FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012356109> ?p ?o ?g. }

• W2012356109 endingPage "262" @default.
• W2012356109 startingPage "256" @default.
• W2012356109 abstract "To compare cerebral and hemodynamic consequences of different volumes of cold acetated Ringer's solution or cold hypertonic saline dextran administered in order to achieve mild hypothermia after cardiac arrest (CA) in a pig model of experimental cardiopulmonary resuscitation (CPR).Using an experimental pig model of 12 min CA (followed by 8 min CPR or no resuscitation) we compared four groups of piglets: a control group, a normothermic group and two groups with different solutions administered for induction of hypothermia. The control group of 5 piglets underwent 12 min CA without subsequent CPR, after which the brain of the animals was removed immediately. After restoration of spontaneous circulation (ROSC) the resuscitated piglets were randomized into a normothermic group (NT group=10), and two hypothermic groups that received cold infusions of either 30 mL/kg acetated Ringer's solution (Much fluid group, M, n=10) or 3mL/kg hypertonic saline dextran solution (Less fluid group, L, n=10), respectively, administered during 30 min. Additional external cooling with ice packs was used in hypothermic groups. Sixty or 180min after ROSC the experiment was terminated. Immediately after arrest the brain was removed for histological analyses.The median time to reach the target core temperature of 34 °C after ROSC was 51.5±7.8 min in L group and 48.8±8.6 min in M group. Less cerebral tissue content of water (p<0.001), sodium (p<0.0001), potassium (p<0.0001) and less central venous pressure (CVP) at 5 and 15 min after ROSC were demonstrated in L group. Increased brain damage was demonstrated over time in NT group (p<0.001). Less neurologic damage and BBB disruptions (albumin leakage) was observed at 180min in M group in comparison with both NT and L groups (p<0.001).No statistical differences were observed between the hypothermic groups in the time to achieve mild hypothermia. Although inclusion of cold hypertonic crystalloid-colloidal solutions in the early resuscitation after ROSC may be more effective than cold crystalloids in reducing brain edema, this study demonstrates that mild hypothermia induced with small volumes of cold hypertonic crystalloid-colloids is less as effective as crystalloid's induced hypothermia in mitigating brain injury after cardiac arrest." @default.
• W2012356109 created "2016-06-24" @default.
• W2012356109 creator A5042830074 @default.
• W2012356109 creator A5070996328 @default.
• W2012356109 creator A5075343449 @default.
• W2012356109 date "2013-02-01" @default.
• W2012356109 modified "2023-09-27" @default.
• W2012356109 title "Crystalloid vs. hypertonic crystalloid–colloid solutions for induction of mild therapeutic hypothermia after experimental cardiac arrest" @default.
• W2012356109 cites W1503600085 @default.
• W2012356109 cites W1973406593 @default.
• W2012356109 cites W1981105814 @default.
• W2012356109 cites W1993999756 @default.
• W2012356109 cites W1995191071 @default.
• W2012356109 cites W1999311858 @default.
• W2012356109 cites W2007372190 @default.
• W2012356109 cites W2013284267 @default.
• W2012356109 cites W2032710625 @default.
• W2012356109 cites W2048218698 @default.
• W2012356109 cites W2060017971 @default.
• W2012356109 cites W2062642814 @default.
• W2012356109 cites W2074871884 @default.
• W2012356109 cites W2075206379 @default.
• W2012356109 cites W2099784599 @default.
• W2012356109 cites W2100703339 @default.
• W2012356109 cites W2104383304 @default.
• W2012356109 cites W2104869294 @default.
• W2012356109 cites W2108884129 @default.
• W2012356109 cites W2110045115 @default.
• W2012356109 cites W2121714044 @default.
• W2012356109 cites W2148432472 @default.
• W2012356109 cites W2159465073 @default.
• W2012356109 cites W2170972390 @default.
• W2012356109 cites W2171218071 @default.
• W2012356109 cites W2917971741 @default.
• W2012356109 cites W4251758568 @default.
• W2012356109 doi "https://doi.org/10.1016/j.resuscitation.2012.06.024" @default.
• W2012356109 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22771870" @default.
• W2012356109 hasPublicationYear "2013" @default.
• W2012356109 type Work @default.
• W2012356109 sameAs 2012356109 @default.
• W2012356109 citedByCount "6" @default.
• W2012356109 countsByYear W20123561092015 @default.
• W2012356109 countsByYear W20123561092017 @default.
• W2012356109 countsByYear W20123561092021 @default.
• W2012356109 countsByYear W20123561092022 @default.
• W2012356109 crossrefType "journal-article" @default.
• W2012356109 hasAuthorship W2012356109A5042830074 @default.
• W2012356109 hasAuthorship W2012356109A5070996328 @default.
• W2012356109 hasAuthorship W2012356109A5075343449 @default.
• W2012356109 hasConcept C117277713 @default.
• W2012356109 hasConcept C126322002 @default.
• W2012356109 hasConcept C178853913 @default.
• W2012356109 hasConcept C185592680 @default.
• W2012356109 hasConcept C2777055891 @default.
• W2012356109 hasConcept C2777339698 @default.
• W2012356109 hasConcept C2777390192 @default.
• W2012356109 hasConcept C2777397205 @default.
• W2012356109 hasConcept C2778165595 @default.
• W2012356109 hasConcept C2778619729 @default.
• W2012356109 hasConcept C2778872873 @default.
• W2012356109 hasConcept C2910384157 @default.
• W2012356109 hasConcept C3017567848 @default.
• W2012356109 hasConcept C42219234 @default.
• W2012356109 hasConcept C55493867 @default.
• W2012356109 hasConcept C71924100 @default.
• W2012356109 hasConceptScore W2012356109C117277713 @default.
• W2012356109 hasConceptScore W2012356109C126322002 @default.
• W2012356109 hasConceptScore W2012356109C178853913 @default.
• W2012356109 hasConceptScore W2012356109C185592680 @default.
• W2012356109 hasConceptScore W2012356109C2777055891 @default.
• W2012356109 hasConceptScore W2012356109C2777339698 @default.
• W2012356109 hasConceptScore W2012356109C2777390192 @default.
• W2012356109 hasConceptScore W2012356109C2777397205 @default.
• W2012356109 hasConceptScore W2012356109C2778165595 @default.
• W2012356109 hasConceptScore W2012356109C2778619729 @default.
• W2012356109 hasConceptScore W2012356109C2778872873 @default.
• W2012356109 hasConceptScore W2012356109C2910384157 @default.
• W2012356109 hasConceptScore W2012356109C3017567848 @default.
• W2012356109 hasConceptScore W2012356109C42219234 @default.
• W2012356109 hasConceptScore W2012356109C55493867 @default.
• W2012356109 hasConceptScore W2012356109C71924100 @default.
• W2012356109 hasIssue "2" @default.
• W2012356109 hasLocation W20123561091 @default.
• W2012356109 hasLocation W20123561092 @default.
• W2012356109 hasOpenAccess W2012356109 @default.
• W2012356109 hasPrimaryLocation W20123561091 @default.
• W2012356109 hasRelatedWork W13981640 @default.
• W2012356109 hasRelatedWork W1990784591 @default.
• W2012356109 hasRelatedWork W2012356109 @default.
• W2012356109 hasRelatedWork W2023430430 @default.
• W2012356109 hasRelatedWork W2037669548 @default.
• W2012356109 hasRelatedWork W2049847729 @default.
• W2012356109 hasRelatedWork W2083945676 @default.
• W2012356109 hasRelatedWork W2164586945 @default.
• W2012356109 hasRelatedWork W3013586860 @default.
• W2012356109 hasRelatedWork W2245202200 @default.
• W2012356109 hasVolume "84" @default.
• W2012356109 isParatext "false" @default.

• next