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• W2012391532 abstract "Alignments of homologous genes typically reveal a great diversity of intron locations, far more than could fit comfortably in a single gene. Thus, a minority of these intron positions could be inherited from a single ancestral gene, but the larger share must be attributed to subsequent events of intron gain or intron sliding (movement from one position to another within a gene). Intron sliding has been argued from cases of discordant introns and from putative spatial clustering of intron positions. A list of 32 cases of discordant introns is presented here. Most of these cases are found to be artefactual. The spatial and phylogenetic distributions of intron positions from five published compilations of gene data, comprising 205 intron positions, have been examined systematically for evidence of intron sliding. The results suggest that sliding, if it occurs at all, has contributed little to the diversity of intron positions." @default.
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• W2012391532 date "1997-09-30" @default.
• W2012391532 modified "2023-10-13" @default.
• W2012391532 title "Intron “sliding” and the diversity of intron positions" @default.
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• W2012391532 doi "https://doi.org/10.1073/pnas.94.20.10739" @default.
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