FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012324886> ?p ?o ?g. }

• W2012324886 endingPage "213" @default.
• W2012324886 startingPage "206" @default.
• W2012324886 abstract "Preduodenal lipolysis is considered to promote efficient lipid digestion in the neonatal period. The lipase(s) responsible may be of pregastric or gastric origin depending upon the species. We have previously reported on purification and molecular characterization of a pregastric lipase from calf. Antibodies to this bovine enzyme crossreact with a protein of similar size in human gastric contents and also inhibit its lipolytic activity. Since the bovine and human enzymes also have similar kinetic properties, the view is favoured that the bovine enzyme can be used as a model for physiological studies relevant to human neonates. In contrast to the lipases operating in the small intestine pregastric lipase has the unique property of initiating the hydrolysis of human milk fat globule triacylglycerol. In order to do this no cofactor is required. Pregastric lipase was stable at low pH and had an acid-pH optimum. Furthermore, it was extremely resistant to pepsin. In contrast, pancreatic proteinases i.e. trypsin and chymotrypsin, inactivated the enzyme. The rate of inactivation was increased in the presence of bile salts which by themselves could inhibit enzyme activity. Thus, pregastric lipase is ideally suited for activity in the stomach but will not, under healthy conditions, contribute to lipid digestion in the duodenum." @default.
• W2012324886 created "2016-06-24" @default.
• W2012324886 creator A5019216446 @default.
• W2012324886 creator A5043655805 @default.
• W2012324886 creator A5054562379 @default.
• W2012324886 date "1987-11-01" @default.
• W2012324886 modified "2023-10-17" @default.
• W2012324886 title "Bovine pregastric lipase: a model for the human enzyme with respect to properties relevant to its site of action" @default.
• W2012324886 cites W1485466859 @default.
• W2012324886 cites W1486503774 @default.
• W2012324886 cites W1579899042 @default.
• W2012324886 cites W1677547851 @default.
• W2012324886 cites W1715568103 @default.
• W2012324886 cites W1781803044 @default.
• W2012324886 cites W1890547526 @default.
• W2012324886 cites W1970683900 @default.
• W2012324886 cites W1976471991 @default.
• W2012324886 cites W1981975854 @default.
• W2012324886 cites W1990091395 @default.
• W2012324886 cites W199016929 @default.
• W2012324886 cites W1999924895 @default.
• W2012324886 cites W2000297056 @default.
• W2012324886 cites W2004243895 @default.
• W2012324886 cites W2006334209 @default.
• W2012324886 cites W2018865990 @default.
• W2012324886 cites W2034370425 @default.
• W2012324886 cites W2045773580 @default.
• W2012324886 cites W2047732473 @default.
• W2012324886 cites W2072054150 @default.
• W2012324886 cites W2073879684 @default.
• W2012324886 cites W2078926624 @default.
• W2012324886 cites W2083170568 @default.
• W2012324886 cites W2091731990 @default.
• W2012324886 cites W2093792489 @default.
• W2012324886 cites W2094413622 @default.
• W2012324886 cites W2097044276 @default.
• W2012324886 cites W2100837269 @default.
• W2012324886 cites W2130153207 @default.
• W2012324886 cites W2220000844 @default.
• W2012324886 cites W2323684245 @default.
• W2012324886 cites W92219093 @default.
• W2012324886 cites W94077231 @default.
• W2012324886 doi "https://doi.org/10.1016/0005-2760(87)90156-1" @default.
• W2012324886 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3676343" @default.
• W2012324886 hasPublicationYear "1987" @default.
• W2012324886 type Work @default.
• W2012324886 sameAs 2012324886 @default.
• W2012324886 citedByCount "19" @default.
• W2012324886 countsByYear W20123248862012 @default.
• W2012324886 countsByYear W20123248862016 @default.
• W2012324886 countsByYear W20123248862017 @default.
• W2012324886 crossrefType "journal-article" @default.
• W2012324886 hasAuthorship W2012324886A5019216446 @default.
• W2012324886 hasAuthorship W2012324886A5043655805 @default.
• W2012324886 hasAuthorship W2012324886A5054562379 @default.
• W2012324886 hasConcept C127947577 @default.
• W2012324886 hasConcept C140985366 @default.
• W2012324886 hasConcept C16311235 @default.
• W2012324886 hasConcept C171089720 @default.
• W2012324886 hasConcept C181199279 @default.
• W2012324886 hasConcept C185592680 @default.
• W2012324886 hasConcept C2778401398 @default.
• W2012324886 hasConcept C2779697368 @default.
• W2012324886 hasConcept C2780340462 @default.
• W2012324886 hasConcept C2780786110 @default.
• W2012324886 hasConcept C2781357212 @default.
• W2012324886 hasConcept C28212737 @default.
• W2012324886 hasConcept C43617362 @default.
• W2012324886 hasConcept C55493867 @default.
• W2012324886 hasConcept C94412978 @default.
• W2012324886 hasConceptScore W2012324886C127947577 @default.
• W2012324886 hasConceptScore W2012324886C140985366 @default.
• W2012324886 hasConceptScore W2012324886C16311235 @default.
• W2012324886 hasConceptScore W2012324886C171089720 @default.
• W2012324886 hasConceptScore W2012324886C181199279 @default.
• W2012324886 hasConceptScore W2012324886C185592680 @default.
• W2012324886 hasConceptScore W2012324886C2778401398 @default.
• W2012324886 hasConceptScore W2012324886C2779697368 @default.
• W2012324886 hasConceptScore W2012324886C2780340462 @default.
• W2012324886 hasConceptScore W2012324886C2780786110 @default.
• W2012324886 hasConceptScore W2012324886C2781357212 @default.
• W2012324886 hasConceptScore W2012324886C28212737 @default.
• W2012324886 hasConceptScore W2012324886C43617362 @default.
• W2012324886 hasConceptScore W2012324886C55493867 @default.
• W2012324886 hasConceptScore W2012324886C94412978 @default.
• W2012324886 hasIssue "2" @default.
• W2012324886 hasLocation W20123248861 @default.
• W2012324886 hasLocation W20123248862 @default.
• W2012324886 hasOpenAccess W2012324886 @default.
• W2012324886 hasPrimaryLocation W20123248861 @default.
• W2012324886 hasRelatedWork W2012324886 @default.
• W2012324886 hasRelatedWork W2028570530 @default.
• W2012324886 hasRelatedWork W2058180897 @default.
• W2012324886 hasRelatedWork W2069852998 @default.
• W2012324886 hasRelatedWork W2077861403 @default.
• W2012324886 hasRelatedWork W2142024608 @default.
• W2012324886 hasRelatedWork W2167833923 @default.
• W2012324886 hasRelatedWork W3006872796 @default.

• next