Matches in SemOpenAlex for { <https://semopenalex.org/work/W201235712> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W201235712 endingPage "700" @default.
- W201235712 startingPage "695" @default.
- W201235712 abstract "The authors analyzed the BerH2 reactivity patterns of the tumor cells in 23 Hodgkin's lymphomas (HD), in 13 CD30+ anaplastic large cell (Ki1) lymphomas (ALCL), in two HD with transition to secondary CD30+ ALCL, and in six additional lymphomas intermediate between HD and ALCL.Paraffin blocks of formalin-fixed biopsies were immunostained. Immunostaining was modified by pronase digestion and by microwave assistance.Hodgkin-Reed-Sternberg (HRS) cells of all 23 Hodgkin's lymphomas were reactive for BerH2, but the reactivity patterns differed: after pronase digestion, HRS cells of 17/23 Hodgkin's lymphomas showed exclusively or at least predominantly cytoplasmic BerH2 reactivity, whereas only four Hodgkin's lymphomas presented with prominent membrane-bound positivity. Microwave processing in 16/23 Hodgkin's lymphomas induced membrane-bound BerH2 positivity in the HRS cells; a minority of five cases retained the distinct cytoplasmic pattern. In contrast, 10/13 ALCLs were characterized by membranous reactions, independent of whether pronase or microwave pretreatment had been applied. The CD30+ ALCLs secondary to HD also showed a tendency towards membranous positivity more than did the antecedent Hodgkin's lymphomas. In the HD/ALCL borderline group, 3/6 cases revealed cytoplasmic BerH2 patterns after pronase digestion and thus were more closely related to HD, whereas 2/6 cases reacted with membranous positivity as did the genuine ALCLs of our series.We conclude from these findings that the above modifications in CD30 immunostaining can be helpful in the characterization of lymphomas that constitute a continuous histomorphological as well as phenotypical spectrum between HD and ALCL." @default.
- W201235712 created "2016-06-24" @default.
- W201235712 creator A5018594954 @default.
- W201235712 creator A5047405133 @default.
- W201235712 creator A5081352725 @default.
- W201235712 date "1998-11-01" @default.
- W201235712 modified "2023-09-23" @default.
- W201235712 title "CD30 Differential Staining is Useful in Classifying Lymphomas Intermediate between Hodgkin's Disease and Anaplastic Large Cell (Ki1) Lymphoma" @default.
- W201235712 cites W1028569293 @default.
- W201235712 cites W144665287 @default.
- W201235712 cites W1965608727 @default.
- W201235712 cites W1977729651 @default.
- W201235712 cites W1989696211 @default.
- W201235712 cites W2018829699 @default.
- W201235712 cites W2051485548 @default.
- W201235712 cites W2057824616 @default.
- W201235712 cites W2058457260 @default.
- W201235712 cites W2091332309 @default.
- W201235712 cites W2120535659 @default.
- W201235712 cites W2164828476 @default.
- W201235712 cites W2314274799 @default.
- W201235712 cites W2332732913 @default.
- W201235712 cites W2335205686 @default.
- W201235712 doi "https://doi.org/10.1177/030089169808400617" @default.
- W201235712 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10080680" @default.
- W201235712 hasPublicationYear "1998" @default.
- W201235712 type Work @default.
- W201235712 sameAs 201235712 @default.
- W201235712 citedByCount "3" @default.
- W201235712 crossrefType "journal-article" @default.
- W201235712 hasAuthorship W201235712A5018594954 @default.
- W201235712 hasAuthorship W201235712A5047405133 @default.
- W201235712 hasAuthorship W201235712A5081352725 @default.
- W201235712 hasConcept C142724271 @default.
- W201235712 hasConcept C181199279 @default.
- W201235712 hasConcept C185592680 @default.
- W201235712 hasConcept C204232928 @default.
- W201235712 hasConcept C2776708817 @default.
- W201235712 hasConcept C2777872185 @default.
- W201235712 hasConcept C2779338263 @default.
- W201235712 hasConcept C2780340462 @default.
- W201235712 hasConcept C2780430958 @default.
- W201235712 hasConcept C2992779791 @default.
- W201235712 hasConcept C4224716 @default.
- W201235712 hasConcept C55493867 @default.
- W201235712 hasConcept C70905583 @default.
- W201235712 hasConcept C71924100 @default.
- W201235712 hasConcept C74864618 @default.
- W201235712 hasConcept C86803240 @default.
- W201235712 hasConceptScore W201235712C142724271 @default.
- W201235712 hasConceptScore W201235712C181199279 @default.
- W201235712 hasConceptScore W201235712C185592680 @default.
- W201235712 hasConceptScore W201235712C204232928 @default.
- W201235712 hasConceptScore W201235712C2776708817 @default.
- W201235712 hasConceptScore W201235712C2777872185 @default.
- W201235712 hasConceptScore W201235712C2779338263 @default.
- W201235712 hasConceptScore W201235712C2780340462 @default.
- W201235712 hasConceptScore W201235712C2780430958 @default.
- W201235712 hasConceptScore W201235712C2992779791 @default.
- W201235712 hasConceptScore W201235712C4224716 @default.
- W201235712 hasConceptScore W201235712C55493867 @default.
- W201235712 hasConceptScore W201235712C70905583 @default.
- W201235712 hasConceptScore W201235712C71924100 @default.
- W201235712 hasConceptScore W201235712C74864618 @default.
- W201235712 hasConceptScore W201235712C86803240 @default.
- W201235712 hasIssue "6" @default.
- W201235712 hasLocation W2012357121 @default.
- W201235712 hasLocation W2012357122 @default.
- W201235712 hasOpenAccess W201235712 @default.
- W201235712 hasPrimaryLocation W2012357121 @default.
- W201235712 hasRelatedWork W1932831713 @default.
- W201235712 hasRelatedWork W1979802226 @default.
- W201235712 hasRelatedWork W201235712 @default.
- W201235712 hasRelatedWork W2077594293 @default.
- W201235712 hasRelatedWork W2126451971 @default.
- W201235712 hasRelatedWork W2242689536 @default.
- W201235712 hasRelatedWork W2317011243 @default.
- W201235712 hasRelatedWork W2408237879 @default.
- W201235712 hasRelatedWork W3031905168 @default.
- W201235712 hasRelatedWork W5804915 @default.
- W201235712 hasVolume "84" @default.
- W201235712 isParatext "false" @default.
- W201235712 isRetracted "false" @default.
- W201235712 magId "201235712" @default.
- W201235712 workType "article" @default.