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- W2012316752 abstract "Abstract Experimental results are presented which suggest that the G-F transformation of actin is a cooperative phenomenon. One of these results is concerned with the relation between the initial rate of transformation and the G-actin concentration. The initial rate increases in proportion to the third to fourth power of G-actin concentration. The dephosphorylation of ATP on G-actin requires the cooperation of two or more G-actin molecules; and the formation of the nucleus of F-actin by three or four G-actins promotes the further transformation of G-actin. The addition of F-actin accelerates the transformation of G-actin and this is further evidence that the G-F transformation of actin is a cooperative phenomenon. Under various salt conditions the transformation rate increases remarkably when increasing amounts of F-actin are added. Moreover, immediately after the addition of F-actin, explosive dephosphorylation of ATP and transformation of G-actin occur." @default.
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- W2012316752 date "1962-01-01" @default.
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- W2012316752 title "The cooperative nature of G-F transformation of actin" @default.
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- W2012316752 doi "https://doi.org/10.1016/0006-3002(62)91073-9" @default.
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