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- W2012434319 abstract "IDENTIFICATIONs of bacterial origin elaborated in strangulation intestinal obstruction has been a major project of this laboratory. 1 Clostridial exotoxins have been implicated as lethal agents in experimental studies with rabbits, 2 guinea pigs (unpublished data), rats, 3 and pups. 3 Other investigators have implicated bacterial endotoxins 4 and viable bacteria 5 as the toxic agents. Terminal peritoneal fluid and loop contents have been the specimens usually examined for toxicity. The bacterial population of peritoneal fluid aspirated at intervals from the same dog has been shown to remain low until 12 to 18 hr after surgery, when the phase of logarithmic growth was achieved by the endogenous intestinal bacteria. 6 In the work reported here groups of dogs were sacrificed at specified times after strangulation to obtain the contents of isolated closed loops. Methods The intestines of 28 dogs were divided at a site three fourths of the distance" @default.
- W2012434319 created "2016-06-24" @default.
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- W2012434319 date "1963-02-16" @default.
- W2012434319 modified "2023-09-26" @default.
- W2012434319 title "Serial Changes of Intestinal Contents in Strangulation Obstruction" @default.
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- W2012434319 doi "https://doi.org/10.1001/jama.1963.63700070012009c" @default.
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