• W2012253492 abstract "A competent aortic valve is essential to providing effective left ventricular assist device support. We have adopted a practice of central aortic valve closure by placing a simple coaptation stitch at left ventricular assist device implantation in patients with significant aortic insufficiency. We conducted a follow-up study to evaluate the efficacy and durability of this procedure.The study included patients who had undergone continuous flow left ventricular assist device implantation. The patients were divided into 2 groups, those who did not require any aortic procedure because the valve was competent and those who underwent central aortic valve closure for mild or greater aortic regurgitation. The clinical endpoints were mortality, progression or recurrence of aortic insufficiency, and reoperation for aortic valve pathologic features. Aortic insufficiency was measured qualitatively from mild to severe on a scale of 0 to 5.A total of 123 patients received continuous flow left ventricular assist devices from February 2007 to August 2011. Of those, 18 (15%) underwent central aortic valve closure at left ventricular assist device implantation because of significant aortic insufficiency (1.8 ± 1.4) and 105 who did not (competent aortic valve, 0.15 ± 0.43; P < .01). At follow-up (median, 312 days; range, 0-1429 days), the mean aortic insufficiency score remained low for the patients with central aortic valve closure (0.27 ± 0.46) in contrast to those without central aortic valve closure who experienced aortic insufficiency progression (0.78 ± 0.89; P = .02). In addition, the proportion of patients with more than mild aortic insufficiency was significantly less in the central aortic valve closure group (0% vs 18%; P = .05). The patients in the central aortic valve closure group were significantly older and had a greater incidence of renal failure at baseline. The 30-day mortality was greater in the central aortic valve closure group, but the late survival was similar between the 2 groups. No reoperations were required for recurrent aortic insufficiency.The results of our study have shown that repair of aortic insufficiency with a simple central coaptation stitch is effective and durable in left ventricular assist device-supported patients, with follow-up extending into 2 years. Although aortic insufficiency progressed over time in those with minimal native valve regurgitation initially, no such progression was noted in those with central aortic valve closure. Additional investigation is needed to evaluate whether prophylactic central aortic valve closure should be performed at left ventricular assist device implantation to avoid problematic aortic regurgitation developing over time, in particular in patients undergoing left ventricular assist device implantation for life-long (destination therapy) support." @default.
• W2012253492 created "2016-06-24" @default.
• W2012253492 creator A5003756186 @default.
• W2012253492 creator A5010251316 @default.
• W2012253492 creator A5018965634 @default.
• W2012253492 creator A5027915803 @default.
• W2012253492 creator A5058114715 @default.
• W2012253492 creator A5060236170 @default.
• W2012253492 creator A5070427868 @default.
• W2012253492 date "2014-01-01" @default.
• W2012253492 modified "2023-10-14" @default.
• W2012253492 title "Durability of central aortic valve closure in patients with continuous flow left ventricular assist devices" @default.
• W2012253492 cites W2007699952 @default.
• W2012253492 cites W2012016968 @default.
• W2012253492 cites W2021896146 @default.
• W2012253492 cites W2023900500 @default.
• W2012253492 cites W2031044247 @default.
• W2012253492 cites W2031081756 @default.
• W2012253492 cites W2036716682 @default.
• W2012253492 cites W2039468795 @default.
• W2012253492 cites W2067523509 @default.
• W2012253492 cites W2084714144 @default.
• W2012253492 cites W2121842052 @default.
• W2012253492 cites W2128637839 @default.
• W2012253492 cites W2143243226 @default.
• W2012253492 cites W2156993691 @default.
• W2012253492 cites W4298852576 @default.
• W2012253492 doi "https://doi.org/10.1016/j.jtcvs.2012.09.098" @default.
• W2012253492 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23246052" @default.
• W2012253492 hasPublicationYear "2014" @default.
• W2012253492 type Work @default.
• W2012253492 sameAs 2012253492 @default.
• W2012253492 citedByCount "60" @default.
• W2012253492 countsByYear W20122534922014 @default.
• W2012253492 countsByYear W20122534922015 @default.
• W2012253492 countsByYear W20122534922016 @default.
• W2012253492 countsByYear W20122534922017 @default.
• W2012253492 countsByYear W20122534922018 @default.
• W2012253492 countsByYear W20122534922019 @default.
• W2012253492 countsByYear W20122534922020 @default.
• W2012253492 countsByYear W20122534922021 @default.
• W2012253492 countsByYear W20122534922022 @default.
• W2012253492 countsByYear W20122534922023 @default.
• W2012253492 crossrefType "journal-article" @default.
• W2012253492 hasAuthorship W2012253492A5003756186 @default.
• W2012253492 hasAuthorship W2012253492A5010251316 @default.
• W2012253492 hasAuthorship W2012253492A5018965634 @default.
• W2012253492 hasAuthorship W2012253492A5027915803 @default.
• W2012253492 hasAuthorship W2012253492A5058114715 @default.
• W2012253492 hasAuthorship W2012253492A5060236170 @default.
• W2012253492 hasAuthorship W2012253492A5070427868 @default.
• W2012253492 hasBestOaLocation W20122534921 @default.
• W2012253492 hasConcept C126322002 @default.
• W2012253492 hasConcept C141071460 @default.
• W2012253492 hasConcept C164705383 @default.
• W2012253492 hasConcept C2776570981 @default.
• W2012253492 hasConcept C2778198053 @default.
• W2012253492 hasConcept C2778774980 @default.
• W2012253492 hasConcept C2779011268 @default.
• W2012253492 hasConcept C2779745306 @default.
• W2012253492 hasConcept C2779980429 @default.
• W2012253492 hasConcept C2780007028 @default.
• W2012253492 hasConcept C2780168065 @default.
• W2012253492 hasConcept C2780714102 @default.
• W2012253492 hasConcept C2993369777 @default.
• W2012253492 hasConcept C71924100 @default.
• W2012253492 hasConceptScore W2012253492C126322002 @default.
• W2012253492 hasConceptScore W2012253492C141071460 @default.
• W2012253492 hasConceptScore W2012253492C164705383 @default.
• W2012253492 hasConceptScore W2012253492C2776570981 @default.
• W2012253492 hasConceptScore W2012253492C2778198053 @default.
• W2012253492 hasConceptScore W2012253492C2778774980 @default.
• W2012253492 hasConceptScore W2012253492C2779011268 @default.
• W2012253492 hasConceptScore W2012253492C2779745306 @default.
• W2012253492 hasConceptScore W2012253492C2779980429 @default.
• W2012253492 hasConceptScore W2012253492C2780007028 @default.
• W2012253492 hasConceptScore W2012253492C2780168065 @default.
• W2012253492 hasConceptScore W2012253492C2780714102 @default.
• W2012253492 hasConceptScore W2012253492C2993369777 @default.
• W2012253492 hasConceptScore W2012253492C71924100 @default.
• W2012253492 hasIssue "1" @default.
• W2012253492 hasLocation W20122534921 @default.
• W2012253492 hasLocation W20122534922 @default.
• W2012253492 hasOpenAccess W2012253492 @default.
• W2012253492 hasPrimaryLocation W20122534921 @default.
• W2012253492 hasRelatedWork W1973004257 @default.
• W2012253492 hasRelatedWork W2042591338 @default.
• W2012253492 hasRelatedWork W2059480400 @default.
• W2012253492 hasRelatedWork W2170216762 @default.
• W2012253492 hasRelatedWork W236610154 @default.
• W2012253492 hasRelatedWork W2406247020 @default.
• W2012253492 hasRelatedWork W2414776017 @default.
• W2012253492 hasRelatedWork W2665025142 @default.
• W2012253492 hasRelatedWork W3032547875 @default.
• W2012253492 hasRelatedWork W3046716066 @default.
• W2012253492 hasVolume "147" @default.
• W2012253492 isParatext "false" @default.
• W2012253492 isRetracted "false" @default.

• next