FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012274543> ?p ?o ?g. }

• W2012274543 endingPage "184" @default.
• W2012274543 startingPage "175" @default.
• W2012274543 abstract "Malignant mesothelioma (MM) is resistant to all conventional forms of therapy though there is considerable evidence from clinical trials and animal models of the disease that an immune response can be elicited to the tumour. In order to define those target antigens expressed by MM cells which might provide a focus for an effective immune response we tested patients' sera for the presence of MM autoantibodies by Western blot analysis. Eight of 29 (28%) patients with MM had serum antibodies of the IgG class in high titre and each antiserum recognised different protein antigens. In those individuals where sequential samples were available, the antibody titre increased with the progression of the disease though the number of target antigens remained constant. Sera from the eight patients were studied further: six of the antigen complexes were expressed at least partially in the nucleus; two showed some specificity for the tumour in that they discriminated antigens that were highly expressed in all human MM cell lines, but were not expressed in a human SV40 transformed mesothelial line; four of the antisera recognised a homologue in mouse tissue and each of these had a different pattern of expression. Collectively, these antisera define a subset of nuclear autoantigens that are over-expressed in dividing cells." @default.
• W2012274543 created "2016-06-24" @default.
• W2012274543 creator A5017506323 @default.
• W2012274543 date "1998-06-01" @default.
• W2012274543 modified "2023-10-09" @default.
• W2012274543 title "Sera from patients with malignant mesothelioma can contain autoantibodies" @default.
• W2012274543 cites W1139223896 @default.
• W2012274543 cites W1514412248 @default.
• W2012274543 cites W1898564551 @default.
• W2012274543 cites W1971302107 @default.
• W2012274543 cites W1979568379 @default.
• W2012274543 cites W1980153171 @default.
• W2012274543 cites W1991838289 @default.
• W2012274543 cites W1992847016 @default.
• W2012274543 cites W1997623337 @default.
• W2012274543 cites W1998738169 @default.
• W2012274543 cites W2007749743 @default.
• W2012274543 cites W2008980266 @default.
• W2012274543 cites W2009115410 @default.
• W2012274543 cites W2013582624 @default.
• W2012274543 cites W2033048285 @default.
• W2012274543 cites W2040333460 @default.
• W2012274543 cites W2040796340 @default.
• W2012274543 cites W2059483129 @default.
• W2012274543 cites W2062125067 @default.
• W2012274543 cites W2089425858 @default.
• W2012274543 cites W2101060005 @default.
• W2012274543 cites W2101240557 @default.
• W2012274543 cites W2110458134 @default.
• W2012274543 cites W2110742677 @default.
• W2012274543 cites W2112378746 @default.
• W2012274543 cites W2114657480 @default.
• W2012274543 cites W2130185552 @default.
• W2012274543 cites W2141178172 @default.
• W2012274543 cites W2146600597 @default.
• W2012274543 cites W2147202630 @default.
• W2012274543 cites W2249404753 @default.
• W2012274543 cites W2288667417 @default.
• W2012274543 cites W2407920764 @default.
• W2012274543 cites W3021254998 @default.
• W2012274543 doi "https://doi.org/10.1016/s0169-5002(98)00014-2" @default.
• W2012274543 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9733052" @default.
• W2012274543 hasPublicationYear "1998" @default.
• W2012274543 type Work @default.
• W2012274543 sameAs 2012274543 @default.
• W2012274543 citedByCount "24" @default.
• W2012274543 countsByYear W20122745432012 @default.
• W2012274543 countsByYear W20122745432013 @default.
• W2012274543 countsByYear W20122745432015 @default.
• W2012274543 countsByYear W20122745432016 @default.
• W2012274543 countsByYear W20122745432017 @default.
• W2012274543 countsByYear W20122745432018 @default.
• W2012274543 countsByYear W20122745432019 @default.
• W2012274543 crossrefType "journal-article" @default.
• W2012274543 hasAuthorship W2012274543A5017506323 @default.
• W2012274543 hasConcept C104317684 @default.
• W2012274543 hasConcept C142724271 @default.
• W2012274543 hasConcept C147483822 @default.
• W2012274543 hasConcept C159654299 @default.
• W2012274543 hasConcept C163764329 @default.
• W2012274543 hasConcept C203014093 @default.
• W2012274543 hasConcept C2776415932 @default.
• W2012274543 hasConcept C2777407522 @default.
• W2012274543 hasConcept C32611913 @default.
• W2012274543 hasConcept C55493867 @default.
• W2012274543 hasConcept C71924100 @default.
• W2012274543 hasConcept C86803240 @default.
• W2012274543 hasConcept C8891405 @default.
• W2012274543 hasConcept C91523082 @default.
• W2012274543 hasConceptScore W2012274543C104317684 @default.
• W2012274543 hasConceptScore W2012274543C142724271 @default.
• W2012274543 hasConceptScore W2012274543C147483822 @default.
• W2012274543 hasConceptScore W2012274543C159654299 @default.
• W2012274543 hasConceptScore W2012274543C163764329 @default.
• W2012274543 hasConceptScore W2012274543C203014093 @default.
• W2012274543 hasConceptScore W2012274543C2776415932 @default.
• W2012274543 hasConceptScore W2012274543C2777407522 @default.
• W2012274543 hasConceptScore W2012274543C32611913 @default.
• W2012274543 hasConceptScore W2012274543C55493867 @default.
• W2012274543 hasConceptScore W2012274543C71924100 @default.
• W2012274543 hasConceptScore W2012274543C86803240 @default.
• W2012274543 hasConceptScore W2012274543C8891405 @default.
• W2012274543 hasConceptScore W2012274543C91523082 @default.
• W2012274543 hasIssue "3" @default.
• W2012274543 hasLocation W20122745431 @default.
• W2012274543 hasLocation W20122745432 @default.
• W2012274543 hasOpenAccess W2012274543 @default.
• W2012274543 hasPrimaryLocation W20122745431 @default.
• W2012274543 hasRelatedWork W1494372634 @default.
• W2012274543 hasRelatedWork W1536816732 @default.
• W2012274543 hasRelatedWork W1821997135 @default.
• W2012274543 hasRelatedWork W1830270182 @default.
• W2012274543 hasRelatedWork W2079830858 @default.
• W2012274543 hasRelatedWork W2178718402 @default.
• W2012274543 hasRelatedWork W2356060231 @default.
• W2012274543 hasRelatedWork W2368890815 @default.
• W2012274543 hasRelatedWork W2466764880 @default.
• W2012274543 hasRelatedWork W4313366611 @default.

• next