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- W2012309088 abstract "We studied the effect of heavy metal cations: Fe 2+, Cu2+, Zn2+, Cd2+, Hg2+, Pb2+ on the activity of cathepsin D in human aorta homogenate and blood serum. The concentration of cations was 1 mmol/l. Hemoglobin was the cathepsin D substrate. The activity of cathepsin D was determined at pH 3.5. Only Hg2+ cations inhibit the activity of cathepsin D. Cations Hg2+ damage lysosomes and release cathepsin D from these organelles." @default.
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- W2012309088 date "2012-10-08" @default.
- W2012309088 modified "2023-09-25" @default.
- W2012309088 title "Effect of heavy metal cations on the activity of cathepsin D (in vitro study)" @default.
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- W2012309088 doi "https://doi.org/10.5603/19753" @default.
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