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• W2012295364 abstract "In this study, the interaction of an alkylating agent, sulfur mustard (SM) with rat liver active (S1 and S2) and inactive (P2) chromatin was investigated employing UV/vis spectroscopy and gel electrophoreses. The results show that SM affects the chromatin structure in a dose-dependent manner. The binding of SM to fractions is different. At lower concentrations (<500 μM), SM seems to unfold the structure and at higher concentrations, it induces aggregation and condensation of chromatin possibly via forming cross-links between the chromatin components. The extent of condensation in S2 is higher when compared to the P2 fraction." @default.
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• W2012295364 date "2010-01-01" @default.
• W2012295364 modified "2023-10-16" @default.
• W2012295364 title "Interaction of sulfur mustard with rat liver salt fractionated chromatin" @default.
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• W2012295364 doi "https://doi.org/10.1016/j.ijbiomac.2009.10.006" @default.
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