Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012259101> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2012259101 endingPage "920" @default.
- W2012259101 startingPage "912" @default.
- W2012259101 abstract "Quantitative MRI assessment of leukoencephalopathy is difficult because the MRI properties of leukoencephalopathy significantly overlap those of normal tissue. This report describes the use of an automated procedure for longitudinal measurement of tissue volume and relaxation times to quantify leukoencephalopathy. Images derived by using this procedure in patients undergoing therapy for acute lymphoblastic leukemia (ALL) are presented. Five examinations from each of five volunteers (25 examinations) were used to test the reproducibility of quantitated baseline and subsequent, normal-appearing images; the coefficients of variation were less than 2% for gray and white matter. Regions of leukoencephalopathy in patients were assessed by comparison with manual segmentation. Two radiologists manually segmented images from 15 randomly chosen MRI examinations that exhibited leukoencephalopathy. Kappa analyses showed that the two radiologists' interpretations were concordant (kappa = 0.70) and that each radiologist's interpretations agreed with the results of the automated procedure (kappa = 0.57 and 0.55). The clinical application of this method was illustrated by analysis of images from sequential MR examinations of two patients who developed leukoencephalopathy during treatment for ALL. The ultimate goal is to use these quantitative MR imaging measures to better understand therapy-induced neurotoxicity, which can be limited or even reversed with some combination of therapy adjustments and pharmacological and neurobehavioral interventions." @default.
- W2012259101 created "2016-06-24" @default.
- W2012259101 creator A5011167469 @default.
- W2012259101 creator A5077442433 @default.
- W2012259101 creator A5080224930 @default.
- W2012259101 creator A5090663988 @default.
- W2012259101 date "2002-04-22" @default.
- W2012259101 modified "2023-10-10" @default.
- W2012259101 title "Quantitative MRI assessment of leukoencephalopathy" @default.
- W2012259101 cites W1862200066 @default.
- W2012259101 cites W1973609741 @default.
- W2012259101 cites W1988090699 @default.
- W2012259101 cites W1990843888 @default.
- W2012259101 cites W1990980438 @default.
- W2012259101 cites W1991812856 @default.
- W2012259101 cites W2007656148 @default.
- W2012259101 cites W2037122726 @default.
- W2012259101 cites W2039255804 @default.
- W2012259101 cites W2058012809 @default.
- W2012259101 cites W2060446187 @default.
- W2012259101 cites W2069217819 @default.
- W2012259101 cites W2083414912 @default.
- W2012259101 cites W2116444896 @default.
- W2012259101 cites W2129280592 @default.
- W2012259101 cites W2132513126 @default.
- W2012259101 cites W2152146967 @default.
- W2012259101 cites W2158595748 @default.
- W2012259101 cites W2170750629 @default.
- W2012259101 cites W2171292608 @default.
- W2012259101 cites W2226649616 @default.
- W2012259101 cites W2319249430 @default.
- W2012259101 cites W2615412239 @default.
- W2012259101 doi "https://doi.org/10.1002/mrm.10124" @default.
- W2012259101 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2396564" @default.
- W2012259101 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11979570" @default.
- W2012259101 hasPublicationYear "2002" @default.
- W2012259101 type Work @default.
- W2012259101 sameAs 2012259101 @default.
- W2012259101 citedByCount "27" @default.
- W2012259101 countsByYear W20122591012013 @default.
- W2012259101 countsByYear W20122591012014 @default.
- W2012259101 countsByYear W20122591012021 @default.
- W2012259101 crossrefType "journal-article" @default.
- W2012259101 hasAuthorship W2012259101A5011167469 @default.
- W2012259101 hasAuthorship W2012259101A5077442433 @default.
- W2012259101 hasAuthorship W2012259101A5080224930 @default.
- W2012259101 hasAuthorship W2012259101A5090663988 @default.
- W2012259101 hasBestOaLocation W20122591011 @default.
- W2012259101 hasConcept C118552586 @default.
- W2012259101 hasConcept C126838900 @default.
- W2012259101 hasConcept C138885662 @default.
- W2012259101 hasConcept C143409427 @default.
- W2012259101 hasConcept C2778583010 @default.
- W2012259101 hasConcept C2778724333 @default.
- W2012259101 hasConcept C2780640218 @default.
- W2012259101 hasConcept C2780644213 @default.
- W2012259101 hasConcept C2781192897 @default.
- W2012259101 hasConcept C2989005 @default.
- W2012259101 hasConcept C41895202 @default.
- W2012259101 hasConcept C71924100 @default.
- W2012259101 hasConceptScore W2012259101C118552586 @default.
- W2012259101 hasConceptScore W2012259101C126838900 @default.
- W2012259101 hasConceptScore W2012259101C138885662 @default.
- W2012259101 hasConceptScore W2012259101C143409427 @default.
- W2012259101 hasConceptScore W2012259101C2778583010 @default.
- W2012259101 hasConceptScore W2012259101C2778724333 @default.
- W2012259101 hasConceptScore W2012259101C2780640218 @default.
- W2012259101 hasConceptScore W2012259101C2780644213 @default.
- W2012259101 hasConceptScore W2012259101C2781192897 @default.
- W2012259101 hasConceptScore W2012259101C2989005 @default.
- W2012259101 hasConceptScore W2012259101C41895202 @default.
- W2012259101 hasConceptScore W2012259101C71924100 @default.
- W2012259101 hasIssue "5" @default.
- W2012259101 hasLocation W20122591011 @default.
- W2012259101 hasLocation W20122591012 @default.
- W2012259101 hasLocation W20122591013 @default.
- W2012259101 hasLocation W20122591014 @default.
- W2012259101 hasOpenAccess W2012259101 @default.
- W2012259101 hasPrimaryLocation W20122591011 @default.
- W2012259101 hasRelatedWork W2000379621 @default.
- W2012259101 hasRelatedWork W2041842946 @default.
- W2012259101 hasRelatedWork W2044022462 @default.
- W2012259101 hasRelatedWork W2050459059 @default.
- W2012259101 hasRelatedWork W2088205067 @default.
- W2012259101 hasRelatedWork W2089587806 @default.
- W2012259101 hasRelatedWork W2337513960 @default.
- W2012259101 hasRelatedWork W2412622304 @default.
- W2012259101 hasRelatedWork W2799645914 @default.
- W2012259101 hasRelatedWork W4385330994 @default.
- W2012259101 hasVolume "47" @default.
- W2012259101 isParatext "false" @default.
- W2012259101 isRetracted "false" @default.
- W2012259101 magId "2012259101" @default.
- W2012259101 workType "article" @default.