Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012304944> ?p ?o ?g. }
- W2012304944 endingPage "485" @default.
- W2012304944 startingPage "480" @default.
- W2012304944 abstract "The effects of moderate hyperthyroidism on lipid metabolism were investigated in six healthy subjects before and after thyroxine treatment (300 micrograms/d). T4-treatment increased basal metabolic rate (+8%) and glucose oxidation (+87%), without affecting lipid oxidation, plasma free fatty acids, glycerol, and beta-hydroxybutyrate. During euthyroidism, a hypoinsulinaemic-euglycaemic 150-minute clamp protocol increased energy expenditure (+3%), lipid oxidation (+42%), plasma free fatty acids (+254%), glycerol (+232%), and beta-hydroxybutyrate (+343%), but decreased glucose oxidation (-20%). Similar effects were observed after T4-treatment, but hyperthyroidism induced disproportionate increases in energy expenditure (+7%), plasma glycerol (+310%), and ketone body levels (+436%). We conclude that moderate hyperthyroidism enhances hypoinsulinemia-induced increases in lipolysis, free fatty acid recycling, and ketogenesis without affecting lipid oxidation. Thus basal insulin may camouflage some of thyroid hormone action on lipid metabolism." @default.
- W2012304944 created "2016-06-24" @default.
- W2012304944 creator A5019004457 @default.
- W2012304944 creator A5043894570 @default.
- W2012304944 creator A5050205832 @default.
- W2012304944 creator A5079735260 @default.
- W2012304944 date "1990-05-01" @default.
- W2012304944 modified "2023-10-15" @default.
- W2012304944 title "Thyroid hormone action on lipid metabolism in humans: A role for endogenous insulin" @default.
- W2012304944 cites W1970545032 @default.
- W2012304944 cites W1982427302 @default.
- W2012304944 cites W1983618856 @default.
- W2012304944 cites W1997576546 @default.
- W2012304944 cites W2002253807 @default.
- W2012304944 cites W2005706995 @default.
- W2012304944 cites W2007418665 @default.
- W2012304944 cites W2009953313 @default.
- W2012304944 cites W2012898950 @default.
- W2012304944 cites W2022992765 @default.
- W2012304944 cites W2031313995 @default.
- W2012304944 cites W2044611878 @default.
- W2012304944 cites W2044991896 @default.
- W2012304944 cites W2046105635 @default.
- W2012304944 cites W2049558566 @default.
- W2012304944 cites W2055768459 @default.
- W2012304944 cites W2067406703 @default.
- W2012304944 cites W2068731305 @default.
- W2012304944 cites W2073371928 @default.
- W2012304944 cites W2080750216 @default.
- W2012304944 cites W2083792240 @default.
- W2012304944 cites W2089118497 @default.
- W2012304944 cites W2094375502 @default.
- W2012304944 cites W2098578065 @default.
- W2012304944 cites W2105139877 @default.
- W2012304944 cites W2110320179 @default.
- W2012304944 cites W2121997106 @default.
- W2012304944 cites W2135790024 @default.
- W2012304944 cites W2141439046 @default.
- W2012304944 cites W2150768905 @default.
- W2012304944 cites W2335241585 @default.
- W2012304944 cites W2339461160 @default.
- W2012304944 cites W73695452 @default.
- W2012304944 doi "https://doi.org/10.1016/0026-0495(90)90006-x" @default.
- W2012304944 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1970848" @default.
- W2012304944 hasPublicationYear "1990" @default.
- W2012304944 type Work @default.
- W2012304944 sameAs 2012304944 @default.
- W2012304944 citedByCount "15" @default.
- W2012304944 countsByYear W20123049442018 @default.
- W2012304944 countsByYear W20123049442020 @default.
- W2012304944 countsByYear W20123049442021 @default.
- W2012304944 crossrefType "journal-article" @default.
- W2012304944 hasAuthorship W2012304944A5019004457 @default.
- W2012304944 hasAuthorship W2012304944A5043894570 @default.
- W2012304944 hasAuthorship W2012304944A5050205832 @default.
- W2012304944 hasAuthorship W2012304944A5079735260 @default.
- W2012304944 hasConcept C126322002 @default.
- W2012304944 hasConcept C134018914 @default.
- W2012304944 hasConcept C140985366 @default.
- W2012304944 hasConcept C141359234 @default.
- W2012304944 hasConcept C171089720 @default.
- W2012304944 hasConcept C185592680 @default.
- W2012304944 hasConcept C2778004101 @default.
- W2012304944 hasConcept C2779306644 @default.
- W2012304944 hasConcept C2994476132 @default.
- W2012304944 hasConcept C31532488 @default.
- W2012304944 hasConcept C4733338 @default.
- W2012304944 hasConcept C543025807 @default.
- W2012304944 hasConcept C55493867 @default.
- W2012304944 hasConcept C62231903 @default.
- W2012304944 hasConcept C71315377 @default.
- W2012304944 hasConcept C71924100 @default.
- W2012304944 hasConcept C82714985 @default.
- W2012304944 hasConcept C84693403 @default.
- W2012304944 hasConcept C86803240 @default.
- W2012304944 hasConceptScore W2012304944C126322002 @default.
- W2012304944 hasConceptScore W2012304944C134018914 @default.
- W2012304944 hasConceptScore W2012304944C140985366 @default.
- W2012304944 hasConceptScore W2012304944C141359234 @default.
- W2012304944 hasConceptScore W2012304944C171089720 @default.
- W2012304944 hasConceptScore W2012304944C185592680 @default.
- W2012304944 hasConceptScore W2012304944C2778004101 @default.
- W2012304944 hasConceptScore W2012304944C2779306644 @default.
- W2012304944 hasConceptScore W2012304944C2994476132 @default.
- W2012304944 hasConceptScore W2012304944C31532488 @default.
- W2012304944 hasConceptScore W2012304944C4733338 @default.
- W2012304944 hasConceptScore W2012304944C543025807 @default.
- W2012304944 hasConceptScore W2012304944C55493867 @default.
- W2012304944 hasConceptScore W2012304944C62231903 @default.
- W2012304944 hasConceptScore W2012304944C71315377 @default.
- W2012304944 hasConceptScore W2012304944C71924100 @default.
- W2012304944 hasConceptScore W2012304944C82714985 @default.
- W2012304944 hasConceptScore W2012304944C84693403 @default.
- W2012304944 hasConceptScore W2012304944C86803240 @default.
- W2012304944 hasIssue "5" @default.
- W2012304944 hasLocation W20123049441 @default.
- W2012304944 hasLocation W20123049442 @default.
- W2012304944 hasOpenAccess W2012304944 @default.