Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012327355> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2012327355 abstract "Biophosphonates are analogues of pyrophosphate. The mechanism of action of bisphosphates is the inhibition of osteoclast activation (antiresorptive mechanism). The oral bioavailability of biophosphonates is only about 1-2%, and because of gastrointestinal side effects (mainly esophageal irritation), oral agents are less useful in oncology. Biophosphonates are used for the treatment of Paget s disease of bone, the prevention of osteoporosis, and in another clinical scenarios as the prevention of bone disease after organ transplantation. In clinical oncology biophosphonates are used for the treatment of hypercalcemia of malignancy, prevention and treatment of bone events related to bone metastases, and in the prevention of osteoporosis related to breast cancer. According to American Society of Clinical Oncology (ACO) guidelines, biophosphonates should be used in hypercalcemia of malignancy and bone events related to metastases of breast cancer and multiple myeloma." @default.
- W2012327355 created "2016-06-24" @default.
- W2012327355 creator A5042231848 @default.
- W2012327355 creator A5077954020 @default.
- W2012327355 date "2005-11-01" @default.
- W2012327355 modified "2023-10-16" @default.
- W2012327355 title "Bifosfonatos en oncología" @default.
- W2012327355 cites W1951349736 @default.
- W2012327355 cites W1972544033 @default.
- W2012327355 cites W1982145456 @default.
- W2012327355 cites W1983856948 @default.
- W2012327355 cites W2014164632 @default.
- W2012327355 cites W2069957538 @default.
- W2012327355 cites W2070636400 @default.
- W2012327355 cites W2083149897 @default.
- W2012327355 cites W2102969047 @default.
- W2012327355 cites W2107118598 @default.
- W2012327355 cites W2115335453 @default.
- W2012327355 cites W2138220544 @default.
- W2012327355 cites W2141521877 @default.
- W2012327355 cites W2159100092 @default.
- W2012327355 cites W2783103906 @default.
- W2012327355 cites W2506838919 @default.
- W2012327355 doi "https://doi.org/10.4321/s0212-71992005001100011" @default.
- W2012327355 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16454591" @default.
- W2012327355 hasPublicationYear "2005" @default.
- W2012327355 type Work @default.
- W2012327355 sameAs 2012327355 @default.
- W2012327355 citedByCount "4" @default.
- W2012327355 countsByYear W20123273552013 @default.
- W2012327355 countsByYear W20123273552014 @default.
- W2012327355 countsByYear W20123273552015 @default.
- W2012327355 crossrefType "journal-article" @default.
- W2012327355 hasAuthorship W2012327355A5042231848 @default.
- W2012327355 hasAuthorship W2012327355A5077954020 @default.
- W2012327355 hasBestOaLocation W20123273551 @default.
- W2012327355 hasConcept C121608353 @default.
- W2012327355 hasConcept C126322002 @default.
- W2012327355 hasConcept C143998085 @default.
- W2012327355 hasConcept C170493617 @default.
- W2012327355 hasConcept C2776033226 @default.
- W2012327355 hasConcept C2776169692 @default.
- W2012327355 hasConcept C2776364478 @default.
- W2012327355 hasConcept C2776541429 @default.
- W2012327355 hasConcept C2776598537 @default.
- W2012327355 hasConcept C2779399171 @default.
- W2012327355 hasConcept C530470458 @default.
- W2012327355 hasConcept C71924100 @default.
- W2012327355 hasConceptScore W2012327355C121608353 @default.
- W2012327355 hasConceptScore W2012327355C126322002 @default.
- W2012327355 hasConceptScore W2012327355C143998085 @default.
- W2012327355 hasConceptScore W2012327355C170493617 @default.
- W2012327355 hasConceptScore W2012327355C2776033226 @default.
- W2012327355 hasConceptScore W2012327355C2776169692 @default.
- W2012327355 hasConceptScore W2012327355C2776364478 @default.
- W2012327355 hasConceptScore W2012327355C2776541429 @default.
- W2012327355 hasConceptScore W2012327355C2776598537 @default.
- W2012327355 hasConceptScore W2012327355C2779399171 @default.
- W2012327355 hasConceptScore W2012327355C530470458 @default.
- W2012327355 hasConceptScore W2012327355C71924100 @default.
- W2012327355 hasIssue "11" @default.
- W2012327355 hasLocation W20123273551 @default.
- W2012327355 hasLocation W20123273552 @default.
- W2012327355 hasOpenAccess W2012327355 @default.
- W2012327355 hasPrimaryLocation W20123273551 @default.
- W2012327355 hasRelatedWork W1534854101 @default.
- W2012327355 hasRelatedWork W1575059564 @default.
- W2012327355 hasRelatedWork W2012327355 @default.
- W2012327355 hasRelatedWork W2013596522 @default.
- W2012327355 hasRelatedWork W2084492568 @default.
- W2012327355 hasRelatedWork W2240066772 @default.
- W2012327355 hasRelatedWork W2400014005 @default.
- W2012327355 hasRelatedWork W274396811 @default.
- W2012327355 hasRelatedWork W3121104609 @default.
- W2012327355 hasRelatedWork W2183938888 @default.
- W2012327355 hasVolume "22" @default.
- W2012327355 isParatext "false" @default.
- W2012327355 isRetracted "false" @default.
- W2012327355 magId "2012327355" @default.
- W2012327355 workType "article" @default.