Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012340118> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2012340118 endingPage "447" @default.
- W2012340118 startingPage "444" @default.
- W2012340118 abstract "Colonization by enteric gram-negative bacteria with subsequent translocation is believed to be a major mechanism for infection in the critically ill patient. Selective bowel decontamination (SBD) has been used to control gram-negative infections by eliminating these potentially pathogenic bacteria while preserving anaerobic and other less pathogenic organisms. Infection with gram-positive organisms and anaerobes in two multivisceral transplant patients during SBD led us to investigate the effect of SBD on gut colonization and translocation. Methods: Twenty-four rats received enteral polymixin E, tobramycin, amphotericin B, and parenteral cefotaxime for 7 days (PTA + CEF); 23 received parenteral cefotaxime alone (CEF), 19 received the enteral antibiotics alone (PTA), 21 controls received no antibiotics. Cecal homogenates, mesenteric lymph node (MLN), liver, and spleen were cultured. Results: Only 8% of the PTA + CEF group had gram-negative bacteria in cecal culture vs 52% CEF, 84% PTA, and 100% in controls. Log Enterococcal colony counts were higher in the PTA + CEF group (8.0 + 0.9) vs controls (5.4 + 0.4) P < 0.01. Translocation of Enterococcus to the MLN was significantly increased in the PTA + CEF group (67%) vs controls (0%) P < 0.01. SBD effectively eliminates gram-negative organisms from the gut in the rat model. Overgrowth and translocation of Enterococcus suggests that infection with grampositive organisms may be a limitation of SBD." @default.
- W2012340118 created "2016-06-24" @default.
- W2012340118 creator A5008218354 @default.
- W2012340118 creator A5024215519 @default.
- W2012340118 creator A5074389432 @default.
- W2012340118 date "1990-05-01" @default.
- W2012340118 modified "2023-09-27" @default.
- W2012340118 title "Selective bowel decontamination results in gram-positive translocation" @default.
- W2012340118 cites W1692894082 @default.
- W2012340118 cites W1905885715 @default.
- W2012340118 cites W1936658752 @default.
- W2012340118 cites W1952384394 @default.
- W2012340118 cites W1975830627 @default.
- W2012340118 cites W1984731911 @default.
- W2012340118 cites W2003634472 @default.
- W2012340118 cites W2009060883 @default.
- W2012340118 cites W2013949755 @default.
- W2012340118 cites W2014806496 @default.
- W2012340118 cites W2050490859 @default.
- W2012340118 cites W2054619588 @default.
- W2012340118 cites W2063703864 @default.
- W2012340118 cites W2067834213 @default.
- W2012340118 cites W2077405044 @default.
- W2012340118 cites W2113792102 @default.
- W2012340118 cites W2149333078 @default.
- W2012340118 cites W2153623513 @default.
- W2012340118 cites W2410645950 @default.
- W2012340118 doi "https://doi.org/10.1016/0022-4804(90)90010-y" @default.
- W2012340118 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2352419" @default.
- W2012340118 hasPublicationYear "1990" @default.
- W2012340118 type Work @default.
- W2012340118 sameAs 2012340118 @default.
- W2012340118 citedByCount "36" @default.
- W2012340118 countsByYear W20123401182015 @default.
- W2012340118 countsByYear W20123401182016 @default.
- W2012340118 countsByYear W20123401182019 @default.
- W2012340118 crossrefType "journal-article" @default.
- W2012340118 hasAuthorship W2012340118A5008218354 @default.
- W2012340118 hasAuthorship W2012340118A5024215519 @default.
- W2012340118 hasAuthorship W2012340118A5074389432 @default.
- W2012340118 hasConcept C126322002 @default.
- W2012340118 hasConcept C2775832221 @default.
- W2012340118 hasConcept C2777677444 @default.
- W2012340118 hasConcept C2778719061 @default.
- W2012340118 hasConcept C2778974779 @default.
- W2012340118 hasConcept C2779237934 @default.
- W2012340118 hasConcept C2780585763 @default.
- W2012340118 hasConcept C2780931953 @default.
- W2012340118 hasConcept C501593827 @default.
- W2012340118 hasConcept C71924100 @default.
- W2012340118 hasConcept C86803240 @default.
- W2012340118 hasConcept C89423630 @default.
- W2012340118 hasConcept C90924648 @default.
- W2012340118 hasConceptScore W2012340118C126322002 @default.
- W2012340118 hasConceptScore W2012340118C2775832221 @default.
- W2012340118 hasConceptScore W2012340118C2777677444 @default.
- W2012340118 hasConceptScore W2012340118C2778719061 @default.
- W2012340118 hasConceptScore W2012340118C2778974779 @default.
- W2012340118 hasConceptScore W2012340118C2779237934 @default.
- W2012340118 hasConceptScore W2012340118C2780585763 @default.
- W2012340118 hasConceptScore W2012340118C2780931953 @default.
- W2012340118 hasConceptScore W2012340118C501593827 @default.
- W2012340118 hasConceptScore W2012340118C71924100 @default.
- W2012340118 hasConceptScore W2012340118C86803240 @default.
- W2012340118 hasConceptScore W2012340118C89423630 @default.
- W2012340118 hasConceptScore W2012340118C90924648 @default.
- W2012340118 hasIssue "5" @default.
- W2012340118 hasLocation W20123401181 @default.
- W2012340118 hasLocation W20123401182 @default.
- W2012340118 hasOpenAccess W2012340118 @default.
- W2012340118 hasPrimaryLocation W20123401181 @default.
- W2012340118 hasRelatedWork W1928255277 @default.
- W2012340118 hasRelatedWork W2012340118 @default.
- W2012340118 hasRelatedWork W2059780464 @default.
- W2012340118 hasRelatedWork W2070623546 @default.
- W2012340118 hasRelatedWork W2097690524 @default.
- W2012340118 hasRelatedWork W2127701647 @default.
- W2012340118 hasRelatedWork W2144756362 @default.
- W2012340118 hasRelatedWork W2407342460 @default.
- W2012340118 hasRelatedWork W3004506113 @default.
- W2012340118 hasRelatedWork W4309344478 @default.
- W2012340118 hasVolume "48" @default.
- W2012340118 isParatext "false" @default.
- W2012340118 isRetracted "false" @default.
- W2012340118 magId "2012340118" @default.
- W2012340118 workType "article" @default.