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- W2012325465 abstract "Abstract Sodium deficient, unlike normal calves, will push a panel vigorously for Li + or Na + salts. In 5 min (VI 20 sec) operant tests calves (n=5) pressed for 10 ml rewards of 0.3 M NaHCO 3 , NaCl, Na 2 SO 4 , LiCl and Li 2 SO 4 . When the tests were extended to 20 min, LiCl responses were reduced significantly in a few days and the aversion transferred to NaCl, Na 2 SO 4 and Li 2 SO 4 but the NaHCO 3 response remained at a high level. No signs of lithium toxicity were detectable. Lithium naive calves (n=2) given a single LiCl IV infusion which raised the plasma lithium to 12.5±1.3 mEq/l did not exhibit any reduction in Li or Na appetite. In 3 of the 5 calves mentioned above which had ingested lithium salts an IV injection of LiCl reduced their appetite for all Na and Li salts tested except for NaHCO 3 . This suggests that either there is some retention of lithium within the body to produce avoidance behaviour when plasma lithium is raised or a taste memory of the aversive effects produced by raised plasma Li + exists. The Li + aversion, which varies between calves, appears to be connected directly with intake and the effect fades in weeks or months. The distinct selection made for NaHCO 3 illustrates the importance of this salt for the survival of Na + depleted calves." @default.
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- W2012325465 date "1981-07-01" @default.
- W2012325465 modified "2023-09-23" @default.
- W2012325465 title "Effect of lithium intake on sodium and lithium appetite in sodium deficient cattle☆" @default.
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- W2012325465 doi "https://doi.org/10.1016/0031-9384(81)90312-7" @default.
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