Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012305544> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2012305544 endingPage "594" @default.
- W2012305544 startingPage "592" @default.
- W2012305544 abstract "Several bone matrix protein constituents, including the major component collagen type I and the hydroxyapatite binding protein, osteocalcin, have been implicated in the regulation of bone turnover. Cortical bone osteocalcin, collagen and mineral content were studied in autosomal dominant osteopetrosis type I (ADO), a disorder characterized by diffuse symmetrical osteosclerosis. Iliac crest bone biopsies were obtained from eight patients (mean age 43.0 years, range 17-63 years) and compared with 16 age- and sex-matched normal controls (mean age 44.1 years, range 20-61 years). The osteocalcin level in cortical bone was increased (p < 0.03) in ADO (51.4 +/- 3.9 mg/kg bone) compared with controls (38.0 +/- 3.6 mg/kg bone). Total collagen, protein and calcium expressed per kilogram bone dry weight were without significant difference between patients and controls. The pathogenesis of ADO is most likely not related to cortical bone osteocalcin content, a protein implicated in osteoclast ontogeny and activation. These observations are in contrast to recent observations of reduced bone osteocalcin levels in osteopetrotic mutations in the rat and underscore the interspecies heterogeneity of this disorder." @default.
- W2012305544 created "2016-06-24" @default.
- W2012305544 creator A5019266819 @default.
- W2012305544 creator A5031362021 @default.
- W2012305544 creator A5045197704 @default.
- W2012305544 creator A5081119848 @default.
- W2012305544 creator A5090837888 @default.
- W2012305544 date "1994-06-01" @default.
- W2012305544 modified "2023-10-07" @default.
- W2012305544 title "Cortical bone osteocalcin content and matrix composition in autosomal dominant osteopetrosis type I" @default.
- W2012305544 doi "https://doi.org/10.1530/eje.0.1300592" @default.
- W2012305544 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8205260" @default.
- W2012305544 hasPublicationYear "1994" @default.
- W2012305544 type Work @default.
- W2012305544 sameAs 2012305544 @default.
- W2012305544 citedByCount "15" @default.
- W2012305544 countsByYear W20123055442012 @default.
- W2012305544 countsByYear W20123055442014 @default.
- W2012305544 countsByYear W20123055442015 @default.
- W2012305544 crossrefType "journal-article" @default.
- W2012305544 hasAuthorship W2012305544A5019266819 @default.
- W2012305544 hasAuthorship W2012305544A5031362021 @default.
- W2012305544 hasAuthorship W2012305544A5045197704 @default.
- W2012305544 hasAuthorship W2012305544A5081119848 @default.
- W2012305544 hasAuthorship W2012305544A5090837888 @default.
- W2012305544 hasConcept C105702510 @default.
- W2012305544 hasConcept C126322002 @default.
- W2012305544 hasConcept C131075544 @default.
- W2012305544 hasConcept C134018914 @default.
- W2012305544 hasConcept C142724271 @default.
- W2012305544 hasConcept C160160445 @default.
- W2012305544 hasConcept C170033053 @default.
- W2012305544 hasConcept C170493617 @default.
- W2012305544 hasConcept C181199279 @default.
- W2012305544 hasConcept C185592680 @default.
- W2012305544 hasConcept C2776033226 @default.
- W2012305544 hasConcept C2777479973 @default.
- W2012305544 hasConcept C2779079599 @default.
- W2012305544 hasConcept C2780644872 @default.
- W2012305544 hasConcept C2781078528 @default.
- W2012305544 hasConcept C2781451080 @default.
- W2012305544 hasConcept C55493867 @default.
- W2012305544 hasConcept C71924100 @default.
- W2012305544 hasConceptScore W2012305544C105702510 @default.
- W2012305544 hasConceptScore W2012305544C126322002 @default.
- W2012305544 hasConceptScore W2012305544C131075544 @default.
- W2012305544 hasConceptScore W2012305544C134018914 @default.
- W2012305544 hasConceptScore W2012305544C142724271 @default.
- W2012305544 hasConceptScore W2012305544C160160445 @default.
- W2012305544 hasConceptScore W2012305544C170033053 @default.
- W2012305544 hasConceptScore W2012305544C170493617 @default.
- W2012305544 hasConceptScore W2012305544C181199279 @default.
- W2012305544 hasConceptScore W2012305544C185592680 @default.
- W2012305544 hasConceptScore W2012305544C2776033226 @default.
- W2012305544 hasConceptScore W2012305544C2777479973 @default.
- W2012305544 hasConceptScore W2012305544C2779079599 @default.
- W2012305544 hasConceptScore W2012305544C2780644872 @default.
- W2012305544 hasConceptScore W2012305544C2781078528 @default.
- W2012305544 hasConceptScore W2012305544C2781451080 @default.
- W2012305544 hasConceptScore W2012305544C55493867 @default.
- W2012305544 hasConceptScore W2012305544C71924100 @default.
- W2012305544 hasIssue "6" @default.
- W2012305544 hasLocation W20123055441 @default.
- W2012305544 hasLocation W20123055442 @default.
- W2012305544 hasOpenAccess W2012305544 @default.
- W2012305544 hasPrimaryLocation W20123055441 @default.
- W2012305544 hasRelatedWork W1978519211 @default.
- W2012305544 hasRelatedWork W1995872259 @default.
- W2012305544 hasRelatedWork W2062409761 @default.
- W2012305544 hasRelatedWork W2106015885 @default.
- W2012305544 hasRelatedWork W2394867363 @default.
- W2012305544 hasRelatedWork W2405052837 @default.
- W2012305544 hasRelatedWork W2415798131 @default.
- W2012305544 hasRelatedWork W2422447379 @default.
- W2012305544 hasRelatedWork W2471881877 @default.
- W2012305544 hasRelatedWork W2799402627 @default.
- W2012305544 hasVolume "130" @default.
- W2012305544 isParatext "false" @default.
- W2012305544 isRetracted "false" @default.
- W2012305544 magId "2012305544" @default.
- W2012305544 workType "article" @default.