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• W2012261812 endingPage "4499" @default.
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• W2012261812 abstract "FTIR difference spectroscopy, notably in the far-IR domain, is appealing for the analysis of hemoproteins, since it permits us to directly probe the properties of the heme and its ligands but also those of aminoacids remote from the heme. We recently set a thin path-length electrochemical cell with diamond windows allowing the far-IR analysis of proteins in aqueous solutions using FTIR difference spectroscopy (Berthomieu, C,; Marboutin, L.; Dupeyrat, F.; Bouyer, P. Biopolymers 2006 82, 363−367). In this study, we used this cell to identify redox-sensitive low-frequency IR modes of imidazole complexes of Fe-protoporphyrin IX and microperoxidase-8 and analyzed the pH dependence of these modes. The far-IR bands of the heme and the axial imidazole ligands were assigned using 15N2-, and d3-imidazole isotopic substitution, as well as imidazole substitution by 4(5)-methylimidazole. Internal modes of the axial histidine and imidazole ligands were identified in the 670−580 cm−1 region, which are sensitive to the iron coordination (five-coordinated high-spin heme or six-coordinated low-spin heme) and the protonation states of the axial ligands. We showed that deformation modes of the heme pyrroles dominate the 420−370 cm−1 region of the difference spectra. These modes were highly sensitive to the coordination and redox states of the heme iron and the conformation of the tetrapyrrole. While no νas(Fe-axial ligand) IR mode was detected in the difference spectra of the neutral imidazole complexes of Fe-protoporphyrin and microperoxidase, a new mode at 312 and 334 cm−1 was found specific of the imidazolate complexes of Fe3+-protoporphyrin and Fe3+-microperoxidase-8, respectively. On the basis of isotope shifts observed upon ligand deuteration, this band was assigned to a mode mixing the asymmetric stretching of the axial bonds with an internal deformation of the imidazolate rings. These data set the bases for the analysis of the IR low-frequency modes of hemoproteins, and specifically the electronic properties of the heme axial histidine ligands." @default.
• W2012261812 created "2016-06-24" @default.
• W2012261812 creator A5035767716 @default.
• W2012261812 creator A5065223811 @default.
• W2012261812 creator A5076517704 @default.
• W2012261812 date "2009-02-27" @default.
• W2012261812 modified "2023-10-11" @default.
• W2012261812 title "Low-Frequency Heme, Iron-Ligand, and Ligand Modes of Imidazole and Imidazolate Complexes of Iron Protoporphyrin and Microperoxidase in Aqueous Solution. An Analysis by Far-Infrared Difference Spectroscopy" @default.
• W2012261812 cites W137362595 @default.
• W2012261812 cites W1509079182 @default.
• W2012261812 cites W1524704160 @default.
• W2012261812 cites W1524781921 @default.
• W2012261812 cites W1571847781 @default.
• W2012261812 cites W1573337421 @default.
• W2012261812 cites W190537785 @default.
• W2012261812 cites W1964110516 @default.
• W2012261812 cites W1965058508 @default.
• W2012261812 cites W1966361319 @default.
• W2012261812 cites W1967279749 @default.
• W2012261812 cites W1969988861 @default.
• W2012261812 cites W1971528608 @default.
• W2012261812 cites W1983755158 @default.
• W2012261812 cites W1985124629 @default.
• W2012261812 cites W1986580250 @default.
• W2012261812 cites W1986962834 @default.
• W2012261812 cites W1987928455 @default.
• W2012261812 cites W1988766712 @default.
• W2012261812 cites W1989235699 @default.
• W2012261812 cites W1990105684 @default.
• W2012261812 cites W1994113892 @default.
• W2012261812 cites W1995609769 @default.
• W2012261812 cites W1995780649 @default.
• W2012261812 cites W1997265733 @default.
• W2012261812 cites W1999823082 @default.
• W2012261812 cites W2000080047 @default.
• W2012261812 cites W2005435957 @default.
• W2012261812 cites W2005968665 @default.
• W2012261812 cites W2007228310 @default.
• W2012261812 cites W2009042689 @default.
• W2012261812 cites W2009074477 @default.
• W2012261812 cites W2011289735 @default.
• W2012261812 cites W2018339708 @default.
• W2012261812 cites W2018614637 @default.
• W2012261812 cites W2018829588 @default.
• W2012261812 cites W2024147823 @default.
• W2012261812 cites W2024640096 @default.
• W2012261812 cites W2027141115 @default.
• W2012261812 cites W2027827838 @default.
• W2012261812 cites W2036984771 @default.
• W2012261812 cites W2039859606 @default.
• W2012261812 cites W2040944310 @default.
• W2012261812 cites W2042845631 @default.
• W2012261812 cites W2047163585 @default.
• W2012261812 cites W2051533595 @default.
• W2012261812 cites W2053472640 @default.
• W2012261812 cites W2065963208 @default.
• W2012261812 cites W2067644391 @default.
• W2012261812 cites W2070939699 @default.
• W2012261812 cites W2074332333 @default.
• W2012261812 cites W2076495185 @default.
• W2012261812 cites W2080442657 @default.
• W2012261812 cites W2083827361 @default.
• W2012261812 cites W2088903555 @default.
• W2012261812 cites W2090313228 @default.
• W2012261812 cites W2093704016 @default.
• W2012261812 cites W2130271590 @default.
• W2012261812 cites W2134248388 @default.
• W2012261812 cites W2163884737 @default.
• W2012261812 cites W2268780748 @default.
• W2012261812 cites W2949466905 @default.
• W2012261812 cites W2952831323 @default.
• W2012261812 cites W3004604051 @default.
• W2012261812 cites W3004752468 @default.
• W2012261812 cites W3004842070 @default.
• W2012261812 cites W3028068522 @default.
• W2012261812 cites W345458310 @default.
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• W2012261812 doi "https://doi.org/10.1021/jp810774g" @default.
• W2012261812 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19320527" @default.
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