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• W2012255493 abstract "Autophagy is a complex cellular process having multiple roles, depending on tissue, physiological, or pathological conditions. Major post-translational regulators of autophagy are well known, however, they have not yet been collected comprehensively. The precise and context-dependent regulation of autophagy necessitates additional regulators, including transcriptional and post-transcriptional components that are listed in various datasets. Prompted by the lack of systems-level autophagy-related information, we manually collected the literature and integrated external resources to gain a high coverage autophagy database. We developed an online resource, Autophagy Regulatory Network (ARN; http://autophagy-regulation.org), to provide an integrated and systems-level database for autophagy research. ARN contains manually curated, imported, and predicted interactions of autophagy components (1,485 proteins with 4,013 interactions) in humans. We listed 413 transcription factors and 386 miRNAs that could regulate autophagy components or their protein regulators. We also connected the above-mentioned autophagy components and regulators with signaling pathways from the SignaLink 2 resource. The user-friendly website of ARN allows researchers without computational background to search, browse, and download the database. The database can be downloaded in SQL, CSV, BioPAX, SBML, PSI-MI, and in a Cytoscape CYS file formats. ARN has the potential to facilitate the experimental validation of novel autophagy components and regulators. In addition, ARN helps the investigation of transcription factors, miRNAs and signaling pathways implicated in the control of the autophagic pathway. The list of such known and predicted regulators could be important in pharmacological attempts against cancer and neurodegenerative diseases." @default.
• W2012255493 created "2016-06-24" @default.
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• W2012255493 date "2015-01-02" @default.
• W2012255493 modified "2023-10-10" @default.
• W2012255493 title "Autophagy Regulatory Network — A systems-level bioinformatics resource for studying the mechanism and regulation of autophagy" @default.
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• W2012255493 cites W1986512768 @default.
• W2012255493 cites W1988294855 @default.
• W2012255493 cites W1989773675 @default.
• W2012255493 cites W1995082021 @default.
• W2012255493 cites W1995582723 @default.
• W2012255493 cites W1999211990 @default.
• W2012255493 cites W2001554877 @default.
• W2012255493 cites W2001623365 @default.
• W2012255493 cites W2002197988 @default.
• W2012255493 cites W2003516452 @default.
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• W2012255493 cites W2023568310 @default.
• W2012255493 cites W2025452874 @default.
• W2012255493 cites W2026690931 @default.
• W2012255493 cites W2032601500 @default.
• W2012255493 cites W2036133589 @default.
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• W2012255493 cites W2042392223 @default.
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• W2012255493 cites W2043764521 @default.
• W2012255493 cites W2044514479 @default.
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• W2012255493 cites W2048270152 @default.
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• W2012255493 cites W2052685738 @default.
• W2012255493 cites W2056941102 @default.
• W2012255493 cites W2060603297 @default.
• W2012255493 cites W2065031087 @default.
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• W2012255493 cites W2089230333 @default.
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• W2012255493 doi "https://doi.org/10.4161/15548627.2014.994346" @default.
• W2012255493 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4502651" @default.
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