FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012296166> ?p ?o ?g. }

• W2012296166 endingPage "5590" @default.
• W2012296166 startingPage "5590" @default.
• W2012296166 abstract "purpose. To define the pattern of Rb expression relative to cell cycle position and cell type in the developing human retina. methods. Cryosections of fetal week 11-18 retinas were immunostained for Rb and cell cycle– or cell type–specific markers. results. Rb was prominent in retinal progenitor cells (RPCs) expressing the cyclin D1, cyclin A, and cytoplasmic cyclin B markers of G1, S, and early to mid G2 phases, but not in RPCs expressing the phosphohistone H3 marker of late G2 and M. Rb was not detected in the earliest postmitotic ganglion, amacrine, horizontal, and bipolar cell precursors migrating away from the ventricular layer, but was detected as such cells underwent further differentiation. Among photoreceptors, Rb was not detected in the earliest RXRγ(+) cone precursors or in the earliest Nrl(+) rod precursors, but subsequently rose to high levels in cones and to low levels in rods. Rb was prominent at the time when Müller glia exit the cell cycle and was generally expressed in a pattern complementary to p27Kip1. conclusions. Rb exhibits cell cycle–specific expression in RPCs, with loss in late G2-M and restoration in G1. Rb is re-expressed after postmitotic ganglion, amacrine, horizontal, and bipolar cell precursors migrate away from the ventricular layer; after the appearance of early cone and rod markers; but coinciding with Müller glia cell cycle withdrawal. The results suggest that Rb does not mediate the initial proliferative arrest of retinal neurons, but may indirectly induce arrest in RPCs or maintain an arrest in postmitotic precursors." @default.
• W2012296166 created "2016-06-24" @default.
• W2012296166 creator A5008258799 @default.
• W2012296166 creator A5035308703 @default.
• W2012296166 creator A5047847872 @default.
• W2012296166 creator A5055676893 @default.
• W2012296166 creator A5072332924 @default.
• W2012296166 date "2006-12-01" @default.
• W2012296166 modified "2023-10-17" @default.
• W2012296166 title "Cell Cycle–Specific and Cell Type–Specific Expression of Rb in the Developing Human Retina" @default.
• W2012296166 cites W1533487943 @default.
• W2012296166 cites W1600375733 @default.
• W2012296166 cites W1944062041 @default.
• W2012296166 cites W1965921684 @default.
• W2012296166 cites W1967075996 @default.
• W2012296166 cites W1972593924 @default.
• W2012296166 cites W1975477048 @default.
• W2012296166 cites W1986148855 @default.
• W2012296166 cites W1991323262 @default.
• W2012296166 cites W1997399224 @default.
• W2012296166 cites W1997875633 @default.
• W2012296166 cites W1997956353 @default.
• W2012296166 cites W1998492363 @default.
• W2012296166 cites W1999970417 @default.
• W2012296166 cites W2021189161 @default.
• W2012296166 cites W2026996045 @default.
• W2012296166 cites W2028868015 @default.
• W2012296166 cites W2029882556 @default.
• W2012296166 cites W2033585891 @default.
• W2012296166 cites W2038170578 @default.
• W2012296166 cites W2038973062 @default.
• W2012296166 cites W2041598409 @default.
• W2012296166 cites W2041662769 @default.
• W2012296166 cites W2042209221 @default.
• W2012296166 cites W2048109276 @default.
• W2012296166 cites W2053550195 @default.
• W2012296166 cites W2065906581 @default.
• W2012296166 cites W2068265875 @default.
• W2012296166 cites W2071214003 @default.
• W2012296166 cites W2078954708 @default.
• W2012296166 cites W2088940942 @default.
• W2012296166 cites W2091404660 @default.
• W2012296166 cites W2093160906 @default.
• W2012296166 cites W2093538714 @default.
• W2012296166 cites W2098877912 @default.
• W2012296166 cites W2099545629 @default.
• W2012296166 cites W2106902623 @default.
• W2012296166 cites W2107766440 @default.
• W2012296166 cites W2111434225 @default.
• W2012296166 cites W2115612876 @default.
• W2012296166 cites W2119509728 @default.
• W2012296166 cites W2127946085 @default.
• W2012296166 cites W2129588996 @default.
• W2012296166 cites W2130624857 @default.
• W2012296166 cites W2133075731 @default.
• W2012296166 cites W2141596803 @default.
• W2012296166 cites W2144490778 @default.
• W2012296166 cites W2148209107 @default.
• W2012296166 cites W2153857274 @default.
• W2012296166 cites W2163570884 @default.
• W2012296166 cites W2166388925 @default.
• W2012296166 cites W2169376100 @default.
• W2012296166 cites W2182438567 @default.
• W2012296166 cites W2411181147 @default.
• W2012296166 cites W2094525939 @default.
• W2012296166 doi "https://doi.org/10.1167/iovs.06-0063" @default.
• W2012296166 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17122153" @default.
• W2012296166 hasPublicationYear "2006" @default.
• W2012296166 type Work @default.
• W2012296166 sameAs 2012296166 @default.
• W2012296166 citedByCount "45" @default.
• W2012296166 countsByYear W20122961662012 @default.
• W2012296166 countsByYear W20122961662013 @default.
• W2012296166 countsByYear W20122961662014 @default.
• W2012296166 countsByYear W20122961662015 @default.
• W2012296166 countsByYear W20122961662016 @default.
• W2012296166 countsByYear W20122961662017 @default.
• W2012296166 countsByYear W20122961662018 @default.
• W2012296166 countsByYear W20122961662019 @default.
• W2012296166 countsByYear W20122961662020 @default.
• W2012296166 countsByYear W20122961662021 @default.
• W2012296166 countsByYear W20122961662022 @default.
• W2012296166 crossrefType "journal-article" @default.
• W2012296166 hasAuthorship W2012296166A5008258799 @default.
• W2012296166 hasAuthorship W2012296166A5035308703 @default.
• W2012296166 hasAuthorship W2012296166A5047847872 @default.
• W2012296166 hasAuthorship W2012296166A5055676893 @default.
• W2012296166 hasAuthorship W2012296166A5072332924 @default.
• W2012296166 hasBestOaLocation W20122961661 @default.
• W2012296166 hasConcept C105702510 @default.
• W2012296166 hasConcept C120089663 @default.
• W2012296166 hasConcept C1491633281 @default.
• W2012296166 hasConcept C169760540 @default.
• W2012296166 hasConcept C189014844 @default.
• W2012296166 hasConcept C199835354 @default.
• W2012296166 hasConcept C2777093970 @default.
• W2012296166 hasConcept C2777506830 @default.
• W2012296166 hasConcept C2780188069 @default.

• next